Target Description

Type Detail
Target ID T58K75
Protein Name Transcription factor AP-2-alpha
Uniprot ID P05549
Protein Name Alias AP2-alpha;  AP-2 transcription factor;  Activating enhancer-binding protein 2-alpha;  Activator protein 2;  AP-2
Gene ID 7020
Gene Symbol TFAP2A
Gene Alias AP2TF;  TFAP2
TTD T71317: Research target
Pfam PF03299
GO
0003677:DNA binding

0042802:identical protein binding

0005634:nucleus

0061029:eyelid development in camera-type eye

0070172:positive regulation of tooth mineralization

2000378:negative regulation of reactive oxygen species metabolic process

0043565:sequence-specific DNA binding

0003404:optic vesicle morphogenesis

0060349:bone morphogenesis

0048701:embryonic cranial skeleton morphogenesis

0042472:inner ear morphogenesis

0042127:regulation of cell population proliferation

0048856:anatomical structure development

0003682:chromatin binding

0010842:retina layer formation

0043525:positive regulation of neuron apoptotic process

0008285:negative regulation of cell population proliferation

0045892:negative regulation of transcription, DNA-templated

0021623:oculomotor nerve formation

0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding

0060021:roof of mouth development

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

0010628:positive regulation of gene expression

0007605:sensory perception of sound

0030501:positive regulation of bone mineralization

0000785:chromatin

0001822:kidney development

0000976:transcription regulatory region sequence-specific DNA binding

0003409:optic cup structural organization

0035115:embryonic forelimb morphogenesis

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0045893:positive regulation of transcription, DNA-templated

0021559:trigeminal nerve development

0140536:nuclear receptor corepressor activity

0071281:cellular response to iron ion

0000122:negative regulation of transcription by RNA polymerase II

0006357:regulation of transcription by RNA polymerase II

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0005654:nucleoplasm

0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific

1990837:sequence-specific double-stranded DNA binding

0010944:negative regulation of transcription by competitive promoter binding

0045595:regulation of cell differentiation

0045944:positive regulation of transcription by RNA polymerase II

0043066:negative regulation of apoptotic process

PDB NA
Drugbank NA
KEGG hsa:7020

Related Compounds  (Total: 1)

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C0934
Name: Aspirin


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin