HIT-result

Type	Detail
Target ID	T64HY3
Protein Name	Mothers against decapentaplegic homolog 5
Uniprot ID	Q99717
Protein Name Alias	MAD homolog 5; Mothers against DPP homolog 5; JV5-1; SMAD family member 5; SMAD 5; Smad5; hSmad5
Gene ID	4090
Gene Symbol	SMAD5
Gene Alias	MADH5
TTD	NA
Pfam	PF03165 ; PF03166
GO	0005634:nucleus 0030509:BMP signaling pathway 0001880:Mullerian duct regression 0071144:heteromeric SMAD protein complex 0007179:transforming growth factor beta receptor signaling pathway 0005829:cytosol 0060048:cardiac muscle contraction 0030218:erythrocyte differentiation 0031625:ubiquitin protein ligase binding 0001657:ureteric bud development 0009653:anatomical structure morphogenesis 0017151:DEAD/H-box RNA helicase binding 0051216:cartilage development 0005737:cytoplasm 0071407:cellular response to organic cyclic compound 0030154:cell differentiation 0060348:bone development 0070411:I-SMAD binding 0009880:embryonic pattern specification 0000785:chromatin 0002051:osteoblast fate commitment 1901522:positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 0030514:negative regulation of BMP signaling pathway 0060395:SMAD protein signal transduction 0032991:protein-containing complex 0045669:positive regulation of osteoblast differentiation 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 0006468:protein phosphorylation 0071141:SMAD protein complex 0007165:signal transduction 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0005654:nucleoplasm 0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific 0046872:metal ion binding 1990837:sequence-specific double-stranded DNA binding 0007281:germ cell development
PDB	6TCE ; 6FZS
Drugbank	NA
KEGG	hsa:4090

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Name: Valproic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens