Herb Description
| Herb ID: H0331 | Chinese Character: 羌活 |
| English Name: Incised notopterygium | Latin Name: Notopterygium incisum |
| Chinese Pin Yin : Qiang Huo | TCM-ID: TCMH1665 |
| Therapeutic Function in Chinese : 解表 | Therapeutic Function in English: For relieving exterior syndrome |
| Herb Function: Relieve pain and rheumatic conditions | |
Related Targets (Total: 96)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
2 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
3 Reference(s) |
| T77PFO | Histone deacetylase 6 | HDAC6 |
Q9UBN7 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
2 Reference(s) |
| T82GHD | Kit ligand | KITLG |
P21583 |
1 Reference(s) |
| T40XHY | Homeobox protein Hox-A1 | HOXA1 |
P49639 |
1 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T22BA6 | Macrophage colony-stimulating factor 1 | CSF1 |
P09603 |
1 Reference(s) |
| T53BUI | Pro-interleukin-16 [Cleaved into: Interleukin-16 | IL16 |
Q14005 |
1 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
2 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
3 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
5 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
2 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
2 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
4 Reference(s) |
| T68HNO | Glutathione S-transferase omega-1 | GSTO1 |
P78417 |
1 Reference(s) |
| T61LV9 | Free fatty acid receptor 3 | FFAR3 |
O14843 |
1 Reference(s) |
| T76MVQ | Free fatty acid receptor 4 | FFAR4 |
Q5NUL3 |
1 Reference(s) |
| T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
1 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
1 Reference(s) |
| T25RTY | C-C motif chemokine 22 | CCL22 |
O00626 |
1 Reference(s) |
| T77O2V | Mannose-1-phosphate guanyltransferase beta | GMPPB |
Q9Y5P6 |
1 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
| T75RAR | Dual oxidase 2 | DUOX2 |
Q9NRD8 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T64V6C | Glutamate decarboxylase 1 | GAD1 |
Q99259 |
1 Reference(s) |
| T83RKS | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | MGAT1 |
P26572 |
2 Reference(s) |
| T73PZA | Vesicular inhibitory amino acid transporter | SLC32A1 |
Q9H598 |
1 Reference(s) |
| T68XXK | 4-aminobutyrate aminotransferase, mitochondrial | ABAT |
P80404 |
4 Reference(s) |
| T35WLZ | Sodium- and chloride-dependent GABA transporter 3 | SLC6A11 |
P48066 |
2 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
1 Reference(s) |
| T41Z1X | Gamma-aminobutyric acid receptor-associated protein | GABARAP |
O95166 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
2 Reference(s) |
| T49WTT | Glycine N-methyltransferase | GNMT |
Q14749 |
1 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
1 Reference(s) |
| T30KQB | Alanine aminotransferase 1 | GPT |
P24298 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
| T46BLT | Protein-glutamine gamma-glutamyltransferase K | TGM1 |
P22735 |
1 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
1 Reference(s) |
| T94WHJ | Retinol-binding protein 4 | RBP4 |
P02753 |
2 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
1 Reference(s) |
| T39UT9 | Retinol-binding protein 1 | RBP1 |
P09455 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
| T36NQ9 | Mothers against decapentaplegic homolog 1 | SMAD1 |
Q15797 |
1 Reference(s) |
| T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
1 Reference(s) |
| T01HJQ | Calreticulin | CALR |
P27797 |
1 Reference(s) |
| T86J48 | Sodium/glucose cotransporter 1 | SLC5A1 |
P13866 |
2 Reference(s) |
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
2 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
1 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
| T82S6C | Hexokinase-4 | GCK |
P35557 |
1 Reference(s) |
| T18CPB | Choline O-acetyltransferase | CHAT |
P28329 |
1 Reference(s) |
| T04V7K | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 | ENPP7 |
Q6UWV6 |
1 Reference(s) |
| T51U9M | Carnitine O-palmitoyltransferase 1, muscle isoform | CPT1B |
Q92523 |
1 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
2 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
1 Reference(s) |
| T04FNN | Guanine nucleotide-binding protein G(i) subunit alpha-1 | GNAI1 |
P63096 |
1 Reference(s) |
| T21CMG | Hepcidin | HAMP |
P81172 |
1 Reference(s) |
| T82I7J | C-C motif chemokine 16 | CCL16 |
O15467 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
1 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T88P76 | DNA excision repair protein ERCC-1 | ERCC1 |
P07992 |
1 Reference(s) |
| T77OVM | Diablo homolog, mitochondrial | DIABLO |
Q9NR28 |
1 Reference(s) |
| T36SCD | NA | MIR107 |
NA |
1 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
2 Reference(s) |
| T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
2 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
| T89GCM | Inward rectifier potassium channel 2 | KCNJ2 |
P63252 |
1 Reference(s) |
| T90XYZ | C-reactive protein | CRP |
P02741 |
1 Reference(s) |
| T43Y5O | D(3) dopamine receptor | DRD3 |
P35462 |
1 Reference(s) |
| T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
| T74P7I | G-protein coupled bile acid receptor 1 | GPBAR1 |
Q8TDU6 |
1 Reference(s) |
| T68WYW | von Willebrand factor | VWF |
P04275 |
1 Reference(s) |
| T82S9G | DNA repair protein RAD51 homolog 1 | RAD51 |
Q06609 |
1 Reference(s) |
Related Compounds (Total: 16)
C0094
Name: Gamma-Aminobutyric Acid
C0416
Name: Stearic Acid
C0270
Name: Osthenol
C0366
Name: Retinol
C1258
Name: Coumaric Acid
key description of the interaction between compound and target