Target Description

Type Detail
Target ID T21PEZ
Protein Name NAD(+) hydrolase SARM1
Uniprot ID Q6SZW1
Protein Name Alias NADase SARM1;  hSARM1;  EC 3.2.2.6;  NADP(+) hydrolase SARM1;  EC 3.2.2.-;  Sterile alpha and Armadillo repeat protein;  Sterile alpha and TIR motif-containing protein 1;  Sterile alpha motif domain-containing protein 2;  MyD88-5;  SAM domain-containing protein 2;  Tir-1 homolog;  HsTIR
Gene ID 23098
Gene Symbol SARM1
Gene Alias KIAA0524;  SAMD2;  SARM
TTD NA
Pfam PF07647 ; PF13676
GO
0042802:identical protein binding

0048814:regulation of dendrite morphogenesis

0042981:regulation of apoptotic process

0030425:dendrite

0030424:axon

0005829:cytosol

0019677:NAD catabolic process

0007399:nervous system development

0061809:NAD+ nucleotidase, cyclic ADP-ribose generating

0005874:microtubule

0035591:signaling adaptor activity

0009749:response to glucose

0005737:cytoplasm

0030154:cell differentiation

1901216:positive regulation of neuron death

0045202:synapse

0003953:NAD+ nucleosidase activity

0005739:mitochondrion

0007165:signal transduction

0050135:NAD(P)+ nucleosidase activity

0031315:extrinsic component of mitochondrial outer membrane

0034128:negative regulation of MyD88-independent toll-like receptor signaling pathway

1901214:regulation of neuron death

0045087:innate immune response

0048678:response to axon injury

PDB 6O0U ; 6O0R ; 6O0Q ; 6O0V ; 6O0T ; 6O0S ; 7ANW ; 7CM5 ; 6ZG0 ; 6ZG1 ; 6ZFX ; 7CM6 ; 6WPK ; 7CM7 ; 6QWV ; 6O1B
Drugbank NA
KEGG hsa:23098

Related Compounds  (Total: 1)

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C0246
Name: Niacinamide


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0159 Ban Xia Qu半夏曲 Pinellia tuber leavenPinellia ternata
H0623 Xi Hong Hua西红花 SaffronStigma croci
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0155 Ban Xia半夏 Ternate pinelliaPinellia ternata
H0439 Sheng Ban Xia生半夏 Ternate pinelliaPinellia ternata
H0364 Rou Cong Rong肉苁蓉 Desertliving cistancheCistanche deserticola
H0338 Qing Ban Xia清半夏 Ternate pinelliaPinellia ternata