Target Description

Type Detail
Target ID T73V21
Protein Name Transcription factor SOX-2
Uniprot ID P48431
Protein Name Alias NA
Gene ID 6657
Gene Symbol SOX2
Gene Alias NA
TTD T00724: Research target
Pfam PF12336 ; PF00505
GO
0003677:DNA binding

0005634:nucleus

0043410:positive regulation of MAPK cascade

0021984:adenohypophysis development

0007050:cell cycle arrest

0043565:sequence-specific DNA binding

0005829:cytosol

0006355:regulation of transcription, DNA-templated

0010468:regulation of gene expression

0035019:somatic stem cell population maintenance

0009653:anatomical structure morphogenesis

0005737:cytoplasm

0030154:cell differentiation

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0045165:cell fate commitment

0050680:negative regulation of epithelial cell proliferation

0000785:chromatin

0042246:tissue regeneration

0000976:transcription regulatory region sequence-specific DNA binding

0097150:neuronal stem cell population maintenance

0070848:response to growth factor

0001654:eye development

0045665:negative regulation of neuron differentiation

0001649:osteoblast differentiation

0030900:forebrain development

0005667:transcription regulator complex

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045893:positive regulation of transcription, DNA-templated

0000122:negative regulation of transcription by RNA polymerase II

0021983:pituitary gland development

0003700:DNA-binding transcription factor activity

0009611:response to wounding

0045597:positive regulation of cell differentiation

0090090:negative regulation of canonical Wnt signaling pathway

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0021781:glial cell fate commitment

0048839:inner ear development

0035198:miRNA binding

0019221:cytokine-mediated signaling pathway

0043281:regulation of cysteine-type endopeptidase activity involved in apoptotic process

0001714:endodermal cell fate specification

0022409:positive regulation of cell-cell adhesion

0045944:positive regulation of transcription by RNA polymerase II

0006325:chromatin organization

PDB 1O4X ; 6YOV ; 6T7B ; 6WX9 ; 6T90 ; 6WX8 ; 2LE4 ; 6WX7
Drugbank NA
KEGG hsa:6657

Related Compounds  (Total: 4)

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C0456
Name: Tretinoin
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C0930
Name: Astragaloside Iv
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C0934
Name: Aspirin
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C1184
Name: Bile Acid


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0431 She Dan Zhi蛇胆汁 Snake bileFel serpentis liquidum
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1247 Huang Qi黄芪 Membranous milkvetchAstragalus membranaceus
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens