Compound Description

ID:   C0934 Common name:   Aspirin
IUPAC:  2-acetyloxybenzoic acid CAS:  CAS:50-78-2
Chembl ID:   CHEMBL25 Pubchem ID:   CID:2244
Formula:  C9H8O4 TCM-ID:  TCMC736
Smiles:  CC(=O)Oc1ccccc1C(=O)O
Alias:

Rhodine;

Salicylic acid acetate;

2-(Acetyloxy)benzoic acid;

2-Acetoxybenzoic acid;

2-Carboxyphenyl acetate;

A.S.A. Empirin;

AC 5230;

ASA;

Acenterine;

Acesal;

Acesan;

Acetard;

Aceticyl;

Acetilum acidulatum;

Acetisal;

Acetol;

Acetonyl;

Acetophen;

Acetosal;

Acetosalic acid;

Acetosalin;

Acetylin;

Acetylsal;

Acetylsalicylic acid;

Acetyonyl;

Acetysal;

Acidum acetylsalicylicum;

Acimetten;

Acisal;

Acylpyrin;

Adiro;

Albyl E;

Angettes 75;

Anopyrin;

Asaflow;

Asagran;

Asatard;

Ascoden 30;

Ascolong;

Ascriptin;

Aspalon;

Aspergum;

Aspirdrops;

Aspirin;

Aspirin Protect 100;

Aspirin Protect 300;

Aspirin-Direkt;

Aspirina;

Aspirina 03;

Aspirine;

Aspro;

Aspro Clear;

Aspropharm;

Asteric;

Astrix;

Bayaspirin;

Benaspir;

Bialpirina;

Bialpirinia;

Caprin;

Cardioaspirin;

Cardioaspirina;

Cardiomagnyl;

Claradin;

Colfarit;

Colsprin;

Contrheuma Retard;

Coraspin;

Coricidin;

Coricidin D;

Crystar;

Darvon Compound;

Dolean pH 8;

Dominal;

Duramax;

Durlaza;

ECM;

Easprin;

Ecopirin;

Ecosprin;

Ecotrin;

Empirin;

Endosprin;

Endydol;

Entericin;

Enterophen;

Enterosarine;

Entrophen;

Ewin;

Extren;

Gelprin;

Globentyl;

Globoid;

Helicon;

IWN 11;

Idragin;

Istopirin;

Kapsazal;

Lysoprin (pharmaceutical);

Magnecyl;

Measurin;

Medisyl;

Melhoral;

Micristin;

Miniasal;

Mycropyrin;

NSC 27223;

NSC 406186;

Neuronika;

Novid;

Nu-seals;

O-Acetylsalicylic acid;

Persistin;

Polopiryna;

Rheumintabletten;

Rhodine 2312;

Rhodine 3040;

Rhodine 3118;

Rhodine 3220;

Rhodine NC RP;

Rhonal;

Rivo;

Rodine 3220;

SP 189;

Salacetin;

Salcetogen;

Saletin;

Salospir;

Salycylacetylsalicylic acid;

Solpyron;

Supac;

Temperal;

ThromboASS;

Toldex;

Triple-sal;

Trombyl;

Xaxa;

Yasta;

Zorprin;

Zosprin;

o-(Acetyloxy)benzoic acid;

o-Acetoxybenzoic acid;

o-Carboxyphenyl acetate
Structure:

Related Targets  (Total: 63)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T06RMZ Nuclear factor NF-kappa-B p105 subunitNFKB1 P19838
A 4 Reference(s)
T83P5X Inhibitor of nuclear factor kappa-B kinase subunit betaIKBKB O14920
A 1 Reference(s)
T00CXT Prostaglandin G/H synthase 1PTGS1 P23219
A 14 Reference(s)
T08Q7W Prostaglandin G/H synthase 2PTGS2 P35354
A 12 Reference(s)
T06QUL FractalkineCX3CL1 P78423
A 2 Reference(s)
T74QXI Serine/threonine-protein kinase mTORMTOR P42345
A 1 Reference(s)
T78IOY Telomerase reverse transcriptaseTERT O14746
A 1 Reference(s)
T79KQO NF-kappa-B inhibitor alphaNFKBIA P25963
A 1 Reference(s)
T49TDM Matrix metalloproteinase-9MMP9 P14780
A 2 Reference(s)
T75B9S Cyclic AMP-responsive element-binding protein 1CREB1 P16220
A 1 Reference(s)
T42PUG Solute carrier family 2, facilitated glucose transporter member 1SLC2A1 P11166
A 1 Reference(s)
T97TGY Cytochrome c oxidase subunit 8A, mitochondrialCOX8A P10176
A 1 Reference(s)
T98RXH Focal adhesion kinase 1PTK2 Q05397
A 1 Reference(s)
T04WT7 FibronectinFN1 P02751
A 2 Reference(s)
T08TXH CX3C chemokine receptor 1CX3CR1 P49238
A 1 Reference(s)
T81I4T 5'-AMP-activated protein kinase catalytic subunit alpha-1PRKAA1 Q13131
A 4 Reference(s)
T55LCD POU domain, class 5, transcription factor 1POU5F1 Q01860
A 1 Reference(s)
T36SOV Plasminogen activator inhibitor 1SERPINE1 P05121
A 1 Reference(s)
T40Q1D Retinal dehydrogenase 1ALDH1A1 P00352
A 1 Reference(s)
T37VPC Homeobox protein NANOGNANOG Q9H9S0
A 1 Reference(s)
T82F70 Urokinase plasminogen activator surface receptorPLAUR Q03405
A 1 Reference(s)
T30VNV MyeloperoxidaseMPO P05164
B 1 Reference(s)
T49ORJ Peroxisome proliferator-activated receptor alphaPPARA Q07869
B 2 Reference(s)
T83A8U Prolyl 4-hydroxylase subunit alpha-2P4HA2 O15460
B 1 Reference(s)
T92BZ2 Catenin beta-1CTNNB1 P35222
B 2 Reference(s)
T28C2Z DystroglycanDAG1 Q14118
B 1 Reference(s)
T22NX4 Toll-like receptor 2TLR2 O60603
B 1 Reference(s)
T57ZFD Hepatic leukemia factorHLF Q16534
B 1 Reference(s)
T42EAZ Vascular endothelial growth factor AVEGFA P15692
B 1 Reference(s)
T91AZ4 S-adenosylmethionine synthase isoform type-1MAT1A Q00266
B 1 Reference(s)
T85HMF Metalloproteinase inhibitor 3TIMP3 P35625
B 1 Reference(s)
T88QQE Fibroblast growth factor 2FGF2 P09038
B 1 Reference(s)
T99ARN Forkhead box protein P3FOXP3 Q9BZS1
C 1 Reference(s)
T73V21 Transcription factor SOX-2SOX2 P48431
C 1 Reference(s)
T88HDQ Tyrosine-protein phosphatase non-receptor type 13PTPN13 Q12923
C 1 Reference(s)
T32IXS Integrin alpha-MITGAM P11215
C 1 Reference(s)
T54CIF Interleukin-8CXCL8 P10145
C 1 Reference(s)
T93SFQ NAD-dependent protein deacetylase sirtuin-1SIRT1 Q96EB6
C 1 Reference(s)
T50V79 Interleukin-4IL4 P05112
C 2 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
C 1 Reference(s)
T38WWN Serum paraoxonase/arylesterase 1PON1 P27169
C 1 Reference(s)
T46BOC 60 kDa heat shock protein, mitochondrialHSPD1 P10809
C 1 Reference(s)
T85U8U Caspase-3CASP3 P42574
C 1 Reference(s)
T61YYB ATP-binding cassette sub-family C member 4ABCC4 O15439
C 3 Reference(s)
T12SQ3 Interleukin-11IL11 P20809
C 1 Reference(s)
T99XJ1 Serpin H1SERPINH1 P50454
C 1 Reference(s)
T58K75 Transcription factor AP-2-alphaTFAP2A P05549
C 1 Reference(s)
T46K2X Heat shock 70 kDa protein 4HSPA4 P34932
C 1 Reference(s)
T67NVI DNA repair protein XRCC3XRCC3 O43542
C 1 Reference(s)
T14Q85 HeparanaseHPSE Q9Y251
C 1 Reference(s)
T77FOL NeuromodulinGAP43 P17677
C 1 Reference(s)
T26EZU Myc proto-oncogene proteinMYC P01106
C 1 Reference(s)
T86N8L SecurinPTTG1 O95997
C 1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
C 1 Reference(s)
T75SPS Fibroblast growth factor 1FGF1 P05230
C 1 Reference(s)
T95IYZ AdiponectinADIPOQ Q15848
C 1 Reference(s)
T71K92 Apoptosis regulator Bcl-2BCL2 P10415
C 1 Reference(s)
T29MD1 Mitogen-activated protein kinase 8MAPK8 P45983
C 1 Reference(s)
T57R3V Proliferation marker protein Ki-67MKI67 P46013
C 1 Reference(s)
T91SMW 5'-AMP-activated protein kinase subunit gamma-2PRKAG2 Q9UGJ0
C 1 Reference(s)
T11BI7 Toll-like receptor 4TLR4 O00206
C 1 Reference(s)
T20FRX Protein S100-A8S100A8 P05109
C 1 Reference(s)
T53AOE Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptideTGFB1 P01137
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin