HIT-result

Type	Detail
Target ID	T82S9G
Protein Name	DNA repair protein RAD51 homolog 1
Uniprot ID	Q06609
Protein Name Alias	HsRAD51; hRAD51; RAD51 homolog A
Gene ID	5888
Gene Symbol	RAD51
Gene Alias	RAD51A; RECA
TTD	T63083: Clinical Trial target
Pfam	PF08423
GO	0070182:DNA polymerase binding 0000781:chromosome, telomeric region 0003690:double-stranded DNA binding 0001932:regulation of protein phosphorylation 0000150:recombinase activity 1904631:response to glucoside 0032991:protein-containing complex 0006974:cellular response to DNA damage stimulus 0009636:response to toxic substance 0007131:reciprocal meiotic recombination 0000793:condensed chromosome 0005524:ATP binding 0042493:response to drug 0000800:lateral element 0051321:meiotic cell cycle 0008022:protein C-terminus binding 0051106:positive regulation of DNA ligation 0071480:cellular response to gamma radiation 0000228:nuclear chromosome 0003682:chromatin binding 0042148:strand invasion 0006312:mitotic recombination 0006268:DNA unwinding involved in DNA replication 0010833:telomere maintenance via telomere lengthening 1990426:mitotic recombination-dependent replication fork processing 0017116:single-stranded DNA helicase activity 0042802:identical protein binding 0008094:DNA-dependent ATPase activity 0072719:cellular response to cisplatin 0003697:single-stranded DNA binding 0005654:nucleoplasm 0005815:microtubule organizing center 0019899:enzyme binding 0031297:replication fork processing 0005737:cytoplasm 0035861:site of double-strand break 0000724:double-strand break repair via homologous recombination 0048471:perinuclear region of cytoplasm 0036297:interstrand cross-link repair 0000722:telomere maintenance via recombination 0070192:chromosome organization involved in meiotic cell cycle 0005739:mitochondrion 0000785:chromatin 0016605:PML body 0000794:condensed nuclear chromosome 0071479:cellular response to ionizing radiation 0000730:DNA recombinase assembly 0005634:nucleus 0070317:negative regulation of G0 to G1 transition 0010569:regulation of double-strand break repair via homologous recombination 0006281:DNA repair 0005759:mitochondrial matrix 0072711:cellular response to hydroxyurea 1990414:replication-born double-strand break repair via sister chromatid exchange 0010165:response to X-ray 0072757:cellular response to camptothecin 0006310:DNA recombination
PDB	5JZC ; 5NWL ; 1B22 ; 5H1C ; 5H1B ; 1N0W ; 7C9A ; 5NP7
Drugbank	DB04395 ; DB12742
KEGG	hsa:5888

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H0937	Da Qing Ye	大青叶	Indigo-coloured woad leaf	Isatis indigotica
H0221	Bei Liu Ji Nu	北刘寄奴	‎Diverse wormwood herb	Herba artemisiae anomalae
H0405	Shan Dou Gen	山豆根	Tonkin sophora root	Sophora subprostrata
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0398	Sha Ren	砂仁	Villous amomum	Amomum villosum
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H1021	E Da Xia	莪大夏	NA	Oxytropis falcata
H1152	Bai Jie Zi	白芥子	White mustard seed	Sinapis alba
H0017	Ji Xue Teng	鸡血藤	Suberect spatholobus stem	Spatholobus suberectus
H1247	Huang Qi	黄芪	Membranous milkvetch	Astragalus membranaceus
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1248	Huang Qi Gan Jin Gao	黄芪干浸膏	Membranous milkvetch	Astragalus membranaceus
H0981	Dian Ji Xue Teng Gao Fen	滇鸡血藤膏粉	Suberect spatholobus stem	Spatholobus suberectus
H1007	Dou You	豆油	Soybean oil	Glycine max
H0137	Ban Lan Gen	板蓝根	Indigowoad root	Isatis indigotica
H0109	Ku Lian Zi	苦楝子	NA	Melia azedarach
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H0263	Mu Ban Lan Gen	木板蓝根	Indigowoad root	Isatis indigotica
H0019	Ji Xue Teng Gao	鸡血藤膏	Suberect spatholobus stem	Spatholobus suberectus
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0705	Yan Hu Lu Ba	盐胡芦巴	Fenugreek	Trigonella foenum-graecum
H1250	Huang Qi Ti Qu Ye	黄芪提取液	Membranous milkvetch	Astragalus membranaceus
H0551	Cang Zhu	苍术	Swordlike atractylodes	Atractylodes lancea
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0995	Dong Chong Xia Cao	冬虫夏草	Aweto	Cordyceps sinensis
H0018	Ji Xue Teng Gan Gao	鸡血藤干膏	Suberect spatholobus stem	Spatholobus suberectus
H0108	Ku Lian Pi	苦楝皮	Chinaberry-tree bark	Melia azedarach
H0265	Mu Da Qing Ye	木大青叶	Indigo-coloured woad leaf equivalent	Isatis indigotica
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0026	Jiang	姜	Soybean paste	Glycine max
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H0450	Shi Chang Pu	石菖蒲	Grassleaved sweetflag	Acorus tatarinowii
H0210	Mai Dong	麦冬	Liriope	Ophiopogon japonicus
H0331	Qiang Huo	羌活	Incised notopterygium	Notopterygium incisum
H1249	Huang Qi Jin Gao	黄芪浸膏	Membranous milkvetch	Astragalus membranaceus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0131	Ban Lan	板蓝	Indigowoad root	Isatis indigotica
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H0897	Chuan Lian	川楝	Chinaberry	Melia azedarach
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0709	Chang Shan	常山	Antifebrile dichroa	Dichroa febrifuga
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia
H1009	Du Huo	独活	Doubleteeth pubescent angelica	Angelica pubescens
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 58)