Herb Description
| Herb ID: H0159 | Chinese Character: 半夏曲 |
| English Name: Pinellia tuber leaven | Latin Name: Pinellia ternata |
| Chinese Pin Yin : Ban Xia Qu | TCM-ID: TCMH131 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 145)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T00T99 | S-adenosylhomocysteine hydrolase-like protein 1 | AHCYL1 |
O43865 |
1 Reference(s) |
| T21CMG | Hepcidin | HAMP |
P81172 |
2 Reference(s) |
| T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
| T31ZFD | Aldehyde oxidase | AOX1 |
Q06278 |
1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
28 Reference(s) |
| T86MX7 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | CD38 |
P28907 |
2 Reference(s) |
| T41BXR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | SIRT3 |
Q9NTG7 |
3 Reference(s) |
| T40DE5 | Tryptophan 2,3-dioxygenase | TDO2 |
P48775 |
1 Reference(s) |
| T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
3 Reference(s) |
| T21PEZ | NAD(+) hydrolase SARM1 | SARM1 |
Q6SZW1 |
1 Reference(s) |
| T22NX4 | Toll-like receptor 2 | TLR2 |
O60603 |
1 Reference(s) |
| T76QBQ | CREB-regulated transcription coactivator 2 | CRTC2 |
Q53ET0 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
3 Reference(s) |
| T25M2J | Anoctamin-1 | ANO1 |
Q5XXA6 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
4 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
6 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
| T62FNY | Adenosine receptor A3 | ADORA3 |
P0DMS8 |
1 Reference(s) |
| T47DYR | P2Y purinoceptor 1 | P2RY1 |
P47900 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
2 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
2 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
3 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
5 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
3 Reference(s) |
| T38N69 | Lymphokine-activated killer T-cell-originated protein kinase | PBK |
Q96KB5 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
2 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
6 Reference(s) |
| T74LFK | Neurogenic locus notch homolog protein 1 | NOTCH1 |
P46531 |
1 Reference(s) |
| T60XJI | Transient receptor potential cation channel subfamily M member 8 | TRPM8 |
Q7Z2W7 |
1 Reference(s) |
| T09INZ | Transient receptor potential cation channel subfamily A member 1 | TRPA1 |
O75762 |
2 Reference(s) |
| T12BGL | Cytochrome P450 2A6 | CYP2A6 |
P11509 |
1 Reference(s) |
| T46AXP | Cytochrome P450 2A13 | CYP2A13 |
Q16696 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
4 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
7 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T14BVD | Protein arginine N-methyltransferase 5 | PRMT5 |
O14744 |
1 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
2 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
4 Reference(s) |
| T37G49 | Platelet-activating factor acetylhydrolase | PLA2G7 |
Q13093 |
1 Reference(s) |
| T72U9G | Tumor necrosis factor receptor superfamily member 9 | TNFRSF9 |
Q07011 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
2 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
5 Reference(s) |
| T53YWQ | Pro-neuropeptide Y [Cleaved into: Neuropeptide Y | NPY |
P01303 |
2 Reference(s) |
| T75HMM | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 |
Q07820 |
1 Reference(s) |
| T00RU5 | Histone H1.0 | H1-0 |
P07305 |
1 Reference(s) |
| T37V37 | Prostaglandin-H2 D-isomerase | PTGDS |
P41222 |
1 Reference(s) |
| T09DI4 | Lysine-specific histone demethylase 1A | KDM1A |
O60341 |
1 Reference(s) |
| T78VUO | RAF proto-oncogene serine/threonine-protein kinase | RAF1 |
P04049 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
3 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
2 Reference(s) |
| T69XVX | Cytochrome P450 1B1 | CYP1B1 |
Q16678 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
1 Reference(s) |
| T05V67 | Toll-like receptor 8 | TLR8 |
Q9NR97 |
1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
3 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
2 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
6 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
3 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
3 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
1 Reference(s) |
| T66G0O | NA | MIR30A |
NA |
1 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
1 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
1 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
1 Reference(s) |
| T63FF5 | Interferon regulatory factor 3 | IRF3 |
Q14653 |
2 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
2 Reference(s) |
| T76TED | Pro-opiomelanocortin | POMC |
P01189 |
1 Reference(s) |
| T37JN5 | Neutrophil gelatinase-associated lipocalin | LCN2 |
P80188 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
2 Reference(s) |
| T64V6C | Glutamate decarboxylase 1 | GAD1 |
Q99259 |
1 Reference(s) |
| T83RKS | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | MGAT1 |
P26572 |
2 Reference(s) |
| T73PZA | Vesicular inhibitory amino acid transporter | SLC32A1 |
Q9H598 |
1 Reference(s) |
| T68XXK | 4-aminobutyrate aminotransferase, mitochondrial | ABAT |
P80404 |
4 Reference(s) |
| T35WLZ | Sodium- and chloride-dependent GABA transporter 3 | SLC6A11 |
P48066 |
2 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
1 Reference(s) |
| T41Z1X | Gamma-aminobutyric acid receptor-associated protein | GABARAP |
O95166 |
1 Reference(s) |
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM |
O43451 |
1 Reference(s) |
| T77M4W | Adenosine receptor A2a | ADORA2A |
P29274 |
1 Reference(s) |
| T72J3R | Secretogranin-1 | CHGB |
P05060 |
1 Reference(s) |
| T02WMA | Ornithine decarboxylase | ODC1 |
P11926 |
1 Reference(s) |
| T41BYM | Fibroblast growth factor 23 | FGF23 |
Q9GZV9 |
1 Reference(s) |
| T85CC2 | Peptidyl-prolyl cis-trans isomerase D | PPID |
Q08752 |
1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T16O4B | CCAAT/enhancer-binding protein epsilon | CEBPE |
Q15744 |
1 Reference(s) |
| T10WEJ | Betaine--homocysteine S-methyltransferase 1 | BHMT |
Q93088 |
1 Reference(s) |
| T99HGY | Ubiquitin-protein ligase E3A | UBE3A |
Q05086 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T51EKP | Apolipoprotein M | APOM |
O95445 |
1 Reference(s) |
| T07VV7 | Guanylin | GUCA2A |
Q02747 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
2 Reference(s) |
| T80WPU | Protein ABHD15 | ABHD15 |
Q6UXT9 |
1 Reference(s) |
| T56OUM | 14-3-3 protein zeta/delta | YWHAZ |
P63104 |
1 Reference(s) |
| T24YWQ | Insulin-degrading enzyme | IDE |
P14735 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T39M6J | ATP-binding cassette sub-family C member 2 | ABCC2 |
Q92887 |
1 Reference(s) |
| T33KFW | Matrilysin | MMP7 |
P09237 |
1 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
1 Reference(s) |
| T42D4V | Histone deacetylase 1 | HDAC1 |
Q13547 |
1 Reference(s) |
| T54B00 | P2X purinoceptor 7 | P2RX7 |
Q99572 |
1 Reference(s) |
| T21UJU | Troponin I, cardiac muscle | TNNI3 |
P19429 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T60UPF | Parvalbumin alpha | PVALB |
P20472 |
2 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
1 Reference(s) |
| T18CUI | Neuron-specific calcium-binding protein hippocalcin | HPCA |
P84074 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T66S13 | Dual specificity mitogen-activated protein kinase kinase 2 | MAP2K2 |
P36507 |
1 Reference(s) |
| T08SJX | Astrocytic phosphoprotein PEA-15 | PEA15 |
Q15121 |
1 Reference(s) |
| T38OQ4 | Peroxiredoxin-2 | PRDX2 |
P32119 |
1 Reference(s) |
| T38J3Y | Gamma-enolase | ENO2 |
P09104 |
1 Reference(s) |
| T77W6N | Thioredoxin reductase 1, cytoplasmic | TXNRD1 |
Q16881 |
1 Reference(s) |
| T10I26 | Interferon beta | IFNB1 |
P01574 |
1 Reference(s) |
| T40EUL | Transient receptor potential cation channel subfamily V member 4 | TRPV4 |
Q9HBA0 |
1 Reference(s) |
| T98DNG | Natriuretic peptides A | NPPA |
P01160 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T68IZC | Natriuretic peptides B | NPPB |
P16860 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
1 Reference(s) |
| T02H9U | Nuclear factor of activated T-cells, cytoplasmic 4 | NFATC4 |
Q14934 |
1 Reference(s) |
| T82D6U | Ubiquitin-like protein ATG12 | ATG12 |
O94817 |
1 Reference(s) |
| T24V8E | Ubiquitin-like modifier-activating enzyme ATG7 | ATG7 |
O95352 |
1 Reference(s) |
| T24RSX | Autophagy protein 5 | ATG5 |
Q9H1Y0 |
1 Reference(s) |
| T95EK6 | Microtubule-associated proteins 1A/1B light chain 3B | MAP1LC3B |
Q9GZQ8 |
1 Reference(s) |
| T43NBB | Solute carrier family 2, facilitated glucose transporter member 2 | SLC2A2 |
P11168 |
1 Reference(s) |
| T51WGR | Pancreas/duodenum homeobox protein 1 | PDX1 |
P52945 |
1 Reference(s) |
| T82S6C | Hexokinase-4 | GCK |
P35557 |
1 Reference(s) |
| T18CPB | Choline O-acetyltransferase | CHAT |
P28329 |
1 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
1 Reference(s) |
| T03YAI | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 |
Q99683 |
1 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
1 Reference(s) |
| T48TW0 | Platelet glycoprotein 4 | CD36 |
P16671 |
1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
1 Reference(s) |
| T41TXS | Retinoblastoma-associated protein | RB1 |
P06400 |
1 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
1 Reference(s) |
| T02IOG | Cyclin-dependent kinase inhibitor 1B | CDKN1B |
P46527 |
1 Reference(s) |
Related Compounds (Total: 32)
C0863
Name: Adenine
C1162
Name: Benzaldehyde
C0246
Name: Niacinamide
C0285
Name: Palmitic Acid
C0064
Name: Eugenol
key description of the interaction between compound and target