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Target Description

Type Detail
Target ID T77W6N
Protein Name Thioredoxin reductase 1, cytoplasmic
Uniprot ID Q16881
Protein Name Alias TR;  EC 1.8.1.9;  Gene associated with retinoic and interferon-induced mortality 12 protein;  GRIM-12;  Gene associated with retinoic and IFN-induced mortality 12 protein;  KM-102-derived reductase-like factor;  Thioredoxin reductase TR1
Gene ID 7296
Gene Symbol TXNRD1
Gene Alias GRIM12;  KDRF
TTD T84581: Successful target
Pfam PF02852 ; PF00462 ; PF07992
GO
PDB 2CFY ; 2ZZ0 ; 1W1C ; 2ZZB ; 3QFA ; 2J3N ; 2ZZC ; 3QFB
Drugbank DB00126 ; DB02338 ; DB05448 ; DB03566 ; DB05428 ; DB04106 ; DB11135 ; DB11127 ; DB03147 ; DB01169
KEGG hsa:7296

Related Compounds  (Total: 8)

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C0316
Name: Piplartine
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C0317
Name: Plumbagin
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C0401
Name: Shikonin
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C0421
Name: Sulforaphane
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C0848
Name: Acetaminophen


Related Herbs  (Total: 58)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0366 Rou Gui肉桂 CassiabarktreeCinnamomum cassia
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0415 Shan Nai山柰 Galanga resurrectionlilyKaempferia galanga
H0295 Bi Ba荜茇 Long pepperPiper longum
H1097 Gong Ding Xiang公丁香 NASyzygium aromaticum
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0572 Tu Huo Xiang土藿香 PatchouliPogostemon cablin
H0763 Yu Mi Xu玉米须 Maize styleZea mays
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0260 Mo Xiang没香 MyrrhCommiphora myrrha
H0005 Huo Xiang Ye藿香叶 PatchouliPogostemon cablin
H0510 Su He Xiang苏合香 Oriental sweetgum resinLiquidambar orientalis
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H1120 Guang Huo Xiang广藿香 PatchouliPogostemon cablin
H0159 Ban Xia Qu半夏曲 Pinellia tuber leavenPinellia ternata
H0155 Ban Xia半夏 Ternate pinelliaPinellia ternata
H1135 Gui Pi桂皮 Japanese cinnamonCinnamomum japonicum
H0367 Rou Gui Ye肉桂叶 Cassia bark oilOleum cinnamomi
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H0126 Lai Fu Zi莱菔子 Garden radish seedRaphanus sativus
H0142 Liang Jiang良姜 NAAlpinia officinarum
H0028 Jiang Huang姜黄 Common turmericCurcuma longa
H0273 Mu Tong木通 Fiveleaf akebiaAkebia quinata
H1093 Gao Liang Jiang You高良姜油 Lesser galangalAlpinia officinarum
H0844 Zi Cao紫草 Redroot gromwellLithospermum erythrorhizon
H0761 Yu Jin郁金 AromaticTurmericCurcuma aromatica
H1139 Gui Zhi桂枝 Cassiabarktree twigCinnamomum cassia
H1092 Gao Liang Jiang高良姜 Lesser galangalAlpinia officinarum
H1136 Gui Pi You桂皮油 Cinnamon oilOleum corticis cinnamomi
H0231 Mao Gao Cai茅膏菜 Lunate peltate sundewDrosera peltata var. lunata
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H0237 Mei Gui Hua玫瑰花 Rugose rose flowerRosa rugosa
H1114 Guan Gui官桂 CassiabarktreeCinnamomum cassia
H1010 Du Huo Xiang杜藿香 PatchouliPogostemon cablin
H0466 Cai Fu Zi菜菔子 Semen raphaniRaphanus sativus
H0556 Tie Xian Cao铁线草 NAAdiantum capillus-veneris
H0895 Chuan Yu Jin川郁金 TurmericCurcuma longa
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0252 Mian Da Ji绵大戟 NAEuphorbia pekinensis
H0747 An Xi Xiang安息香 Sumatra snowbelStyrax benzoin
H0368 Rou Gui Zi肉桂子 CassiabarktreeCinnamomum cassia
H0990 Ding Xiang丁香 Clove treeSyzygium aromaticum
H0125 Lai Fu莱菔 Garden radishRaphanus sativus
H0673 Xin Jiang Zi Cao新疆紫草 Arnebia rootArnebia euchroma
H0261 Mo Yao没药 MyrrhCommiphora myrrha
H1122 Guang Huo Xiang Ye广藿香叶 leaf of cabline potchouliFolium pogostemonis
H0439 Sheng Ban Xia生半夏 Ternate pinelliaPinellia ternata
H0274 Mu Xiang木香 Common aucklandiaSaussurea lappa
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H0576 Tu Mu Xiang土木香 Elecampane inulaInula helenium
H0471 Shou Shen手参 Fragrant orchidGymnadenia conopsea
H0004 Huo Xiang藿香 PatchouliPogostemon cablin
H0986 Dian Zi Cao滇紫草 Paniculate onosmaOnosma paniculatum
H1123 Guang Huo Xiang You广藿香油 oil of cabline potchouliOleum pogostemonis
H0338 Qing Ban Xia清半夏 Ternate pinelliaPinellia ternata
H0941 Da Zao大枣 Chinese dateZiziphus jujuba


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