Target Description

Type Detail
Target ID T24RSX
Protein Name Autophagy protein 5
Uniprot ID Q9H1Y0
Protein Name Alias APG5-like;  Apoptosis-specific protein
Gene ID 9474
Gene Symbol ATG5
Gene Alias APG5L;  ASP
TTD NA
Pfam PF04106
GO
0075044:positive regulation by symbiont of host autophagy

0005776:autophagosome

2000378:negative regulation of reactive oxygen species metabolic process

0039689:negative stranded viral RNA replication

0035973:aggrephagy

0005829:cytosol

0050765:negative regulation of phagocytosis

0044233:mitochondria-associated endoplasmic reticulum membrane

0016236:macroautophagy

0034274:Atg12-Atg5-Atg16 complex

0006501:C-terminal protein lipidation

0005930:axoneme

0006915:apoptotic process

0060548:negative regulation of cell death

0061739:protein lipidation involved in autophagosome assembly

0002718:regulation of cytokine production involved in immune response

0005737:cytoplasm

2000619:negative regulation of histone H4-K16 acetylation

0044804:autophagy of nucleus

0031397:negative regulation of protein ubiquitination

0006995:cellular response to nitrogen starvation

0042311:vasodilation

0071500:cellular response to nitrosative stress

0045060:negative thymic T cell selection

0070257:positive regulation of mucus secretion

0006914:autophagy

0051279:regulation of release of sequestered calcium ion into cytosol

0000422:autophagy of mitochondrion

1902017:regulation of cilium assembly

0001974:blood vessel remodeling

0042493:response to drug

0016020:membrane

0048840:otolith development

0019883:antigen processing and presentation of endogenous antigen

0034045:phagophore assembly site membrane

0000045:autophagosome assembly

0030670:phagocytic vesicle membrane

0055015:ventricular cardiac muscle cell development

0009620:response to fungus

0043687:post-translational protein modification

0043066:negative regulation of apoptotic process

0060047:heart contraction

PDB 5NPW ; 5NPV ; 5D7G ; 4TQ0 ; 4GDL ; 4GDK ; 4NAW ; 4TQ1
Drugbank NA
KEGG hsa:9474

Related Compounds  (Total: 1)

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C0186
Name: Ligustilide


Related Herbs  (Total: 14)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0956 Dang Gui Gan Jin Gao当归干浸膏 NAAngelica sinensis
H0825 Zhu Fu Shen朱茯神 Indian bread with pinePoria cocos
H1090 Gao Ben藁本 Chinese ligusticumLigusticum sinense
H0439 Sheng Ban Xia生半夏 Ternate pinelliaPinellia ternata
H0892 Chuan Xiong川芎 cnidium officinaleCnidium officinale
H1053 Fu Ling茯苓 Indian breadWolfiporia cocos
H0338 Qing Ban Xia清半夏 Ternate pinelliaPinellia ternata
H0955 Dang Gui当归 Chinese angelicaAngelica sinensis
H0773 Chi Fu Ling赤茯苓 light red indian breadWolfiporia cocos
H0672 Xin Jiang Gao Ben新疆藁本 Vaginate hemlockparsleyConioselinum vaginatum
H0155 Ban Xia半夏 Ternate pinelliaPinellia ternata
H0159 Ban Xia Qu半夏曲 Pinellia tuber leavenPinellia ternata
H0273 Mu Tong木通 Fiveleaf akebiaAkebia quinata
H0893 Chuan Xiong Jin Gao川芎浸膏 cnidium officinaleCnidium officinale