Target Description

Type Detail
Target ID T32W5X
Protein Name Type-2 angiotensin II receptor
Uniprot ID P50052
Protein Name Alias Angiotensin II type-2 receptor;  AT2
Gene ID 186
Gene Symbol AGTR2
Gene Alias NA
TTD T09909: Successful target
Pfam PF00001
GO
0008134:transcription factor binding

0090190:positive regulation of branching involved in ureteric bud morphogenesis

0043537:negative regulation of blood vessel endothelial cell migration

0007263:nitric oxide mediated signal transduction

0035556:intracellular signal transduction

0007420:brain development

0007199:G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger

0001991:regulation of systemic arterial blood pressure by circulatory renin-angiotensin

0032516:positive regulation of phosphoprotein phosphatase activity

0008284:positive regulation of cell population proliferation

0042416:dopamine biosynthetic process

0005887:integral component of plasma membrane

0061049:cell growth involved in cardiac muscle cell development

0042311:vasodilation

0042306:regulation of protein import into nucleus

0035932:aldosterone secretion

0032304:negative regulation of icosanoid secretion

0005886:plasma membrane

0021695:cerebellar cortex development

0048471:perinuclear region of cytoplasm

0060993:kidney morphogenesis

0051387:negative regulation of neurotrophin TRK receptor signaling pathway

0006883:cellular sodium ion homeostasis

0010700:negative regulation of norepinephrine secretion

0030308:negative regulation of cell growth

0001974:blood vessel remodeling

0004930:G protein-coupled receptor activity

0035815:positive regulation of renal sodium excretion

0006954:inflammatory response

0004945:angiotensin type II receptor activity

0010459:negative regulation of heart rate

0048019:receptor antagonist activity

0007186:G protein-coupled receptor signaling pathway

0008217:regulation of blood pressure

0002018:renin-angiotensin regulation of aldosterone production

0007166:cell surface receptor signaling pathway

2001238:positive regulation of extrinsic apoptotic signaling pathway

0071549:cellular response to dexamethasone stimulus

0045429:positive regulation of nitric oxide biosynthetic process

0051000:positive regulation of nitric-oxide synthase activity

0048147:negative regulation of fibroblast proliferation

PDB 5UNG ; 6JOD ; 5UNH ; 5UNF
Drugbank DB01349 ; DB05739
KEGG hsa:186

Related Compounds  (Total: 2)

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C0300
Name: Phenol
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C0907
Name: Angiotensin Ii


Related Herbs  (Total: 37)

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H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H1203 Hu Ji Sheng槲寄生 Colored mistletoeViscum coloratum
H0772 Yue Ji Hua月季花 Chinese roseRosa chinensis
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0327 Qian Li Guang千里光 Climbing groundselSenecio scandens
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H1124 Guang Jin Qian Cao广金钱草 Snowbellleaf tickcloverDesmodium styracifolium
H1171 He Zi Rou诃子肉 Medicine terminaliaTerminalia chebula
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0216 Man Jing Ye蔓荆叶 Threeleaf chastetree leafVitex trifolia
H0152 Ling Zhi Jin Gao灵芝浸膏 NAGanoderma lucidum
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H0078 Jiu Bi Ying救必应 Ovateleaf hollyIlex rotunda
H1029 Fang Er Cha方儿茶 khair in hindiSenegalia catechu
H0565 Tu Bie Chong土鳖虫 CockroachEupolyphaga sinensis
H0446 Sheng Jiang生姜 Fresh common gingerZingiber officinale
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0547 Cang Qing Guo藏青果 MyrobalanTerminalia chebula
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0181 Luo Bu Ma罗布麻 DogbaneApocynum venetum
H0894 Chuan Xu Duan川续断 Himalayan teaselDipsacus asperoides
H0153 Ling Zhi(1)灵芝 Lucid ganodermaGanoderma lucidum
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H1170 He Zi诃子 Medicine terminaliaTerminalia chebula
H0551 Cang Zhu苍术 Swordlike atractylodesAtractylodes lancea
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0217 Man Jing Zi蔓荆子 Threeleaf chastetree fruitVitex trifolia