Compound Description

ID:   C0477 Common name:   Valproic Acid
IUPAC:  2-propylpentanoic acid CAS:  CAS:99-66-1
Chembl ID:   CHEMBL109 Pubchem ID:   CID:3121
Formula:  C8H16O2 TCM-ID:  TCMC2221
Smiles:  CCCC(C(=O)O)CCC
Alias:

Valeric acid, 2-propyl-;

2-Propylpentanoic acid;

2,2-Di-n-propylacetic acid;

2-Propylvaleric acid;

4-Heptanecarboxylic acid;

44089;

Acetic acid, dipropyl-;

DPA;

Depakine;

Depakine-chrono;

Dipropylacetic acid;

Ergenyl;

Mylproin;

NSC 93819;

Sigma V 0033000;

Stavzor;

Valcote;

Valproic acid;

n-Dipropylacetic acid
Structure:

Related Targets  (Total: 34)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T42D4V Histone deacetylase 1HDAC1 Q13547
A 7 Reference(s)
T68DAN Histone deacetylase 9HDAC9 Q9UKV0
A 13 Reference(s)
T90RVD Histone deacetylase 8HDAC8 Q9BY41
A 2 Reference(s)
T68M1D Histone deacetylase 2HDAC2 Q92769
A 2 Reference(s)
T38AWT Histone deacetylase 3HDAC3 O15379
A 1 Reference(s)
T82ALJ Glycogen synthase kinase-3 betaGSK3B P49841
A 1 Reference(s)
T18C4B Methylated-DNA--protein-cysteine methyltransferaseMGMT P16455
A 1 Reference(s)
T74LFK Neurogenic locus notch homolog protein 1NOTCH1 P46531
A 3 Reference(s)
T90FBZ ClusterinCLU P10909
A 1 Reference(s)
T83YZD AcetylcholinesteraseACHE P22303
A 1 Reference(s)
T42PUG Solute carrier family 2, facilitated glucose transporter member 1SLC2A1 P11166
C 1 Reference(s)
T49V5I Survival motor neuron proteinSMN1; SMN2 Q16637
C 3 Reference(s)
T02HSM NeuroglobinNGB Q9NPG2
C 1 Reference(s)
T71N8B Survival motor neuron proteinSMN1; SMN2 Q16637
C 1 Reference(s)
T23VMI Tumor necrosis factorTNF P01375
C 1 Reference(s)
T63T5P Histone deacetylase 4HDAC4 P56524
C 1 Reference(s)
T94H37 Cadherin-1CDH1 P12830
C 1 Reference(s)
T71B0A Cytosolic phospholipase A2PLA2G4A P47712
C 1 Reference(s)
T85QFY Somatostatin receptor type 2SSTR2 P30874
C 1 Reference(s)
T75GKT Mothers against decapentaplegic homolog 4SMAD4 Q13485
C 1 Reference(s)
T18YXD AlbuminALB P02768
C 1 Reference(s)
T74D4Y CASP8 and FADD-like apoptosis regulatorCFLAR O15519
C 1 Reference(s)
T06MXL NeprilysinMME P08473
C 1 Reference(s)
T51WGR Pancreas/duodenum homeobox protein 1PDX1 P52945
C 1 Reference(s)
T43N2D Epidermal growth factor receptorEGFR P00533
C 1 Reference(s)
T55LCD POU domain, class 5, transcription factor 1POU5F1 Q01860
C 1 Reference(s)
T61SU2 Coxsackievirus and adenovirus receptorCXADR P78310
C 1 Reference(s)
T04FNN Guanine nucleotide-binding protein G(i) subunit alpha-1GNAI1 P63096
C 1 Reference(s)
T12T4H Brain-derived neurotrophic factorBDNF P23560
C 2 Reference(s)
T40DE5 Tryptophan 2,3-dioxygenaseTDO2 P48775
C 1 Reference(s)
T36NQ9 Mothers against decapentaplegic homolog 1SMAD1 Q15797
C 1 Reference(s)
T64HY3 Mothers against decapentaplegic homolog 5SMAD5 Q99717
C 1 Reference(s)
T96OOK Signal transducer and activator of transcription 3STAT3 P40763
C 1 Reference(s)
T22QY0 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3BNIP3 Q12983
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens