HIT-result

Type	Detail
Target ID	T82F70
Protein Name	Urokinase plasminogen activator surface receptor
Uniprot ID	Q03405
Protein Name Alias	U-PAR; uPAR; Monocyte activation antigen Mo3; CD antigen CD87
Gene ID	5329
Gene Symbol	PLAUR
Gene Alias	MO3; UPAR
TTD	T74363: Successful target
Pfam	PF00021
GO	0007596:blood coagulation 2001243:negative regulation of intrinsic apoptotic signaling pathway 0001934:positive regulation of protein phosphorylation 0042995:cell projection 0090200:positive regulation of release of cytochrome c from mitochondria 0035579:specific granule membrane 0045742:positive regulation of epidermal growth factor receptor signaling pathway 0030162:regulation of proteolysis 0043066:negative regulation of apoptotic process 0019899:enzyme binding 2001268:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0030377:urokinase plasminogen activator receptor activity 0005789:endoplasmic reticulum membrane 0007165:signal transduction 0009986:cell surface 0042730:fibrinolysis 0019898:extrinsic component of membrane 0016021:integral component of membrane 0043312:neutrophil degranulation 0005925:focal adhesion 0031225:anchored component of membrane 0005576:extracellular region 0034112:positive regulation of homotypic cell-cell adhesion 0005102:signaling receptor binding 0043388:positive regulation of DNA binding 0005886:plasma membrane 0038023:signaling receptor activity 0019904:protein domain specific binding 0005887:integral component of plasma membrane 0006935:chemotaxis 0005788:endoplasmic reticulum lumen
PDB	4K24 ; 1YWH ; 2FD6 ; 3U74 ; 3U73 ; 2I9B ; 3BT1 ; 4QTI ; 3BT2
Drugbank	DB00009 ; DB06245 ; DB05476 ; DB00013 ; DB00031
KEGG	hsa:5329

Go to browser

Name: Simvastatin

Go to browser

Name: Aspirin

Go to browser

Name: Atorvastatin

Go to browser

Name: Colchicine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0560	Cao Bei Mu	草贝母	Indian iphigenia	Iphigenia indica
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0132	Li Lu	藜芦	Black falsehellebore	Veratrum nigrum
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin