Target Description
| Type | Detail |
|---|---|
| Target ID | T40DE5 |
| Protein Name | Tryptophan 2,3-dioxygenase |
| Uniprot ID |
P48775 |
| Protein Name Alias | TDO; EC 1.13.11.11; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; TO; TRPO; Tryptophan pyrrolase; Tryptophanase |
| Gene ID |
6999 |
| Gene Symbol | TDO2 |
| Gene Alias | TDO |
| TTD | T44818: Clinical Trial target |
| Pfam | PF03301 |
| GO |
0042802:identical protein binding
0019441:tryptophan catabolic process to kynurenine 0051289:protein homotetramerization 0016597:amino acid binding 0020037:heme binding 0046872:metal ion binding 1904842:response to nitroglycerin 0019442:tryptophan catabolic process to acetyl-CoA 0004833:tryptophan 2,3-dioxygenase activity 0019825:oxygen binding 0005829:cytosol 0006569:tryptophan catabolic process |
| PDB | 5TIA ; 5TI9 ; 4PW8 ; 6PYY ; 6VBN ; 6PYZ ; 6A4I |
| Drugbank | DB00500 ; DB00779 ; DB00150 |
| KEGG | hsa:6999 |
Related Compounds (Total: 3)
Related Herbs (Total: 9)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0809 | Zhi Mu | 知母 | Common anemarrhena | Anemarrhena asphodeloides |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0623 | Xi Hong Hua | 西红花 | Saffron | Stigma croci |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H0364 | Rou Cong Rong | 肉苁蓉 | Desertliving cistanche | Cistanche deserticola |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |