HIT-result

Type	Detail
Target ID	T14Q85
Protein Name	Heparanase
Uniprot ID	Q9Y251
Protein Name Alias	EC 3.2.1.166; Endo-glucoronidase; Heparanase-1; Hpa1
Gene ID	10855
Gene Symbol	HPSE
Gene Alias	HEP; HPA; HPA1; HPR1; HPSE1; HSE1
TTD	T47623: Successful target
Pfam	PF03662
GO	0005634:nucleus 0030200:heparan sulfate proteoglycan catabolic process 0005765:lysosomal membrane 0061042:vascular wound healing 0031012:extracellular matrix 0045545:syndecan binding 0043231:intracellular membrane-bounded organelle 0051798:positive regulation of hair follicle development 0060055:angiogenesis involved in wound healing 0005654:nucleoplasm 1904974:heparanase complex 0004566:beta-glucuronidase activity 0006027:glycosaminoglycan catabolic process 0007160:cell-matrix adhesion 0005764:lysosome 0043202:lysosomal lumen 0045121:membrane raft 0030194:positive regulation of blood coagulation 0043312:neutrophil degranulation 0005576:extracellular region 0030305:heparanase activity 0035580:specific granule lumen 0051897:positive regulation of protein kinase B signaling 0033690:positive regulation of osteoblast proliferation 0051797:regulation of hair follicle development 0006029:proteoglycan metabolic process 0010575:positive regulation of vascular endothelial growth factor production
PDB	5LA7 ; 5L9Y ; 5LA4 ; 5E98 ; 5E8M ; 5L9Z ; 5E9B ; 5E97 ; 5E9C ; 6ZDM
Drugbank	DB06779 ; DB01109
KEGG	hsa:10855

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Name: Ethinyl Estradiol

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Name: Aspirin

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Name: enoxaparin

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Name: matrine

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Name: heparin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin