HIT-result

Target Description

Type	Detail
Target ID	T66JU3
Protein Name	3-oxo-5-alpha-steroid 4-dehydrogenase 2
Uniprot ID	P31213
Protein Name Alias	EC 1.3.1.22; 5 alpha-SR2; SR type 2; Steroid 5-alpha-reductase 2; S5AR 2; Type II 5-alpha reductase
Gene ID	6716
Gene Symbol	SRD5A2
Gene Alias	NA
TTD	T71390: Successful target
Pfam	PF02544
GO	0016491:oxidoreductase activity 0009917:sterol 5-alpha reductase activity 0007267:cell-cell signaling 0030539:male genitalia development 0016021:integral component of membrane 0047751:cholestenone 5-alpha-reductase activity 0006694:steroid biosynthetic process 0005789:endoplasmic reticulum membrane 0030154:cell differentiation 0061370:testosterone biosynthetic process 0006702:androgen biosynthetic process 0030283:testosterone dehydrogenase [NAD(P)] activity 0008209:androgen metabolic process 0003865:3-oxo-5-alpha-steroid 4-dehydrogenase activity 0008584:male gonad development
PDB	7BW1
Drugbank	DB13943 ; DB01126 ; DB01420 ; DB00548 ; DB01216 ; DB00421 ; DB13944 ; DB13946 ; DB00741 ; DB00717
KEGG	hsa:6716

Type

Detail

Target ID

T66JU3

Protein Name

3-oxo-5-alpha-steroid 4-dehydrogenase 2

Uniprot ID

P31213

Protein Name Alias

EC 1.3.1.22; 5 alpha-SR2; SR type 2; Steroid 5-alpha-reductase 2; S5AR 2; Type II 5-alpha reductase

Gene ID

6716

Gene Symbol

SRD5A2

Gene Alias

TTD

T71390: Successful target

Pfam

PF02544

0016491:oxidoreductase activity

0009917:sterol 5-alpha reductase activity

0007267:cell-cell signaling

0030539:male genitalia development

0016021:integral component of membrane

0047751:cholestenone 5-alpha-reductase activity

0006694:steroid biosynthetic process

0005789:endoplasmic reticulum membrane

0030154:cell differentiation

0061370:testosterone biosynthetic process

0006702:androgen biosynthetic process

0030283:testosterone dehydrogenase [NAD(P)] activity

0008209:androgen metabolic process

0003865:3-oxo-5-alpha-steroid 4-dehydrogenase activity

0008584:male gonad development

PDB

7BW1

Drugbank

DB13943 ; DB01126 ; DB01420 ; DB00548 ; DB01216 ; DB00421 ; DB13944 ; DB13946 ; DB00741 ; DB00717

KEGG

hsa:6716

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0104	Bai Zhu	白术	Largehead atractylodes	Atractylodes macrocephala
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0518	Suo Sha Ren	缩砂仁	Villous amomum fruit	Fructus amomi
H1173	Hei Chou	黑丑	Pharbitis seed	Semen pharbitidis
H0524	Tan Xiang	檀香	Sandalwood	Santalum album
H0399	Sha Ren Ye	砂仁叶	NA	Amomum villosum
H0071	Bai Ye	柏叶	Chinese arborvitae twig	Platycladus orientalis
H1214	Hua Jiao	花椒	Bunge pricklyash	Zanthoxylum bungeanum
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0613	Wu Yue Ai	五月艾	Artemisia	Artemisia princeps
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H1198	Hou Tou Jun	猴头菌	Bearded tooth carpophore	Hericium erinaceus
H0551	Cang Zhu	苍术	Swordlike atractylodes	Atractylodes lancea
H1011	Bai Chou	白丑	Pharbitis seed	Semen pharbitidis
H0416	Shan Shen	山参	NA	Panax ginseng
H0398	Sha Ren	砂仁	Villous amomum	Amomum villosum

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 21)