HIT-result

Type	Detail
Target ID	T40TBX
Protein Name	Aromatic-L-amino-acid decarboxylase
Uniprot ID	P20711
Protein Name Alias	AADC; EC 4.1.1.28; DOPA decarboxylase; DDC
Gene ID	1644
Gene Symbol	DDC
Gene Alias	AADC
TTD	T62193: Successful target
Pfam	PF00282
GO	0070062:extracellular exosome 0071312:cellular response to alkaloid 0035690:cellular response to drug 0019904:protein domain specific binding 0030424:axon 0016597:amino acid binding 0043025:neuronal cell body 0006584:catecholamine metabolic process 0046684:response to pyrethroid 0005829:cytosol 0030170:pyridoxal phosphate binding 0042427:serotonin biosynthetic process 0016831:carboxy-lyase activity 0052314:phytoalexin metabolic process 0019899:enzyme binding 0046219:indolalkylamine biosynthetic process 0042416:dopamine biosynthetic process 0010259:multicellular organism aging 0005737:cytoplasm 0015842:aminergic neurotransmitter loading into synaptic vesicle 0006520:cellular amino acid metabolic process 0004058:aromatic-L-amino-acid decarboxylase activity 0042423:catecholamine biosynthetic process 0036467:5-hydroxy-L-tryptophan decarboxylase activity 0071363:cellular response to growth factor stimulus 0033076:isoquinoline alkaloid metabolic process 0007623:circadian rhythm 0036468:L-dopa decarboxylase activity 0008021:synaptic vesicle
PDB	3RBL ; 3RCH ; 3RBF
Drugbank	DB00114 ; DB00260 ; DB00968 ; DB00190 ; DB00915 ; DB00875 ; DB13848 ; DB06262 ; DB01235 ; DB00150 ; DB12783
KEGG	hsa:1644

Go to browser

Name: Levodopa

Go to browser

Name: Anonaine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H1196	Hou Pu	厚朴	bark of officinal magnolia	Cortex magnoliae officinalis
H0325	Qian Jin Zi	千金子	Caper euphorbia seed	Euphorbia lathyris
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens