HIT-result

Type	Detail
Target ID	T46BOC
Protein Name	60 kDa heat shock protein, mitochondrial
Uniprot ID	P10809
Protein Name Alias	EC 5.6.1.7; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein
Gene ID	3329
Gene Symbol	HSPD1
Gene Alias	HSP60
TTD	T11283: Clinical Trial target
Pfam	PF00118
GO	0070062:extracellular exosome 0002755:MyD88-dependent toll-like receptor signaling pathway 0030135:coated vesicle 0032991:protein-containing complex 0034514:mitochondrial unfolded protein response 0005615:extracellular space 0006457:protein folding 0005524:ATP binding 0034186:apolipoprotein A-I binding 0051087:chaperone binding 0031625:ubiquitin protein ligase binding 0051702:biological process involved in interaction with symbiont 0032755:positive regulation of interleukin-6 production 0003688:DNA replication origin binding 0043066:negative regulation of apoptotic process 0002842:positive regulation of T cell mediated immune response to tumor cell 0008637:apoptotic mitochondrial changes 0016020:membrane 0016853:isomerase activity 0005743:mitochondrial inner membrane 0009986:cell surface 0005829:cytosol 0032733:positive regulation of interleukin-10 production 0043065:positive regulation of apoptotic process 0032729:positive regulation of interferon-gamma production 0046696:lipopolysaccharide receptor complex 0050821:protein stabilization 0034185:apolipoprotein binding 0006458:'de novo' protein folding 0042110:T cell activation 0005886:plasma membrane 0030141:secretory granule 0001530:lipopolysaccharide binding 0042100:B cell proliferation 0003697:single-stranded DNA binding 0045041:protein import into mitochondrial intermembrane space 0003725:double-stranded RNA binding 0019899:enzyme binding 0008035:high-density lipoprotein particle binding 0005737:cytoplasm 0002039:p53 binding 0006919:activation of cysteine-type endopeptidase activity involved in apoptotic process 0016887:ATPase activity 0003723:RNA binding 0005739:mitochondrion 0032727:positive regulation of interferon-alpha production 0051604:protein maturation 0009409:response to cold 0048291:isotype switching to IgG isotypes 0051082:unfolded protein binding 0051131:chaperone-mediated protein complex assembly 0042026:protein refolding 0005759:mitochondrial matrix 0005905:clathrin-coated pit 0050870:positive regulation of T cell activation 0005769:early endosome 0043032:positive regulation of macrophage activation 0042113:B cell activation 0016032:viral process 0006986:response to unfolded protein 0032735:positive regulation of interleukin-12 production 0006357:regulation of transcription by RNA polymerase II
PDB	6MRD ; 4PJ1 ; 6MRC ; 6HT7
Drugbank	DB09130
KEGG	hsa:3329

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Name: Aspirin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin