HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T00T99	S-adenosylhomocysteine hydrolase-like protein 1	AHCYL1	O43865	1 Reference(s)
T21CMG	Hepcidin	HAMP	P81172	2 Reference(s)
T20RA0	Adenosine deaminase	ADA	P00813	1 Reference(s)
T31ZFD	Aldehyde oxidase	AOX1	Q06278	2 Reference(s)
T93SFQ	NAD-dependent protein deacetylase sirtuin-1	SIRT1	Q96EB6	28 Reference(s)
T86MX7	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	CD38	P28907	2 Reference(s)
T41BXR	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	SIRT3	Q9NTG7	3 Reference(s)
T40DE5	Tryptophan 2,3-dioxygenase	TDO2	P48775	1 Reference(s)
T73LPO	Poly [ADP-ribose] polymerase 1	PARP1	P09874	3 Reference(s)
T21PEZ	NAD(+) hydrolase SARM1	SARM1	Q6SZW1	1 Reference(s)
T22NX4	Toll-like receptor 2	TLR2	O60603	2 Reference(s)
T76QBQ	CREB-regulated transcription coactivator 2	CRTC2	Q53ET0	1 Reference(s)
T21DZX	Amine oxidase [flavin-containing] A	MAOA	P21397	3 Reference(s)
T25M2J	Anoctamin-1	ANO1	Q5XXA6	1 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	5 Reference(s)
T22OPB	Nuclear factor erythroid 2-related factor 2	NFE2L2	Q16236	8 Reference(s)
T58J2Y	Peroxisome proliferator-activated receptor gamma	PPARG	P37231	3 Reference(s)
T62FNY	Adenosine receptor A3	ADORA3	P0DMS8	1 Reference(s)
T47DYR	P2Y purinoceptor 1	P2RY1	P47900	1 Reference(s)
T82JWE	Cellular tumor antigen p53	TP53	P04637	2 Reference(s)
T49ORJ	Peroxisome proliferator-activated receptor alpha	PPARA	Q07869	2 Reference(s)
T63BQU	Cytochrome P450 1A1	CYP1A1	P04798	3 Reference(s)
T34DZ7	Interleukin-2	IL2	P60568	1 Reference(s)
T23VMI	Tumor necrosis factor	TNF	P01375	6 Reference(s)
T64BTV	Interleukin-1 beta	IL1B	P01584	3 Reference(s)
T38N69	Lymphokine-activated killer T-cell-originated protein kinase	PBK	Q96KB5	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	2 Reference(s)
T83P5X	Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	O14920	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	6 Reference(s)
T74LFK	Neurogenic locus notch homolog protein 1	NOTCH1	P46531	1 Reference(s)
T60XJI	Transient receptor potential cation channel subfamily M member 8	TRPM8	Q7Z2W7	1 Reference(s)
T09INZ	Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	2 Reference(s)
T12BGL	Cytochrome P450 2A6	CYP2A6	P11509	1 Reference(s)
T46AXP	Cytochrome P450 2A13	CYP2A13	Q16696	1 Reference(s)
T23P74	Caspase-9	CASP9	P55211	4 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	10 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T14BVD	Protein arginine N-methyltransferase 5	PRMT5	O14744	1 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	1 Reference(s)
T83YZD	Acetylcholinesterase	ACHE	P22303	2 Reference(s)
T81I4T	5'-AMP-activated protein kinase catalytic subunit alpha-1	PRKAA1	Q13131	4 Reference(s)
T37G49	Platelet-activating factor acetylhydrolase	PLA2G7	Q13093	1 Reference(s)
T72U9G	Tumor necrosis factor receptor superfamily member 9	TNFRSF9	Q07011	1 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	3 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	3 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	5 Reference(s)
T53YWQ	Pro-neuropeptide Y [Cleaved into: Neuropeptide Y	NPY	P01303	2 Reference(s)
T60A9R	NA	CYP3A	NA	2 Reference(s)
T43QZ3	Sclerostin	SOST	Q9BQB4	1 Reference(s)
T56TXY	Polyunsaturated fatty acid 5-lipoxygenase	ALOX5	P09917	1 Reference(s)
T32JN2	Beta-glucuronidase	GUSB	P08236	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	3 Reference(s)
T87C5Q	Polyunsaturated fatty acid lipoxygenase ALOX12	ALOX12	P18054	7 Reference(s)
T86D6K	Polyunsaturated fatty acid lipoxygenase ALOX15	ALOX15	P16050	7 Reference(s)
T61SU2	Coxsackievirus and adenovirus receptor	CXADR	P78310	1 Reference(s)
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	1 Reference(s)
T48NTH	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	PIK3CD	O00329	1 Reference(s)
T31JWV	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	PIK3CB	P42338	1 Reference(s)
T32SPJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	P48736	1 Reference(s)
T63YAO	Caveolin-1	CAV1	Q03135	1 Reference(s)
T75HMM	Induced myeloid leukemia cell differentiation protein Mcl-1	MCL1	Q07820	1 Reference(s)
T00RU5	Histone H1.0	H1-0	P07305	1 Reference(s)
T37V37	Prostaglandin-H2 D-isomerase	PTGDS	P41222	1 Reference(s)
T09DI4	Lysine-specific histone demethylase 1A	KDM1A	O60341	1 Reference(s)
T78VUO	RAF proto-oncogene serine/threonine-protein kinase	RAF1	P04049	1 Reference(s)
T25NSJ	Mitogen-activated protein kinase 3	MAPK3	P27361	1 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	3 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	3 Reference(s)
T69XVX	Cytochrome P450 1B1	CYP1B1	Q16678	1 Reference(s)
T09H2Z	Nitric oxide synthase, inducible	NOS2	P35228	1 Reference(s)
T05V67	Toll-like receptor 8	TLR8	Q9NR97	1 Reference(s)
T44LWL	Transcription factor p65	RELA	Q04206	3 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	2 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	8 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	5 Reference(s)
T10HL8	Intercellular adhesion molecule 1	ICAM1	P05362	3 Reference(s)
T75PC7	NA	MIR21	NA	1 Reference(s)
T66G0O	NA	MIR30A	NA	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	1 Reference(s)
T67KTV	Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	1 Reference(s)
T63FF5	Interferon regulatory factor 3	IRF3	Q14653	2 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	3 Reference(s)
T76TED	Pro-opiomelanocortin	POMC	P01189	1 Reference(s)
T37JN5	Neutrophil gelatinase-associated lipocalin	LCN2	P80188	1 Reference(s)
T17UP9	C-C motif chemokine 2	CCL2	P13500	1 Reference(s)
T33OPP	Interleukin-6	IL6	P05231	3 Reference(s)
T64V6C	Glutamate decarboxylase 1	GAD1	Q99259	1 Reference(s)
T83RKS	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	MGAT1	P26572	2 Reference(s)
T73PZA	Vesicular inhibitory amino acid transporter	SLC32A1	Q9H598	1 Reference(s)
T68XXK	4-aminobutyrate aminotransferase, mitochondrial	ABAT	P80404	4 Reference(s)
T35WLZ	Sodium- and chloride-dependent GABA transporter 3	SLC6A11	P48066	2 Reference(s)
T20JZ2	Androgen receptor	AR	P10275	2 Reference(s)
T41Z1X	Gamma-aminobutyric acid receptor-associated protein	GABARAP	O95166	1 Reference(s)
T09GFP	Maltase-glucoamylase, intestinal [Includes: Maltase	MGAM	O43451	1 Reference(s)
T77M4W	Adenosine receptor A2a	ADORA2A	P29274	2 Reference(s)
T72J3R	Secretogranin-1	CHGB	P05060	1 Reference(s)
T26KIE	Transcription factor AP-1	JUN	P05412	2 Reference(s)
T02WMA	Ornithine decarboxylase	ODC1	P11926	1 Reference(s)
T41BYM	Fibroblast growth factor 23	FGF23	Q9GZV9	1 Reference(s)
T85CC2	Peptidyl-prolyl cis-trans isomerase D	PPID	Q08752	1 Reference(s)
T74QXI	Serine/threonine-protein kinase mTOR	MTOR	P42345	1 Reference(s)
T95IYZ	Adiponectin	ADIPOQ	Q15848	1 Reference(s)
T16O4B	CCAAT/enhancer-binding protein epsilon	CEBPE	Q15744	1 Reference(s)
T10WEJ	Betaine--homocysteine S-methyltransferase 1	BHMT	Q93088	1 Reference(s)
T99HGY	Ubiquitin-protein ligase E3A	UBE3A	Q05086	1 Reference(s)
T69NG6	Interleukin-10	IL10	P22301	1 Reference(s)
T51EKP	Apolipoprotein M	APOM	O95445	1 Reference(s)
T07VV7	Guanylin	GUCA2A	Q02747	1 Reference(s)
T67ZT3	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	PTEN	P60484	2 Reference(s)
T80WPU	Protein ABHD15	ABHD15	Q6UXT9	1 Reference(s)
T56OUM	14-3-3 protein zeta/delta	YWHAZ	P63104	1 Reference(s)
T24YWQ	Insulin-degrading enzyme	IDE	P14735	1 Reference(s)
T34HYH	Interleukin-1 alpha	IL1A	P01583	1 Reference(s)
T39M6J	ATP-binding cassette sub-family C member 2	ABCC2	Q92887	1 Reference(s)
T33KFW	Matrilysin	MMP7	P09237	1 Reference(s)
T70SFS	Superoxide dismutase [Mn], mitochondrial	SOD2	P04179	1 Reference(s)
T42D4V	Histone deacetylase 1	HDAC1	Q13547	1 Reference(s)
T54B00	P2X purinoceptor 7	P2RX7	Q99572	1 Reference(s)
T21UJU	Troponin I, cardiac muscle	TNNI3	P19429	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T60UPF	Parvalbumin alpha	PVALB	P20472	2 Reference(s)
T69RXK	Cytochrome P450 2C9	CYP2C9	P11712	1 Reference(s)
T18CUI	Neuron-specific calcium-binding protein hippocalcin	HPCA	P84074	1 Reference(s)
T92BZ2	Catenin beta-1	CTNNB1	P35222	1 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	1 Reference(s)
T39RV3	Dual specificity mitogen-activated protein kinase kinase 1	MAP2K1	Q02750	1 Reference(s)
T66S13	Dual specificity mitogen-activated protein kinase kinase 2	MAP2K2	P36507	1 Reference(s)
T08SJX	Astrocytic phosphoprotein PEA-15	PEA15	Q15121	1 Reference(s)
T38OQ4	Peroxiredoxin-2	PRDX2	P32119	1 Reference(s)
T38J3Y	Gamma-enolase	ENO2	P09104	1 Reference(s)
T77W6N	Thioredoxin reductase 1, cytoplasmic	TXNRD1	Q16881	1 Reference(s)
T10I26	Interferon beta	IFNB1	P01574	1 Reference(s)
T40EUL	Transient receptor potential cation channel subfamily V member 4	TRPV4	Q9HBA0	1 Reference(s)
T98DNG	Natriuretic peptides A	NPPA	P01160	1 Reference(s)
T78ILO	Stearoyl-CoA desaturase	SCD	O00767	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	1 Reference(s)
T68IZC	Natriuretic peptides B	NPPB	P16860	1 Reference(s)
T02H9U	Nuclear factor of activated T-cells, cytoplasmic 4	NFATC4	Q14934	1 Reference(s)
T82D6U	Ubiquitin-like protein ATG12	ATG12	O94817	1 Reference(s)
T24V8E	Ubiquitin-like modifier-activating enzyme ATG7	ATG7	O95352	1 Reference(s)
T24RSX	Autophagy protein 5	ATG5	Q9H1Y0	1 Reference(s)
T95EK6	Microtubule-associated proteins 1A/1B light chain 3B	MAP1LC3B	Q9GZQ8	1 Reference(s)
T43NBB	Solute carrier family 2, facilitated glucose transporter member 2	SLC2A2	P11168	1 Reference(s)
T51WGR	Pancreas/duodenum homeobox protein 1	PDX1	P52945	1 Reference(s)
T82S6C	Hexokinase-4	GCK	P35557	1 Reference(s)
T18CPB	Choline O-acetyltransferase	CHAT	P28329	1 Reference(s)
T30VNV	Myeloperoxidase	MPO	P05164	1 Reference(s)
T03YAI	Mitogen-activated protein kinase kinase kinase 5	MAP3K5	Q99683	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	2 Reference(s)
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	3 Reference(s)
T18DUA	Tight junction protein ZO-1	TJP1	Q07157	1 Reference(s)
T65JUB	Nucleotide-binding oligomerization domain-containing protein 2	NOD2	Q9HC29	2 Reference(s)
T25SMR	Proto-oncogene Wnt-1	WNT1	P04628	1 Reference(s)
T99ARN	Forkhead box protein P3	FOXP3	Q9BZS1	1 Reference(s)
T29B10	Interleukin-17A	IL17A	Q16552	1 Reference(s)
T47G3X	Glucocorticoid receptor	NR3C1	P04150	1 Reference(s)
T19XSL	Fatty acid-binding protein, liver	FABP1	P07148	1 Reference(s)
T12PV0	NA	MEG3	NA	1 Reference(s)
T93YV8	Tumor necrosis factor receptor superfamily member 11B	TNFRSF11B	O00300	1 Reference(s)
T65S3S	Tyrosine-protein kinase JAK2	JAK2	O60674	1 Reference(s)
T08Q1T	Amiloride-sensitive sodium channel subunit alpha	SCNN1A	P37088	1 Reference(s)
T10MFU	DCC-interacting protein 13-beta	APPL2	Q8NEU8	1 Reference(s)
T61J7T	Mothers against decapentaplegic homolog 2	SMAD2	Q15796	1 Reference(s)
T78O6C	Mothers against decapentaplegic homolog 3	SMAD3	P84022	1 Reference(s)
T86ROZ	Heme oxygenase 1	HMOX1	P09601	1 Reference(s)
T85AXP	Cytochrome P450 3A4	CYP3A4	P08684	1 Reference(s)
T03CZ8	Catechol O-methyltransferase	COMT	P21964	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	1 Reference(s)
T57GP2	ETS domain-containing protein Elk-1	ELK1	P19419	1 Reference(s)
T68OIU	CREB-regulated transcription coactivator 1	CRTC1	Q6UUV9	1 Reference(s)
T17CZC	Tissue factor	F3	P13726	2 Reference(s)
T48TW0	Platelet glycoprotein 4	CD36	P16671	2 Reference(s)
T10S5F	Cyclin-dependent kinase 4	CDK4	P11802	1 Reference(s)
T41TXS	Retinoblastoma-associated protein	RB1	P06400	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T02IOG	Cyclin-dependent kinase inhibitor 1B	CDKN1B	P46527	1 Reference(s)

Herb ID: H0155	Chinese Character: 半夏
English Name: Ternate pinellia	Latin Name: Pinellia ternata
Chinese Pin Yin : Ban Xia	TCM-ID: TCMH130
Therapeutic Function in Chinese : 化痰止咳平喘	Therapeutic Function in English: For desolving phlegm, stopping cougth, and soothing breathing
Herb Function: Remove damp and phlegm, relieve nausea and vomiting, and eliminate stuffiness in the chest and the epigastrium

Herb Description

Related Targets (Total: 181)

Related Compounds (Total: 37)