HIT-result

Target Description

Type	Detail
Target ID	T04FNN
Protein Name	Guanine nucleotide-binding protein G(i) subunit alpha-1
Uniprot ID	P63096
Protein Name Alias	Adenylate cyclase-inhibiting G alpha protein
Gene ID	2770
Gene Symbol	GNAI1
Gene Alias	NA
TTD	NA
Pfam	PF00503
GO	0030168:platelet activation 0070062:extracellular exosome 0006457:protein folding 0043949:regulation of cAMP-mediated signaling 0007193:adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 0030496:midbody 0007186:G protein-coupled receptor signaling pathway 1904778:positive regulation of protein localization to cell cortex 0019003:GDP binding 0043434:response to peptide hormone 0031821:G protein-coupled serotonin receptor binding 0060236:regulation of mitotic spindle organization 0005886:plasma membrane 0000287:magnesium ion binding 0005765:lysosomal membrane 0050805:negative regulation of synaptic transmission 0001664:G protein-coupled receptor binding 0005737:cytoplasm 0007188:adenylate cyclase-modulating G protein-coupled receptor signaling pathway 0007049:cell cycle 0005834:heterotrimeric G-protein complex 0005634:nucleus 0032794:GTPase activating protein binding 0099738:cell cortex region 1904322:cellular response to forskolin 0045121:membrane raft 0031683:G-protein beta/gamma-subunit complex binding 0005525:GTP binding 0051301:cell division 0003924:GTPase activity 0005813:centrosome
PDB	6DDF ; 6XBK ; 2IK8 ; 6XBJ ; 6DDE ; 6OSA ; 6PT0 ; 6LML ; 2XNS ; 6VU8 ; 4G5Q ; 7L0Q ; 5JS7 ; 6XBM ; 6CMO ; 2G83 ; 6CRK ; 7L0S ; 5TDH ; 2OM2 ; 3ONW ; 2GTP ; 6KPG ; 6PB1 ; 6LFM ; 6XBL ; 6QNO ; 6N4B ; 5JS8 ; 6OS9 ; 3QI2 ; 1KJY ; 3QE0 ; 6KPF ; 6OT0 ; 3UMS ; 6LFO ; 6PB0 ; 7L0R ; 1Y3A ; 3UMR ; 7L0P ; 6OMM
Drugbank	DB04315 ; DB04444
KEGG	hsa:2770

Type

Detail

Target ID

T04FNN

Protein Name

Guanine nucleotide-binding protein G(i) subunit alpha-1

Uniprot ID

P63096

Protein Name Alias

Adenylate cyclase-inhibiting G alpha protein

Gene ID

2770

Gene Symbol

GNAI1

Gene Alias

TTD

Pfam

PF00503

0030168:platelet activation

0070062:extracellular exosome

0006457:protein folding

0043949:regulation of cAMP-mediated signaling

0007193:adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

0030496:midbody

0007186:G protein-coupled receptor signaling pathway

1904778:positive regulation of protein localization to cell cortex

0019003:GDP binding

0043434:response to peptide hormone

0031821:G protein-coupled serotonin receptor binding

0060236:regulation of mitotic spindle organization

0005886:plasma membrane

0000287:magnesium ion binding

0005765:lysosomal membrane

0050805:negative regulation of synaptic transmission

0001664:G protein-coupled receptor binding

0005737:cytoplasm

0007188:adenylate cyclase-modulating G protein-coupled receptor signaling pathway

0007049:cell cycle

0005834:heterotrimeric G-protein complex

0005634:nucleus

0032794:GTPase activating protein binding

0099738:cell cortex region

1904322:cellular response to forskolin

0045121:membrane raft

0031683:G-protein beta/gamma-subunit complex binding

0005525:GTP binding

0051301:cell division

0003924:GTPase activity

0005813:centrosome

PDB

6DDF ; 6XBK ; 2IK8 ; 6XBJ ; 6DDE ; 6OSA ; 6PT0 ; 6LML ; 2XNS ; 6VU8 ; 4G5Q ; 7L0Q ; 5JS7 ; 6XBM ; 6CMO ; 2G83 ; 6CRK ; 7L0S ; 5TDH ; 2OM2 ; 3ONW ; 2GTP ; 6KPG ; 6PB1 ; 6LFM ; 6XBL ; 6QNO ; 6N4B ; 5JS8 ; 6OS9 ; 3QI2 ; 1KJY ; 3QE0 ; 6KPF ; 6OT0 ; 3UMS ; 6LFO ; 6PB0 ; 7L0R ; 1Y3A ; 3UMR ; 7L0P ; 6OMM

Drugbank

DB04315 ; DB04444

KEGG

hsa:2770

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0427	Shan Zhu Yu	山茱萸	Asiatic cornelian cherry	Cornus officinalis
H0331	Qiang Huo	羌活	Incised notopterygium	Notopterygium incisum
H0746	Yin Chen Hao Gan Jin Gao	茵陈蒿干浸膏	Capillary wormwood	Artemisia capillaris
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0418	Shan Yin Chen	山茵陈	Capillary wormwood	Artemisia capillaris
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0224	Man Tuo Luo Ye	曼陀罗叶	Hindu datura leaf	Datura metel
H0225	Man Tuo Luo Zi	曼陀罗子	Hindu datura seed	Datura metel
H0085	Jiu Yu Rou	酒萸肉	Asiatic cornelian cherry	Cornus officinalis
H0720	Yang Jin Hua	洋金花	Hindu datura flower	Datura metel
H1183	Hong Dou	红豆	Hosie ormosia	Ormosia hosiei
H0217	Man Jing Zi	蔓荆子	Threeleaf chastetree fruit	Vitex trifolia
H0216	Man Jing Ye	蔓荆叶	Threeleaf chastetree leaf	Vitex trifolia
H0745	Yin Chen Hao	茵陈蒿	Capillary wormwood	Artemisia capillaris
H0881	Chuan Qiang Huo	川羌活	Incised notopterygium	Notopterygium incisum
H0585	Tu Yin Chen Hao	土茵陈蒿	Capillary wormwood	Artemisia capillaris

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 16)