HIT-result

Target Description

Type	Detail
Target ID	T40Q1D
Protein Name	Retinal dehydrogenase 1
Uniprot ID	P00352
Protein Name Alias	RALDH 1; RalDH1; EC 1.2.1.-; EC 1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic
Gene ID	216
Gene Symbol	ALDH1A1
Gene Alias	ALDC; ALDH1; PUMB1
TTD	T99641: Successful target
Pfam	PF00171
GO	0005737:cytoplasm 0018479:benzaldehyde dehydrogenase (NAD+) activity 0004029:aldehyde dehydrogenase (NAD+) activity 0070062:extracellular exosome 0001758:retinal dehydrogenase activity 0051287:NAD binding 0006081:cellular aldehyde metabolic process 0042572:retinol metabolic process 0001523:retinoid metabolic process 0005829:cytosol 0005096:GTPase activator activity 0005497:androgen binding 0006069:ethanol oxidation 0061624:fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate 0120163:negative regulation of cold-induced thermogenesis
PDB	5L2N ; 4X4L ; 4WJ9 ; 4WP7 ; 6DUM ; 4WB9 ; 5TEI ; 5L2M ; 5L2O ; 4WPN ; 5AC2
Drugbank	DB09462 ; DB04447 ; DB00162 ; DB00157 ; DB00755
KEGG	hsa:216

Type

Detail

Target ID

T40Q1D

Protein Name

Retinal dehydrogenase 1

Uniprot ID

P00352

Protein Name Alias

RALDH 1; RalDH1; EC 1.2.1.-; EC 1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic

Gene ID

216

Gene Symbol

ALDH1A1

Gene Alias

ALDC; ALDH1; PUMB1

TTD

T99641: Successful target

Pfam

PF00171

0005737:cytoplasm

0018479:benzaldehyde dehydrogenase (NAD+) activity

0004029:aldehyde dehydrogenase (NAD+) activity

0070062:extracellular exosome

0001758:retinal dehydrogenase activity

0051287:NAD binding

0006081:cellular aldehyde metabolic process

0042572:retinol metabolic process

0001523:retinoid metabolic process

0005829:cytosol

0005096:GTPase activator activity

0005497:androgen binding

0006069:ethanol oxidation

0061624:fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

0120163:negative regulation of cold-induced thermogenesis

PDB

5L2N ; 4X4L ; 4WJ9 ; 4WP7 ; 6DUM ; 4WB9 ; 5TEI ; 5L2M ; 5L2O ; 4WPN ; 5AC2

Drugbank

DB09462 ; DB04447 ; DB00162 ; DB00157 ; DB00755

KEGG

hsa:216

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Name: Dopa

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Name: Sulforaphane

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Name: Tretinoin

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Name: Aspirin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0125	Lai Fu	莱菔	Garden radish	Raphanus sativus
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0126	Lai Fu Zi	莱菔子	Garden radish seed	Raphanus sativus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0466	Cai Fu Zi	菜菔子	Semen raphani	Raphanus sativus
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin

Target Description

Related Compounds (Total: 4)

Related Herbs (Total: 13)