Target Description

Type Detail
Target ID T61YYB
Protein Name ATP-binding cassette sub-family C member 4
Uniprot ID O15439
Protein Name Alias EC 7.6.2.-;  EC 7.6.2.2;  EC 7.6.2.3;  MRP/cMOAT-related ABC transporter;  Multi-specific organic anion transporter B;  MOAT-B;  Multidrug resistance-associated protein 4
Gene ID 10257
Gene Symbol ABCC4
Gene Alias MOATB;  MRP4
TTD T39919: Research target
Pfam PF00664 ; PF00005
GO
0015132:prostaglandin transmembrane transporter activity

0098591:external side of apical plasma membrane

0015721:bile acid and bile salt transport

0016021:integral component of membrane

0005524:ATP binding

0016404:15-hydroxyprostaglandin dehydrogenase (NAD+) activity

0042493:response to drug

0001409:guanine nucleotide transmembrane transporter activity

0150104:transport across blood-brain barrier

0016020:membrane

0015143:urate transmembrane transporter activity

0015431:ABC-type glutathione S-conjugate transporter activity

0015732:prostaglandin transport

0140115:export across plasma membrane

0002576:platelet degranulation

0055085:transmembrane transport

0015747:urate transport

0034634:glutathione transmembrane transporter activity

0060271:cilium assembly

0010243:response to organonitrogen compound

0031088:platelet dense granule membrane

0015562:efflux transmembrane transporter activity

0005886:plasma membrane

0048661:positive regulation of smooth muscle cell proliferation

0070730:cAMP transport

0014070:response to organic cyclic compound

0042910:xenobiotic transmembrane transporter activity

0016887:ATPase activity

0042626:ATPase-coupled transmembrane transporter activity

0016323:basolateral plasma membrane

0038183:bile acid signaling pathway

0071716:leukotriene transport

0015216:purine nucleotide transmembrane transporter activity

0015432:ABC-type bile acid transporter activity

0032310:prostaglandin secretion

0016324:apical plasma membrane

PDB NA
Drugbank DB08884 ; DB01327 ; DB00586 ; DB01268 ; DB14126 ; DB01009 ; DB00352 ; DB00300 ; DB00482 ; DB01033 ; DB09213 ; DB01138 ; DB00770 ; DB00563 ; DB00718 ; DB00712 ; DB00709 ; DB01069 ; DB04348 ; DB01050 ; DB00495 ; DB01708 ; DB00975 ; DB00286 ; DB00814 ; DB00143 ; DB00203 ; DB00328 ; DB01032 ; DB00171 ; DB02527 ; DB00544 ; DB00999 ; DB00533 ; DB00661 ; DB00398 ; DB12332 ; DB13146 ; DB01586 ; DB02659 ; DB00158 ; DB00481 ; DB01098 ; DB00731 ; DB00917 ; DB14761 ; DB01076 ; DB09299 ; DB00198
KEGG hsa:10257

Related Compounds  (Total: 2)

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C0876
Name: Allopurinol
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C0934
Name: Aspirin


Related Herbs  (Total: 7)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens