Herb Description
| Herb ID: H0325 | Chinese Character: 千金子 |
| English Name: Caper euphorbia seed | Latin Name: Euphorbia lathyris |
| Chinese Pin Yin : Qian Jin Zi | TCM-ID: TCMH1658 |
| Therapeutic Function in Chinese : 泻下 | Therapeutic Function in English: Purging |
| Herb Function: Cause drastic purgation for treating edema, and eliminate blood stasis for treating masses | |
Related Targets (Total: 41)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T68OIU | CREB-regulated transcription coactivator 1 | CRTC1 |
Q6UUV9 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
3 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
7 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
2 Reference(s) |
| T40TBX | Aromatic-L-amino-acid decarboxylase | DDC |
P20711 |
1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
3 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
2 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
1 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
1 Reference(s) |
| T36YWU | Kelch-like ECH-associated protein 1 | KEAP1 |
Q14145 |
1 Reference(s) |
| T56MD7 | Glutathione hydrolase 5 proenzyme | GGT5 |
P36269 |
1 Reference(s) |
| T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
1 Reference(s) |
| T48J1U | Aldo-keto reductase family 1 member C1 | AKR1C1 |
Q04828 |
1 Reference(s) |
| T46AQJ | Glutathione S-transferase P | GSTP1 |
P09211 |
1 Reference(s) |
| T53QS9 | Glutamate--cysteine ligase catalytic subunit | GCLC |
P48506 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
1 Reference(s) |
| T12BGL | Cytochrome P450 2A6 | CYP2A6 |
P11509 |
1 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T48ZIG | D(2) dopamine receptor | DRD2 |
P14416 |
1 Reference(s) |
| T51K6D | Tyrosine-protein phosphatase non-receptor type 11 | PTPN11 |
Q06124 |
1 Reference(s) |
| T36RGT | Protein phosphatase 1 regulatory subunit 1B | PPP1R1B |
Q9UD71 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T43Y5O | D(3) dopamine receptor | DRD3 |
P35462 |
1 Reference(s) |
| T56RMM | DNA | DNMT3A |
Q9Y6K1 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
1 Reference(s) |
| T41TXS | Retinoblastoma-associated protein | RB1 |
P06400 |
1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T70B7U | Angiotensin-converting enzyme 2 | ACE2 |
Q9BYF1 |
1 Reference(s) |
| T62F1Y | Glutathione S-transferase A2 | GSTA2 |
P09210 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
1 Reference(s) |
Related Compounds (Total: 6)
C0054
Name: Esculin
C0179
Name: Levodopa
C1284
Name: Daphnetin
C1178
Name: Beta-Sitosterol
C0053
Name: Esculetin
key description of the interaction between compound and target