HIT-result

Type	Detail
Target ID	T12PPL
Protein Name	Thyroid hormone receptor beta
Uniprot ID	P10828
Protein Name Alias	Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta
Gene ID	7068
Gene Symbol	THRB
Gene Alias	ERBA2; NR1A2; THR1
TTD	T98933: Successful target
Pfam	PF00105 ; PF00104
GO	0003677:DNA binding 0097474:retinal cone cell apoptotic process 0005634:nucleus 0006351:transcription, DNA-templated 0007621:negative regulation of female receptivity 0070324:thyroid hormone binding 0009755:hormone-mediated signaling pathway 0030154:cell differentiation 0031490:chromatin DNA binding 0060509:type I pneumocyte differentiation 0019899:enzyme binding 0007605:sensory perception of sound 0008050:female courtship behavior 0000785:chromatin 0002154:thyroid hormone mediated signaling pathway 0097067:cellular response to thyroid hormone stimulus 0016604:nuclear body 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0000122:negative regulation of transcription by RNA polymerase II 0008270:zinc ion binding 0003700:DNA-binding transcription factor activity 0046549:retinal cone cell development 0006367:transcription initiation from RNA polymerase II promoter 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 1990837:sequence-specific double-stranded DNA binding 0045944:positive regulation of transcription by RNA polymerase II 0004879:nuclear receptor activity 0001225:RNA polymerase II transcription coactivator binding 0008016:regulation of heart contraction
PDB	6KKE ; 1NUO ; 6KNU ; 2J4A ; 3JZC ; 1BSX ; 2PIN ; 1Q4X ; 1Y0X ; 6KNV ; 1NQ2 ; 1NAX ; 1R6G ; 1XZX ; 1NQ0 ; 6KNW ; 6KKB ; 4ZO1 ; 3GWS ; 2NLL ; 3D57 ; 1N46 ; 1NQ1 ; 3IMY
Drugbank	DB03604 ; DB01118 ; DB03788 ; DB02106 ; DB00451 ; DB00279 ; DB03176 ; DB01583 ; DB08085 ; DB03181 ; DB05192 ; DB09100 ; DB07425 ; DB00509 ; DB05035
KEGG	hsa:7068

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Name: Hydrocortisone

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Name: Celecoxib

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1014	Du Yi Wei	独一味	Common lamiophlomis	Lamiophlomis rotata
H0482	Shui Ban Xia	水半夏	NA	Typhonium flagelliforme
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum