HIT-result

Type	Detail
Target ID	T08TXH
Protein Name	CX3C chemokine receptor 1
Uniprot ID	P49238
Protein Name Alias	C-X3-C CKR-1; CX3CR1; Beta chemokine receptor-like 1; CMK-BRL-1; CMK-BRL1; Fractalkine receptor; G-protein coupled receptor 13; V28
Gene ID	1524
Gene Symbol	CX3CR1
Gene Alias	CMKBRL1; GPR13
TTD	T15033: Research target
Pfam	PF00001
GO	0016495:C-X3-C chemokine receptor activity 0051092:positive regulation of NF-kappaB transcription factor activity 0045087:innate immune response 0110091:negative regulation of hippocampal neuron apoptotic process 0050767:regulation of neurogenesis 0035176:social behavior 0098883:synapse pruning 0007186:G protein-coupled receptor signaling pathway 0009986:cell surface 0048471:perinuclear region of cytoplasm 0009897:external side of plasma membrane 0032691:negative regulation of interleukin-1 beta production 0060074:synapse maturation 0007155:cell adhesion 2001234:negative regulation of apoptotic signaling pathway 0071222:cellular response to lipopolysaccharide 0045766:positive regulation of angiogenesis 0002931:response to ischemia 1900272:negative regulation of long-term synaptic potentiation 0002052:positive regulation of neuroblast proliferation 0007613:memory 0005887:integral component of plasma membrane 1904139:regulation of microglial cell migration 0006935:chemotaxis 0045428:regulation of nitric oxide biosynthetic process 0050901:leukocyte tethering or rolling 0016032:viral process 0021626:central nervous system maturation 0009611:response to wounding 0032809:neuronal cell body membrane 0043005:neuron projection 0019960:C-X3-C chemokine binding 0150090:multiple spine synapse organization, single dendrite 0060326:cell chemotaxis 0019722:calcium-mediated signaling 0004930:G protein-coupled receptor activity 0005886:plasma membrane 0030336:negative regulation of cell migration 0048167:regulation of synaptic plasticity 0016493:C-C chemokine receptor activity 0006968:cellular defense response 0032680:regulation of tumor necrosis factor production 0007200:phospholipase C-activating G protein-coupled receptor signaling pathway 1904141:positive regulation of microglial cell migration 0051897:positive regulation of protein kinase B signaling 0050804:modulation of chemical synaptic transmission 0004950:chemokine receptor activity 0097447:dendritic tree 0050769:positive regulation of neurogenesis 0035425:autocrine signaling 0006955:immune response 0007204:positive regulation of cytosolic calcium ion concentration 1903721:positive regulation of I-kappaB phosphorylation 0007267:cell-cell signaling 0019957:C-C chemokine binding 0008528:G protein-coupled peptide receptor activity 0071560:cellular response to transforming growth factor beta stimulus
PDB	NA
Drugbank	NA
KEGG	hsa:1524

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Name: Aspirin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin