Compound Description

ID:   C0129 Common name:   Hydrocortisone
IUPAC:  (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one CAS:  CAS:50-23-7
Chembl ID:   CHEMBL389621 Pubchem ID:   CID:5754
Formula:  C21H30O5 TCM-ID:  TCMC1340
Smiles:  OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C
Alias:

Cortisol;

(11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;

11β,17,21-Trihydroxypregn-4-ene-3,20-dione;

11β,17,21-Trihydroxyprogesterone;

11β,17α,21-Trihydroxypregn-4-ene-3,20-dione;

11β-Hydroxycortisone;

17-Hydroxycorticosterone;

17α-Hydroxycorticosterone;

4-Pregnene-11β,17α,21-triol-3,20-dione;

Acticort;

Aeroseb HC;

Ala-Cort;

Anflam;

Anti-inflammatory hormone;

CCN 90306A;

CaldeCort Spray;

Cetacort;

Cobadex;

Cort-Dome;

Cortanal;

Cortef;

Cortenema;

Corticreme;

Cortifan;

Cortiment;

Cortispray;

Cortonema;

Cortril;

Dermacort;

Dermocortal;

Dermolate;

Dihydrocostisone;

Dioderm;

Domolene-HC;

DuoCort;

Efcorbin;

Efcortelan;

Eldecort;

Epiderm H;

Esiderm H;

Evacort;

Ficortril;

Genacort;

Heb-Cort;

Hidro-Colisona;

Hycort;

Hycortol;

Hycortole;

Hydracort;

Hydrasson;

Hydro-Adreson;

Hydrocort;

Hydrocortal;

Hydrocorticosterone;

Hydrocortin;

Hydrocortisone;

Hydrocortisyl;

Hydrocortone;

Hydroskin;

Hytone;

Hytone lotion;

Incortin-H;

Infacort;

Kendall's compound F;

Lacticare HC;

Medicort;

Mildison;

NSC 10483;

Nutracort;

Optef;

Otosone-F;

Penecort;

Permicort;

Polcort H;

Reichstein's substance M;

Sanatison;

Scalpicin;

Scheroson F;

Signef;

Synacort;

Tarcortin;

Texacort;

Texacort lotion 25;

Timocort;

Topicort;

Traumaide;

U 1851;

Zenoxone
Structure:

Related Targets  (Total: 9)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T10Z2F Bcl-2-like protein 12BCL2L12 Q9HB09
A 1 Reference(s)
T48QK5 Potassium voltage-gated channel subfamily A member 3KCNA3 P22001
A 1 Reference(s)
T10OYK Corticosteroid-binding globulinSERPINA6 P08185
B 3 Reference(s)
T82JWE Cellular tumor antigen p53TP53 P04637
B 1 Reference(s)
T34IGC DEP domain-containing mTOR-interacting proteinDEPTOR Q8TB45
B 1 Reference(s)
T18YXD AlbuminALB P02768
B 1 Reference(s)
T33OPP Interleukin-6IL6 P05231
C 1 Reference(s)
T12PPL Thyroid hormone receptor betaTHRB P10828
C 1 Reference(s)
T47G3X Glucocorticoid receptorNR3C1 P04150
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0482 Shui Ban Xia水半夏 NATyphonium flagelliforme
H1014 Du Yi Wei独一味 Common lamiophlomisLamiophlomis rotata
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens