Compound Description
| ID: C0186 | Common name: Ligustilide |
| IUPAC: (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one | CAS: CAS:4431-01-0 |
| Chembl ID: CHEMBL481246 | Pubchem ID: CID:5319022 |
| Formula: C12H14O2 | TCM-ID: TCMC1490 |
| Smiles: CCC/C=C/1\OC(=O)C2=C1CCC=C2 | |
| Alias:
1,5-Cyclohexadiene-1-carboxylic acid, 2-(1-hydroxy-1-pentenyl)-, γ-lactone;
Ligustilide; Phthalide, 3-butylidene-4,5-dihydro-; 3-Butylidene-4,5-dihydro-1(3H)-isobenzofuranone; 3-Butylidene-4,5-dihydrophthalide |
Structure:
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Related Targets (Total: 5)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T72U9G | Tumor necrosis factor receptor superfamily member 9 | TNFRSF9 |
Q07011 |
A | 1 Reference(s) |
| T82D6U | Ubiquitin-like protein ATG12 | ATG12 |
O94817 |
C | 1 Reference(s) |
| T24V8E | Ubiquitin-like modifier-activating enzyme ATG7 | ATG7 |
O95352 |
C | 1 Reference(s) |
| T24RSX | Autophagy protein 5 | ATG5 |
Q9H1Y0 |
C | 1 Reference(s) |
| T95EK6 | Microtubule-associated proteins 1A/1B light chain 3B | MAP1LC3B |
Q9GZQ8 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 14)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H0825 | Zhu Fu Shen | 朱茯神 | Indian bread with pine | Poria cocos |
| H1090 | Gao Ben | 藁本 | Chinese ligusticum | Ligusticum sinense |
| H0439 | Sheng Ban Xia | 生半夏 | Ternate pinellia | Pinellia ternata |
| H0892 | Chuan Xiong | 川芎 | cnidium officinale | Cnidium officinale |
| H1053 | Fu Ling | 茯苓 | Indian bread | Wolfiporia cocos |
| H0338 | Qing Ban Xia | 清半夏 | Ternate pinellia | Pinellia ternata |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H0773 | Chi Fu Ling | 赤茯苓 | light red indian bread | Wolfiporia cocos |
| H0672 | Xin Jiang Gao Ben | 新疆藁本 | Vaginate hemlockparsley | Conioselinum vaginatum |
| H0155 | Ban Xia | 半夏 | Ternate pinellia | Pinellia ternata |
| H0159 | Ban Xia Qu | 半夏曲 | Pinellia tuber leaven | Pinellia ternata |
| H0273 | Mu Tong | 木通 | Fiveleaf akebia | Akebia quinata |
| H0893 | Chuan Xiong Jin Gao | 川芎浸膏 | cnidium officinale | Cnidium officinale |
Ckey description of the interaction between compound and target