Target Description

Type Detail
Target ID T24V8E
Protein Name Ubiquitin-like modifier-activating enzyme ATG7
Uniprot ID O95352
Protein Name Alias ATG12-activating enzyme E1 ATG7;  Autophagy-related protein 7;  APG7-like;  hAGP7;  Ubiquitin-activating enzyme E1-like protein
Gene ID 10533
Gene Symbol ATG7
Gene Alias APG7L
TTD T20302: Research target
Pfam PF16420 ; PF00899
GO
0006501:C-terminal protein lipidation

0009749:response to glucose

0019779:Atg8 activating enzyme activity

0034774:secretory granule lumen

0010508:positive regulation of autophagy

0019778:Atg12 activating enzyme activity

0015031:protein transport

0006995:cellular response to nitrogen starvation

0044805:late nucleophagy

0032446:protein modification by small protein conjugation

0039521:suppression by virus of host autophagy

0031401:positive regulation of protein modification process

0005576:extracellular region

0071315:cellular response to morphine

0051607:defense response to virus

0030424:axon

0005829:cytosol

0048511:rhythmic process

0075044:positive regulation by symbiont of host autophagy

0005930:axoneme

0045732:positive regulation of protein catabolic process

1904813:ficolin-1-rich granule lumen

0071455:cellular response to hyperoxia

0090298:negative regulation of mitochondrial DNA replication

0043065:positive regulation of apoptotic process

0009267:cellular response to starvation

0006914:autophagy

0006497:protein lipidation

0042803:protein homodimerization activity

0061684:chaperone-mediated autophagy

0007568:aging

0000045:autophagosome assembly

0043312:neutrophil degranulation

0034727:piecemeal microautophagy of the nucleus

1902617:response to fluoride

0016236:macroautophagy

0005737:cytoplasm

0008134:transcription factor binding

1903204:negative regulation of oxidative stress-induced neuron death

0000422:autophagy of mitochondrion

0042752:regulation of circadian rhythm

0000407:phagophore assembly site

PDB NA
Drugbank NA
KEGG hsa:10533

Related Compounds  (Total: 1)

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C0186
Name: Ligustilide


Related Herbs  (Total: 14)

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H0439 Sheng Ban Xia生半夏 Ternate pinelliaPinellia ternata
H0338 Qing Ban Xia清半夏 Ternate pinelliaPinellia ternata
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