HIT-result

Type	Detail
Target ID	T47G3X
Protein Name	Glucocorticoid receptor
Uniprot ID	P04150
Protein Name Alias	GR; Nuclear receptor subfamily 3 group C member 1
Gene ID	2908
Gene Symbol	NR3C1
Gene Alias	GRL
TTD	T40016: Successful target
Pfam	PF02155 ; PF00105 ; PF00104
GO	0006355:regulation of transcription, DNA-templated 0006325:chromatin organization 0032991:protein-containing complex 0005819:spindle 1990837:sequence-specific double-stranded DNA binding 1990239:steroid hormone binding 0004883:glucocorticoid receptor activity 0071383:cellular response to steroid hormone stimulus 0005829:cytosol 0004879:nuclear receptor activity 0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding 0006915:apoptotic process 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0071549:cellular response to dexamethasone stimulus 1902895:positive regulation of pri-miRNA transcription by RNA polymerase II 0005654:nucleoplasm 0005815:microtubule organizing center 0005737:cytoplasm 0001046:core promoter sequence-specific DNA binding 0030518:intracellular steroid hormone receptor signaling pathway 0008270:zinc ion binding 0003723:RNA binding 0007049:cell cycle 0000785:chromatin 0003700:DNA-binding transcription factor activity 0045944:positive regulation of transcription by RNA polymerase II 0016607:nuclear speck 0071385:cellular response to glucocorticoid stimulus 0005496:steroid binding 0005634:nucleus 0019901:protein kinase binding 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005759:mitochondrial matrix 0051879:Hsp90 protein binding 0007059:chromosome segregation 0006367:transcription initiation from RNA polymerase II promoter 0045892:negative regulation of transcription, DNA-templated 0071560:cellular response to transforming growth factor beta stimulus 0051301:cell division 0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific 0007165:signal transduction 0000122:negative regulation of transcription by RNA polymerase II 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0006357:regulation of transcription by RNA polymerase II
PDB	5EMQ ; 5CC1 ; 5UC3 ; 5EMC ; 3K22 ; 3H52 ; 6CFN ; 5NFT ; 5E6A ; 3E7C ; 5E69 ; 5VA0 ; 1M2Z ; 6DXK ; 3CLD ; 4HN5 ; 4LSJ ; 6EL9 ; 5VA7 ; 6EL6 ; 4MDD ; 5E6C ; 4UDC ; 5E6B ; 3K23 ; 5G5W ; 5G3J ; 4CSJ ; 6EL7 ; 5EMP ; 5CBZ ; 6BQU ; 1NHZ ; 5CBY ; 4P6W ; 1P93 ; 5E6D ; 5NFP ; 3BQD ; 4UDD ; 4P6X ; 4HN6 ; 5CBX
Drugbank	DB00223 ; DB01013 ; DB14512 ; DB08906 ; DB00959 ; DB00769 ; DB00764 ; DB00741 ; DB02210 ; DB00253 ; DB14544 ; DB00324 ; DB05423 ; DB00351 ; DB00396 ; DB14541 ; DB01222 ; DB00838 ; DB00635 ; DB00240 ; DB00547 ; DB14542 ; DB00860 ; DB01410 ; DB14543 ; DB14540 ; DB12637 ; DB00443 ; DB00588 ; DB00288 ; DB14583 ; DB09095 ; DB13867 ; DB13003 ; DB14631 ; DB01260 ; DB00846 ; DB01047 ; DB00394 ; DB11921 ; DB06781 ; DB04630 ; DB14669 ; DB14596 ; DB13158 ; DB09091 ; DB14649 ; DB01395 ; DB00896 ; DB11619 ; DB01234 ; DB08867 ; DB00663 ; DB00180 ; DB14538 ; DB00367 ; DB15566 ; DB01380 ; DB00620 ; DB00687 ; DB00834 ; DB14539 ; DB00591 ; DB01185 ; DB00421 ; DB01130 ; DB01384 ; DB00596 ; DB00717
KEGG	hsa:2908

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Name: Escitalopram

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Name: Estradiol

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Name: Hydrocortisone

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Name: Nicotine

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Name: Spermidine

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Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H1033	Fang Ji	防己	Fourstamen stephania	Stephania tetrandra
H0615	Wu Zhi Mao Tao	五指毛桃	five-finger fig root	Ficus simplicissima
H0236	Mao She Xiang Jin Gao	毛麝香浸膏	Abelmusk	Moschus moschiferus
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H1181	Hei Zhi Ma	黑芝麻	Oriental sesame	Sesamum indicum
H0356	Ren Gong She Xiang	人工麝香	Abelmusk	Moschus moschiferus
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0560	Cao Bei Mu	草贝母	Indian iphigenia	Iphigenia indica
H0026	Jiang	姜	Soybean paste	Glycine max
H0637	Cha Ye	茶叶	Common tea	Camellia sinensis
H0659	Chai Hu Jin Gao	柴胡浸膏	Chinese thorowax	Bupleurum chinense
H1212	Hu Ye Gan Jin Gao	槲叶干浸膏	NA	Quercus dentata
H0092	Ju Hua	菊花	Florists chrysanthemum flower	Chrysanthemum morifolium
H0784	Chi Shao	赤芍	Red peony root	Paeonia obovata
H0965	Deng Zhan Xi Xin	灯盏细辛	Shortscape fleabane	Erigeron breviscapus
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H0631	Xi Yang Shen	西洋参	American ginseng	Panax quinquefolium
H0956	Dang Gui Gan Jin Gao	当归干浸膏	NA	Angelica sinensis
H1207	Hu Ma	胡麻	white seed of oriental sesame	Sesamum indicum
H0310	Pian Qin	片芩	Scutellaria amoena	Scutellaria baicalensis
H1225	Huai Mi	槐米	NA	Sophora japonica
H1029	Fang Er Cha	方儿茶	khair in hindi	Senegalia catechu
H0429	Shao Yao	芍药	Red peony root	Paeonia obovata
H0520	Tai Pan Fen	胎盘粉	Fetus powder	Human placenta
H1133	Gui Jian Yu	鬼箭羽	Winged euonymus	Euonymus alatus
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H0380	San Qi Gan Jin Gao	三七干浸膏	Sanchi	Panax notoginseng
H0341	Qing Feng Teng	青风藤	Orientvine	Sinomenium acutum
H1222	Huai Hua	槐花	flower bud of japanese pagodatree	Sophora japonica
H1227	Huai Zhi	槐枝	NA	Sophora japonica
H1161	Hang Ju	杭菊	Chrysanthemum flower	Chrysanthemum morifolium
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0970	Di Gu Pi	地骨皮	root - bark of chinese wolfberry	Cortex lycii radicis
H0437	She Xiang	麝香	Abelmusk	Moschus moschiferus
H1253	Huang Qin Jin Gao Fen	黄芩浸膏粉	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0951	Dan Shen Jin Gao	丹参浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0522	Tai Zi Shen	太子参	Heterophylly falsestarwort root	Radix pseudostellariae
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H0378	San Qi	三七	Sanchi	Panax notoginseng
H1176	Hei Hu Jiao	黑胡椒	Black pepper	Piper nigrum
H1254	Huang Qin Tan	黄芩炭	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0384	San Qi Ye	三七叶	Folium panax notoginseng	Panax notoginseng
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H1224	Huai Jiao	槐角	pod of japanese pagodatree	Sophora japonica
H0077	Jiu	酒	Ethanol	Vinum
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis
H0661	Xiao Hei Dou	小黑豆	Black turtle bean	Phaseolus vulgaris
H0482	Shui Ban Xia	水半夏	NA	Typhonium flagelliforme
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0665	Chai Hu Shao	柴胡梢	Chinese thorowax	Bupleurum chinense
H0949	Dan Shen	丹参	The root of red-rooted salvia	Salvia miltiorrhiza
H1077	Bai Hu Jiao	白胡椒	white pepper	Piper nigrum
H0194	Ma Bing Lang	马槟榔	Masaikai caper	Capparis masaikai
H0164	Ban Zhi Lian	半枝莲	Barbed skullcap	Scutellaria barbata
H1007	Dou You	豆油	Soybean oil	Glycine max
H0530	Tao Ren Shuang	桃仁霜	Peach kernel	Prunus persica
H0385	San Qi Ye Jing	三七叶茎	Sanchi	Panax notoginseng
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1204	Hu Jiao	胡椒	Black pepper	Piper nigrum
H1240	Huang Jing Zi	黄荆子	NA	Vitex negundo
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0714	Yan Tai Chai Hu	烟台柴胡	Chinese thorowax	Bupleurum chinense
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H1252	Huang Qin Jin Gao	黄芩浸膏	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0382	San Qi Hua	三七花	Sanchi	Panax notoginseng
H0383	San Qi Jing Ye	三七茎叶	Sanchi	Panax notoginseng
H0950	Dan Shen Gan Jin Gao	丹参干浸膏	The root of red-rooted salvia	Salvia miltiorrhiza
H0531	Tao Zhi	桃枝	Peach juvenile branch	Prunus persica
H0381	San Qi Gao Fen	三七膏粉	Sanchi	Panax notoginseng
H0132	Li Lu	藜芦	Black falsehellebore	Veratrum nigrum
H0087	Ju Gu Ye	枸骨叶	FOLIUM iLICIS cORNUTAE	Ilex cornuta
H0235	Mao She Xiang	毛麝香	Abelmusk	Moschus moschiferus
H0938	Da Suan	大蒜	Garlic	Allium sativum
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H0529	Tao Ren	桃仁	Peach kernel	Prunus persica
H1004	Bai Cha	白茶	White tea	Camellia sinensis
H0521	Tai Pan Zu Zhi Fen	胎盘组织粉	NA	Human placenta
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H1014	Du Yi Wei	独一味	Common lamiophlomis	Lamiophlomis rotata
H0650	Chai Hu	柴胡	Chinese thorowax	Bupleurum chinense
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0155	Ban Xia	半夏	Ternate pinellia	Pinellia ternata
H1208	Hu Ma Ren	胡麻仁	white seed of oriental sesame	Sesamum indicum
H0527	Tao	桃	Peach	Prunus persica
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0603	Wu Tong Ye Jin Gao	梧桐叶浸膏	Parasol trees	Firmiana simplex
H0416	Shan Shen	山参	NA	Panax ginseng
H0955	Dang Gui	当归	Chinese angelica	Angelica sinensis

Target Description

Related Compounds (Total: 20)

Related Herbs (Total: 98)