Herb ID: H0551 | Chinese Character: 苍术 |
English Name: Swordlike atractylodes | Latin Name: Atractylodes lancea |
Chinese Pin Yin : Cang Zhu | TCM-ID: TCMH211 |
Therapeutic Function in Chinese : 芳香化湿 | Therapeutic Function in English: For desolving dampness by flavors |
Herb Function: Remove damp and invigorate the function of the spleen, disple wind-cold, and improve eyesight |
Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
---|---|---|---|---|
T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
T13KGH | Tyrosinase | TYR |
P14679 |
2 Reference(s) |
T31MUM | 5,6-dihydroxyindole-2-carboxylic acid oxidase | TYRP1 |
P17643 |
1 Reference(s) |
T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
T85U8U | Caspase-3 | CASP3 |
P42574 |
14 Reference(s) |
T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
2 Reference(s) |
T62P0D | Collagenase 3 | MMP13 |
P45452 |
2 Reference(s) |
T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
13 Reference(s) |
T91OUC | Mucin-5AC | MUC5AC |
P98088 |
1 Reference(s) |
T31U13 | Cytochrome P450 2C19 | CYP2C19 |
P33261 |
1 Reference(s) |
T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
1 Reference(s) |
T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
2 Reference(s) |
T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
2 Reference(s) |
T15I0F | Proteasome activator complex subunit 1 | PSME1 |
Q06323 |
1 Reference(s) |
T44BWE | Adiponectin receptor protein 2 | ADIPOR2 |
Q86V24 |
1 Reference(s) |
T54CIF | Interleukin-8 | CXCL8 |
P10145 |
4 Reference(s) |
T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
2 Reference(s) |
T61SU2 | Coxsackievirus and adenovirus receptor | CXADR |
P78310 |
1 Reference(s) |
T23P74 | Caspase-9 | CASP9 |
P55211 |
5 Reference(s) |
T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
T30VNV | Myeloperoxidase | MPO |
P05164 |
4 Reference(s) |
T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
10 Reference(s) |
T74WWP | Peroxisome proliferator-activated receptor delta | PPARD |
Q03181 |
1 Reference(s) |
T14JSX | Plasminogen | PLG |
P00747 |
1 Reference(s) |
T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
6 Reference(s) |
T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
T67LRH | RNA-binding protein Musashi homolog 1 | MSI1 |
O43347 |
1 Reference(s) |
T51IKV | DNA topoisomerase 2-alpha | TOP2A |
P11388 |
1 Reference(s) |
T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
4 Reference(s) |
T32R5L | Cyclin-dependent kinase 9 | CDK9 |
P50750 |
2 Reference(s) |
T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
2 Reference(s) |
T62UOD | Serine/threonine-protein kinase VRK1 | VRK1 |
Q99986 |
1 Reference(s) |
T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
1 Reference(s) |
T60B3R | Glutathione S-transferase kappa 1 | GSTK1 |
Q9Y2Q3 |
1 Reference(s) |
T67CB6 | Transcriptional regulator ERG | ERG |
P11308 |
1 Reference(s) |
T39M6J | ATP-binding cassette sub-family C member 2 | ABCC2 |
Q92887 |
1 Reference(s) |
T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
1 Reference(s) |
T11NOZ | NA | MIR132 |
NA |
1 Reference(s) |
T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
1 Reference(s) |
T68DAN | Histone deacetylase 9 | HDAC9 |
Q9UKV0 |
1 Reference(s) |
T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
T91AIW | Receptor-type tyrosine-protein kinase FLT3 | FLT3 |
P36888 |
1 Reference(s) |
T25M2J | Anoctamin-1 | ANO1 |
Q5XXA6 |
1 Reference(s) |
T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
11 Reference(s) |
T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
1 Reference(s) |
T29B10 | Interleukin-17A | IL17A |
Q16552 |
1 Reference(s) |
T38O11 | Cyclin-G-associated kinase | GAK |
O14976 |
1 Reference(s) |
T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
1 Reference(s) |
T95LIF | Cannabinoid receptor 2 | CNR2 |
P34972 |
12 Reference(s) |
T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
T36NQ9 | Mothers against decapentaplegic homolog 1 | SMAD1 |
Q15797 |
1 Reference(s) |
T18LX5 | Neutrophil elastase | ELANE |
P08246 |
1 Reference(s) |
T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
1 Reference(s) |
T22H8P | Carbonic anhydrase 3 | CA3 |
P07451 |
1 Reference(s) |
T44LWL | Transcription factor p65 | RELA |
Q04206 |
2 Reference(s) |
T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
1 Reference(s) |
T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
7 Reference(s) |
T80OJF | Interstitial collagenase | MMP1 |
P03956 |
3 Reference(s) |
T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
9 Reference(s) |
T75HMM | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 |
Q07820 |
2 Reference(s) |
T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
2 Reference(s) |
T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
1 Reference(s) |
T02WX3 | RNA-binding protein FUS | FUS |
P35637 |
1 Reference(s) |
T12OUN | Myoglobin | MB |
P02144 |
1 Reference(s) |
T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
2 Reference(s) |
T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
1 Reference(s) |
T68BGR | Glial fibrillary acidic protein | GFAP |
P14136 |
1 Reference(s) |
T64X48 | C-X-C chemokine receptor type 4 | CXCR4 |
P61073 |
1 Reference(s) |
T08U92 | Mitochondrial brown fat uncoupling protein 1 | UCP1 |
P25874 |
1 Reference(s) |
T13WH4 | Interferon-induced, double-stranded RNA-activated protein kinase | EIF2AK2 |
P19525 |
1 Reference(s) |
T61OY3 | UDP-glucuronosyltransferase 1A1 | UGT1A1 |
P22309 |
1 Reference(s) |
T30W5B | UDP-glucuronosyltransferase 1-6 | UGT1A6 |
P19224 |
1 Reference(s) |
T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
10 Reference(s) |
T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
T39YFG | Trypsin-1 | PRSS1 |
P07477 |
1 Reference(s) |
T54WR0 | Fatty acid-binding protein 5 | FABP5 |
Q01469 |
1 Reference(s) |
T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
2 Reference(s) |
T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
2 Reference(s) |
T07S0E | BDNF/NT-3 growth factors receptor | NTRK2 |
Q16620 |
1 Reference(s) |
T90XYZ | C-reactive protein | CRP |
P02741 |
1 Reference(s) |
T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
1 Reference(s) |
T89L4V | Insulin | INS |
P01308 |
1 Reference(s) |
T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
T23YZF | Peptidyl-glycine alpha-amidating monooxygenase | PAM |
P19021 |
1 Reference(s) |
T77FOL | Neuromodulin | GAP43 |
P17677 |
1 Reference(s) |
T93VFT | Endothelin-1 | EDN1 |
P05305 |
2 Reference(s) |
T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 |
P05121 |
1 Reference(s) |
T02DEN | Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide | GCG |
P01275 |
1 Reference(s) |
T48UT8 | Cholesteryl ester transfer protein | CETP |
P11597 |
1 Reference(s) |
T32HPO | Aspartyl aminopeptidase | DNPEP |
Q9ULA0 |
1 Reference(s) |
T20H9F | Stromelysin-1 | MMP3 |
P08254 |
2 Reference(s) |
T02YLA | Alpha-lactalbumin | LALBA |
P00709 |
1 Reference(s) |
T34DZ7 | Interleukin-2 | IL2 |
P60568 |
1 Reference(s) |
T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
1 Reference(s) |
T99XQ3 | DNA topoisomerase 1 | TOP1 |
P11387 |
1 Reference(s) |
T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
2 Reference(s) |
T14LSK | E3 ubiquitin-protein ligase XIAP | XIAP |
P98170 |
1 Reference(s) |
T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
2 Reference(s) |
T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
3 Reference(s) |
T33OPP | Interleukin-6 | IL6 |
P05231 |
6 Reference(s) |
T26KIE | Transcription factor AP-1 | JUN |
P05412 |
5 Reference(s) |
T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
5 Reference(s) |
T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
6 Reference(s) |
T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
2 Reference(s) |
T47HTN | Prostaglandin E synthase | PTGES |
O14684 |
1 Reference(s) |
T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
P04626 |
2 Reference(s) |
T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
4 Reference(s) |
T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
4 Reference(s) |
T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
2 Reference(s) |
T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
3 Reference(s) |
T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
1 Reference(s) |
T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
1 Reference(s) |
T06PVX | E3 ubiquitin-protein ligase Mdm2 | MDM2 |
Q00987 |
1 Reference(s) |
T92AMR | Hepatocyte growth factor receptor | MET |
P08581 |
1 Reference(s) |
T23VMI | Tumor necrosis factor | TNF |
P01375 |
8 Reference(s) |
T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
4 Reference(s) |
T69NG6 | Interleukin-10 | IL10 |
P22301 |
2 Reference(s) |
T37VLU | Interferon gamma | IFNG |
P01579 |
1 Reference(s) |
T88B8X | Insulin receptor | INSR |
P06213 |
1 Reference(s) |
T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
1 Reference(s) |
T60GGR | Serine/threonine-protein kinase TBK1 | TBK1 |
Q9UHD2 |
1 Reference(s) |
T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
1 Reference(s) |
T01E7W | Aurora kinase B | AURKB |
Q96GD4 |
1 Reference(s) |
T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
2 Reference(s) |
T62Y4H | Protein kinase C epsilon type | PRKCE |
Q02156 |
1 Reference(s) |
T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
T35LKG | Adenosine receptor A1 | ADORA1 |
P30542 |
1 Reference(s) |
T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
T36YWU | Kelch-like ECH-associated protein 1 | KEAP1 |
Q14145 |
1 Reference(s) |
T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
T88P76 | DNA excision repair protein ERCC-1 | ERCC1 |
P07992 |
1 Reference(s) |
T77OVM | Diablo homolog, mitochondrial | DIABLO |
Q9NR28 |
1 Reference(s) |
T36SCD | NA | MIR107 |
NA |
1 Reference(s) |
T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
1 Reference(s) |
T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
2 Reference(s) |
T73HMK | Bcl-2-binding component 3, isoforms 1/2 | BBC3 |
Q9BXH1 |
1 Reference(s) |
T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
2 Reference(s) |
T00CXT | Prostaglandin G/H synthase 1 | PTGS1 |
P23219 |
1 Reference(s) |
T04WT7 | Fibronectin | FN1 |
P02751 |
1 Reference(s) |
T17CZC | Tissue factor | F3 |
P13726 |
2 Reference(s) |
T67UWO | C-C motif chemokine 26 | CCL26 |
Q9Y258 |
1 Reference(s) |
T02IOG | Cyclin-dependent kinase inhibitor 1B | CDKN1B |
P46527 |
2 Reference(s) |
T67LQK | Mitogen-activated protein kinase 11 (MAP kinase 11) (MAPK 11) (EC 2.7.11.24) (Mitogen-activated protein kinase p38 beta) (MAP kinase p38 beta) (p38b) (Stress-activated protein kinase 2b) (SAPK2b) (p38-2) | MAPK11 |
Q15759 |
1 Reference(s) |
T93PLN | Serine/threonine-protein kinase/endoribonuclease IRE1 | ERN1 |
O75460 |
1 Reference(s) |
T74D4Y | CASP8 and FADD-like apoptosis regulator | CFLAR |
O15519 |
1 Reference(s) |
T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
2 Reference(s) |
T50VJF | Osteopontin | SPP1 |
P10451 |
1 Reference(s) |
T53KRS | E3 ubiquitin-protein ligase NEDD4-like | NEDD4L |
Q96PU5 |
1 Reference(s) |
T38G9K | TNF receptor-associated factor 2 | TRAF2 |
Q12933 |
1 Reference(s) |
T95A39 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | UCHL1 |
P09936 |
1 Reference(s) |
T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
1 Reference(s) |
T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
T32W5X | Type-2 angiotensin II receptor | AGTR2 |
P50052 |
1 Reference(s) |
T66JU3 | 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | SRD5A2 |
P31213 |
1 Reference(s) |
T75B9S | Cyclic AMP-responsive element-binding protein 1 | CREB1 |
P16220 |
1 Reference(s) |
T92WFW | C-C motif chemokine 3 | CCL3 |
P10147 |
1 Reference(s) |
T96N1K | Calcium/calmodulin-dependent protein kinase type IV | CAMK4 |
Q16566 |
1 Reference(s) |
T27S6H | Pulmonary surfactant-associated protein B | SFTPB |
P07988 |
1 Reference(s) |
T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 |
P16284 |
1 Reference(s) |
T19BO9 | Bone morphogenetic protein 4 | BMP4 |
P12644 |
1 Reference(s) |
T34AW3 | Lipopolysaccharide-binding protein | LBP |
P18428 |
1 Reference(s) |
T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
T67RBZ | Mitochondrial uncoupling protein 2 | UCP2 |
P55851 |
1 Reference(s) |
T67HYX | Mitochondrial uncoupling protein 3 | UCP3 |
P55916 |
1 Reference(s) |
T19EKF | Cholecystokinin | CCK |
P06307 |
1 Reference(s) |
T19XSL | Fatty acid-binding protein, liver | FABP1 |
P07148 |
1 Reference(s) |
T23APZ | Retinol-binding protein 2 | RBP2 |
P50120 |
1 Reference(s) |
T03NWF | Sterol O-acyltransferase 1 | SOAT1 |
P35610 |
1 Reference(s) |
T48YPL | Aquaporin-3 | AQP3 |
Q92482 |
1 Reference(s) |
T53SLQ | Aquaporin-9 | AQP9 |
O43315 |
1 Reference(s) |
T75EH8 | Glucagon-like peptide 1 receptor | GLP1R |
P43220 |
1 Reference(s) |
T52VL6 | Signal transducer and activator of transcription 5A | STAT5A |
P42229 |
1 Reference(s) |
T19K8W | Signal transducer and activator of transcription 5B | STAT5B |
P51692 |
1 Reference(s) |
T68AKE | Zinc fingers and homeoboxes protein 2 | ZHX2 |
Q9Y6X8 |
1 Reference(s) |
T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
1 Reference(s) |
T10K5R | NA | MIR203A |
NA |
1 Reference(s) |
T66WWM | Claudin-2 | CLDN2 |
P57739 |
2 Reference(s) |
T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
1 Reference(s) |
T92HNO | High mobility group protein B1 | HMGB1 |
P09429 |
1 Reference(s) |
T01QLH | Estrogen receptor | ESR1 |
P03372 |
1 Reference(s) |
T78IOY | Telomerase reverse transcriptase | TERT |
O14746 |
1 Reference(s) |
T41BXR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | SIRT3 |
Q9NTG7 |
1 Reference(s) |
T41DXP | Pleiotrophin | PTN |
P21246 |
1 Reference(s) |
T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
T62RLH | NA | MIR384 |
NA |
1 Reference(s) |
T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
T41TXS | Retinoblastoma-associated protein | RB1 |
P06400 |
2 Reference(s) |
T70B7U | Angiotensin-converting enzyme 2 | ACE2 |
Q9BYF1 |
1 Reference(s) |
T64BTV | Interleukin-1 beta | IL1B |
P01584 |
2 Reference(s) |
T82S9G | DNA repair protein RAD51 homolog 1 | RAD51 |
Q06609 |
1 Reference(s) |
T48TW0 | Platelet glycoprotein 4 | CD36 |
P16671 |
1 Reference(s) |