HIT-result

Type	Detail
Target ID	T99HGY
Protein Name	Ubiquitin-protein ligase E3A
Uniprot ID	Q05086
Protein Name Alias	EC 2.3.2.26; E6AP ubiquitin-protein ligase; HECT-type ubiquitin transferase E3A; Human papillomavirus E6-associated protein; Oncogenic protein-associated protein E6-AP; Renal carcinoma antigen NY-REN-54
Gene ID	7337
Gene Symbol	UBE3A
Gene Alias	E6AP; EPVE6AP; HPVE6A
TTD	T87376: Research target
Pfam	PF16558 ; PF00632
GO	0004842:ubiquitin-protein transferase activity 0005634:nucleus 0014068:positive regulation of phosphatidylinositol 3-kinase signaling 0042542:response to hydrogen peroxide 0035037:sperm entry 0006508:proteolysis 0007420:brain development 0070936:protein K48-linked ubiquitination 0003713:transcription coactivator activity 0042752:regulation of circadian rhythm 0051865:protein autoubiquitination 0030521:androgen receptor signaling pathway 0061002:negative regulation of dendritic spine morphogenesis 0006511:ubiquitin-dependent protein catabolic process 0005829:cytosol 0031398:positive regulation of protein ubiquitination 0060736:prostate gland growth 0048511:rhythmic process 1990416:cellular response to brain-derived neurotrophic factor stimulus 0001541:ovarian follicle development 0042220:response to cocaine 0032570:response to progesterone 0016032:viral process 0046872:metal ion binding 1905528:positive regulation of Golgi lumen acidification 0050847:progesterone receptor signaling pathway 0061630:ubiquitin protein ligase activity 0045944:positive regulation of transcription by RNA polymerase II 2000058:regulation of ubiquitin-dependent protein catabolic process 0000502:proteasome complex
PDB	1EQX ; 1C4Z ; 2KR1 ; 6SLM ; 6SJV ; 1D5F ; 4GIZ ; 6U19 ; 6TGK ; 4XR8
Drugbank	NA
KEGG	hsa:7337

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Name: Niacinamide

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0338	Qing Ban Xia	清半夏	Ternate pinellia	Pinellia ternata
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0623	Xi Hong Hua	西红花	Saffron	Stigma croci
H0439	Sheng Ban Xia	生半夏	Ternate pinellia	Pinellia ternata
H0155	Ban Xia	半夏	Ternate pinellia	Pinellia ternata
H0364	Rou Cong Rong	肉苁蓉	Desertliving cistanche	Cistanche deserticola
H0159	Ban Xia Qu	半夏曲	Pinellia tuber leaven	Pinellia ternata
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens