Target Description

Type Detail
Target ID T55LCD
Protein Name POU domain, class 5, transcription factor 1
Uniprot ID Q01860
Protein Name Alias Octamer-binding protein 3;  Oct-3;  Octamer-binding protein 4;  Oct-4;  Octamer-binding transcription factor 3;  OTF-3
Gene ID 5460
Gene Symbol POU5F1
Gene Alias OCT3;  OCT4;  OTF3
TTD NA
Pfam PF00157 ; PF00046
GO
0003677:DNA binding

0008134:transcription factor binding

0005634:nucleus

0060391:positive regulation of SMAD protein signal transduction

0043565:sequence-specific DNA binding

0005829:cytosol

0006355:regulation of transcription, DNA-templated

0031625:ubiquitin protein ligase binding

0010468:regulation of gene expression

0035019:somatic stem cell population maintenance

0009653:anatomical structure morphogenesis

0060913:cardiac cell fate determination

0060965:negative regulation of gene silencing by miRNA

0000976:transcription regulatory region sequence-specific DNA binding

0003723:RNA binding

1902894:negative regulation of pri-miRNA transcription by RNA polymerase II

0003130:BMP signaling pathway involved in heart induction

0005667:transcription regulator complex

0090081:regulation of heart induction by regulation of canonical Wnt signaling pathway

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0000122:negative regulation of transcription by RNA polymerase II

0003700:DNA-binding transcription factor activity

0005739:mitochondrion

0005737:cytoplasm

0009611:response to wounding

0009786:regulation of asymmetric cell division

0090308:regulation of DNA methylation-dependent heterochromatin assembly

0006357:regulation of transcription by RNA polymerase II

0060795:cell fate commitment involved in formation of primary germ layer

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

1990837:sequence-specific double-stranded DNA binding

0035198:miRNA binding

0001714:endodermal cell fate specification

0045944:positive regulation of transcription by RNA polymerase II

0090263:positive regulation of canonical Wnt signaling pathway

0001824:blastocyst development

PDB 6YOV ; 6T90
Drugbank DB00368 ; DB00988
KEGG hsa:5460

Related Compounds  (Total: 3)

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C0281
Name: Paclitaxel
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C0477
Name: Valproic Acid
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C0934
Name: Aspirin


Related Herbs  (Total: 11)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0463 Shi Liu Pi石榴皮 Pomegranate peelPunica granatum
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0462 Shi Liu石榴 Pomegranate fruitPunica granatum
H0464 Shi Liu Zi石榴子 NAPunica granatum
H0515 Suan Shi Liu酸石榴 PomegranatePunica granatum
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens