Target Description

Type Detail
Target ID T70B7U
Protein Name Angiotensin-converting enzyme 2
Uniprot ID Q9BYF1
Protein Name Alias EC 3.4.17.23;  Angiotensin-converting enzyme homolog;  ACEH;  Angiotensin-converting enzyme-related carboxypeptidase;  ACE-related carboxypeptidase;  EC 3.4.17.-;  Metalloprotease MPROT15
Gene ID 59272
Gene Symbol ACE2
Gene Alias NA
TTD T27889: Clinical Trial target
Pfam PF16959 ; PF01401
GO
0051957:positive regulation of amino acid transport

0070062:extracellular exosome

0003051:angiotensin-mediated drinking behavior

2000379:positive regulation of reactive oxygen species metabolic process

0060452:positive regulation of cardiac muscle contraction

0005615:extracellular space

0009986:cell surface

0016021:integral component of membrane

1903598:positive regulation of gap junction assembly

0046813:receptor-mediated virion attachment to host cell

0004181:metallocarboxypeptidase activity

0046718:viral entry into host cell

0004180:carboxypeptidase activity

0001618:virus receptor activity

0042802:identical protein binding

0005576:extracellular region

0002003:angiotensin maturation

0097746:blood vessel diameter maintenance

0001817:regulation of cytokine production

0005886:plasma membrane

2000272:negative regulation of signaling receptor activity

1903779:regulation of cardiac conduction

0008241:peptidyl-dipeptidase activity

0006508:proteolysis

0019229:regulation of vasoconstriction

0008270:zinc ion binding

0031526:brush border membrane

0004175:endopeptidase activity

0045121:membrane raft

0008237:metallopeptidase activity

1905737:positive regulation of L-proline import across plasma membrane

0015827:tryptophan transport

0005788:endoplasmic reticulum lumen

0042127:regulation of cell population proliferation

0003081:regulation of systemic arterial blood pressure by renin-angiotensin

0030666:endocytic vesicle membrane

0016324:apical plasma membrane

0022898:regulation of transmembrane transporter activity

0050727:regulation of inflammatory response

PDB 6VW1 ; 7JVO ; 7A94 ; 3D0G ; 7KMB ; 7A97 ; 6M17 ; 7KMZ ; 6M0J ; 6M18 ; 7KNH ; 6ACK ; 7A98 ; 7A92 ; 3SCL ; 7KNB ; 7KJ3 ; 3SCK ; 6ACG ; 7CT5 ; 7A91 ; 7KJ4 ; 7KNI ; 3SCJ ; 2AJF ; 7DF4 ; 1R42 ; 7KJ2 ; 3SCI ; 1XJP ; 6M1D ; 7DMU ; 7KMS ; 3D0I ; 7KNE ; 6CS2 ; 3KBH ; 7A96 ; 6ACJ ; 7A95 ; 1R4L ; 6LZG ; 3D0H
Drugbank DB00608 ; DB01611 ; DB15643 ; DB05203
KEGG hsa:59272

Related Compounds  (Total: 4)

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C0053
Name: Esculetin
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C0363
Name: Resveratrol
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C0948
Name: aldosterone
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C1017
Name: puerarin


Related Herbs  (Total: 100)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H1227 Huai Zhi槐枝 NASophora japonica
H1089 Gang Ren Zi岗稔子 rose myrtleRhodomyrtus tomentosa
H1015 Du Zhong杜仲 EucommiaEucommia ulmoides
H0226 Man Yue Mei蔓越莓 CranberryVaccinium oxycoccos
H1128 Bai Jiang败酱 Whiteflower patriniaPatrinia villosa
H0926 Da Huang大黄 Medicinal rhubarbRheum officinale
H0745 Yin Chen Hao茵陈蒿 Capillary wormwoodArtemisia capillaris
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H0802 Zhi Geng枳梗 NACitrus aurantium
H0551 Cang Zhu苍术 Swordlike atractylodesAtractylodes lancea
H1056 Fu Pen Zi覆盆子 Red-and-Yellow garden raspberryRubus idaeus
H0804 Zhi Ke枳壳 Seville ora nge unripe fruitCitrus aurantium
H0541 Cang Qie Gen藏茄根 Tibetan eggplant rootAnisodus tanguticus
H0357 Ren Shen人参 GinsengPanax ginseng
H1073 Gan Cao Jie甘草节 Glycyrrhiza uralensis fischGlycyrrhiza uralensis
H0805 Zhi Ke Gan Jin Gao枳壳干浸膏 Seville ora nge unripe fruitCitrus aurantium
H0758 Cheng Pi橙皮 Bitter orangeCitrus aurantium
H0015 Ji Xing Zi急性子 Garden balsam seedImpatiens balsamina
H1201 Hu Er Cao虎耳草 Creeping rockfoilSaxifraga stolonifera
H0139 Lian Qiao连翘 Weeping forsythiaForsythia suspensa
H0240 Mi Gan Cao蜜甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0927 Da Huang Jin Gao大黄浸膏 Medicinal rhubarbRheum officinale
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0613 Wu Yue Ai五月艾 ArtemisiaArtemisia princeps
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H1166 He Shou Wu何首乌 Tuber fleeceflowerPolygonum multiflorum
H0154 Ai Ye You艾叶油 Argy wormwood leafArtemisia argyi
H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H0571 Tu Gan Cao土甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0273 Mu Tong木通 Fiveleaf akebiaAkebia quinata
H1222 Huai Hua槐花 flower bud of japanese pagodatreeSophora japonica
H1075 Gan Cao Liu Jin Gao甘草流浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0103 Ai Ye艾叶 Argy wormwood leafArtemisia argyi
H1072 Gan Cao Gao甘草膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1224 Huai Jiao槐角 pod of japanese pagodatreeSophora japonica
H0617 Qian Cao Teng茜草藤 NARubia cordifolia
H1046 Feng Xian Tou Gu Cao凤仙透骨草 Spotted snapweedImpatiens balsamina
H0988 Ding Gong Teng丁公藤 Obtuseleaf Erycibe StemErycibe obtusifolia
H0614 Wu Zhao Long五爪龙 Cairo morninggloryIpomoea cairica
H0413 Shan Lang Dang山莨菪 NAAnisodus tanguticus
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H0418 Shan Yin Chen山茵陈 Capillary wormwoodArtemisia capillaris
H1138 Bai Jiang Cao败酱草 All - grass of dahurian patriniaThlaspi arvense
H0612 Cao Shan Hu Jin Gao草珊瑚浸膏 NASarcandra glabra
H1066 Gan Cao甘草 Glycyrrhiza inflataGlycyrrhiza uralensis
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0416 Shan Shen山参 NAPanax ginseng
H1016 Du Zhong Tan杜仲炭 EucommiaEucommia ulmoides
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H1067 Gan Cao Fen甘草粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H0095 Gou Qi Zi枸杞子 Chinese wolfberry fruitLycium chinense
H0094 Gou Qi枸杞 Chinese wolfberry fruitLycium chinense
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1017 Du Zhong Ye杜仲叶 Eucommia leafEucommia ulmoides
H1188 Hong Hua红花 SafflowerCarthamus tinctorius
H0434 She Pu Tao蛇葡萄 AmpelopsisAmpelopsis brevipedunculata
H0928 Da Huang Liu Jin Gao大黄流浸膏 Medicinal rhubarbRheum officinale
H0270 Mu Hu Die木蝴蝶 Indian trumpetflowerOroxylum indicum
H0432 She Gan射干 BlackberrylilyBelamcanda chinensis
H1045 Feng Xian Hua凤仙花 Spotted snapweedImpatiens balsamina
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0358 Ren Shen Ye人参叶 Ginseng leafPanax ginseng
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0536 Tian Di Ding甜地丁 Manyflower gueldenstaedtid herbViola philippica
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H1074 Gan Cao Jin Gao甘草浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H1070 Gan Cao Gan Gao Fen甘草干膏粉 Glycyrrhiza inflataGlycyrrhiza uralensis
H1220 Hua Xiang Shu Guo化香树果 NAPlatycarya strobilacea
H1213 Hu Zhang虎杖 Japanese fleeceflowerPolygonum cuspidatum
H1225 Huai Mi槐米 NASophora japonica
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H0472 Shu Da Huang熟大黄 NARheum palmatum
H0626 Xi Nan Huang Qin西南黄芩 Yunnan skullcapScutellaria amoena
H0883 Chuan She Gan川射干 BlackberrylilyBelamcanda chinensis
H1069 Gan Cao Gan Gao甘草干膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H0765 Chi Dou赤豆 Assuki beanVigna angularis
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0428 Shang Lu商陆 Indian pokeweedPhytolacca esculenta
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H1071 Gan Cao Gan Jin Gao甘草干浸膏 Glycyrrhiza inflataGlycyrrhiza uralensis
H1221 Hua Xiang Shu Guo Xu化香树果序 NAPlatycarya strobilacea
H0335 Qin Pi秦皮 bark of largeleaf chinese ashCortex fraxini
H0585 Tu Yin Chen Hao土茵陈蒿 Capillary wormwoodArtemisia capillaris
H0325 Qian Jin Zi千金子 Caper euphorbia seedEuphorbia lathyris
H1117 Guan Zhong贯众 Male fern rhizomeDryopteris crassirhizoma
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0083 Jiu Jie Cha九节茶 Glabrous sarcandraSarcandra glabra
H0746 Yin Chen Hao Gan Jin Gao茵陈蒿干浸膏 Capillary wormwoodArtemisia capillaris
H0528 Tao Jin Niang Gen桃金娘根 Downy rosemyrtle rootRhodomyrtus tomentosa
H0640 Xiang Fu香附 Nutgrass galingaleCyperus rotundus
H0813 Zhi Shi枳实 Seville orange young fruitCitrus aurantium
H0444 Sheng Gan Cao生甘草 Glycyrrhiza inflataGlycyrrhiza uralensis