Target Description

Type Detail
Target ID T82F70
Protein Name Urokinase plasminogen activator surface receptor
Uniprot ID Q03405
Protein Name Alias U-PAR;  uPAR;  Monocyte activation antigen Mo3;  CD antigen CD87
Gene ID 5329
Gene Symbol PLAUR
Gene Alias MO3;  UPAR
TTD T74363: Successful target
Pfam PF00021
GO
0007596:blood coagulation

2001243:negative regulation of intrinsic apoptotic signaling pathway

0001934:positive regulation of protein phosphorylation

0042995:cell projection

0090200:positive regulation of release of cytochrome c from mitochondria

0035579:specific granule membrane

0045742:positive regulation of epidermal growth factor receptor signaling pathway

0030162:regulation of proteolysis

0043066:negative regulation of apoptotic process

0019899:enzyme binding

2001268:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

0030377:urokinase plasminogen activator receptor activity

0005789:endoplasmic reticulum membrane

0007165:signal transduction

0009986:cell surface

0042730:fibrinolysis

0019898:extrinsic component of membrane

0016021:integral component of membrane

0043312:neutrophil degranulation

0005925:focal adhesion

0031225:anchored component of membrane

0005576:extracellular region

0034112:positive regulation of homotypic cell-cell adhesion

0005102:signaling receptor binding

0043388:positive regulation of DNA binding

0005886:plasma membrane

0038023:signaling receptor activity

0019904:protein domain specific binding

0005887:integral component of plasma membrane

0006935:chemotaxis

0005788:endoplasmic reticulum lumen

PDB 4K24 ; 1YWH ; 2FD6 ; 3U74 ; 3U73 ; 2I9B ; 3BT1 ; 4QTI ; 3BT2
Drugbank DB00009 ; DB06245 ; DB05476 ; DB00013 ; DB00031
KEGG hsa:5329

Related Compounds  (Total: 4)

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C0406
Name: Simvastatin
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C0934
Name: Aspirin
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C0987
Name: Atorvastatin
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C1250
Name: Colchicine


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0560 Cao Bei Mu草贝母 Indian iphigeniaIphigenia indica
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0132 Li Lu藜芦 Black falsehelleboreVeratrum nigrum