HIT-result

Type	Detail
Target ID	T63FF5
Protein Name	Interferon regulatory factor 3
Uniprot ID	Q14653
Protein Name Alias	IRF-3
Gene ID	3661
Gene Symbol	IRF3
Gene Alias	NA
TTD	T38017: Research target
Pfam	PF00605 ; PF10401
GO	0006974:cellular response to DNA damage stimulus 0071888:macrophage apoptotic process 0019904:protein domain specific binding 0032480:negative regulation of type I interferon production 0097300:programmed necrotic cell death 1990837:sequence-specific double-stranded DNA binding 0051607:defense response to virus 0002376:immune system process 0031663:lipopolysaccharide-mediated signaling pathway 0032728:positive regulation of interferon-beta production 0035666:TRIF-dependent toll-like receptor signaling pathway 0039530:MDA-5 signaling pathway 0005829:cytosol 0042981:regulation of apoptotic process 0060333:interferon-gamma-mediated signaling pathway 0042802:identical protein binding 0006915:apoptotic process 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0098586:cellular response to virus 0005654:nucleoplasm 0043565:sequence-specific DNA binding 0032479:regulation of type I interferon production 0005737:cytoplasm 0003677:DNA binding 0000785:chromatin 0005739:mitochondrion 0032727:positive regulation of interferon-alpha production 0045944:positive regulation of transcription by RNA polymerase II 0042803:protein homodimerization activity 0071360:cellular response to exogenous dsRNA 0005634:nucleus 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling 0060340:positive regulation of type I interferon-mediated signaling pathway 0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific 0006357:regulation of transcription by RNA polymerase II 0016032:viral process 0060337:type I interferon signaling pathway 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0032481:positive regulation of type I interferon production 0050727:regulation of inflammatory response
PDB	3QU6 ; 1QWT ; 2O61 ; 5JEJ ; 5JEK ; 6SIV ; 5JER ; 5JEM ; 5JEO ; 7JFL ; 1J2F ; 2O6G ; 3A77 ; 5JEL ; 1ZOQ ; 6SJA ; 2PI0 ; 1T2K
Drugbank	NA
KEGG	hsa:3661

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1097	Gong Ding Xiang	公丁香	NA	Syzygium aromaticum
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0747	An Xi Xiang	安息香	Sumatra snowbel	Styrax benzoin
H0338	Qing Ban Xia	清半夏	Ternate pinellia	Pinellia ternata
H1123	Guang Huo Xiang You	广藿香油	oil of cabline potchouli	Oleum pogostemonis
H0155	Ban Xia	半夏	Ternate pinellia	Pinellia ternata
H0159	Ban Xia Qu	半夏曲	Pinellia tuber leaven	Pinellia ternata
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba
H0189	Lv Cha	绿茶	Green tea	Folium camelliae sinensis
H0261	Mo Yao	没药	Myrrh	Commiphora myrrha
H0941	Da Zao	大枣	Chinese date	Ziziphus jujuba
H0424	Shan Zhi	山栀	Cape jasmine	Gardenia jasminoides
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0673	Xin Jiang Zi Cao	新疆紫草	Arnebia root	Arnebia euchroma
H1004	Bai Cha	白茶	White tea	Camellia sinensis
H0990	Ding Xiang	丁香	Clove tree	Syzygium aromaticum
H1034	Fei Yang Cao	飞杨草	NA	Euphorbia hirta
H0367	Rou Gui Ye	肉桂叶	Cassia bark oil	Oleum cinnamomi
H0368	Rou Gui Zi	肉桂子	Cassiabarktree	Cinnamomum cassia
H1135	Gui Pi	桂皮	Japanese cinnamon	Cinnamomum japonicum
H1122	Guang Huo Xiang Ye	广藿香叶	leaf of cabline potchouli	Folium pogostemonis
H0366	Rou Gui	肉桂	Cassiabarktree	Cinnamomum cassia
H0819	Zhi Zi Jin Gao	栀子浸膏	Cape jasmine fruit	Gardenia jasminoides
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1029	Fang Er Cha	方儿茶	khair in hindi	Senegalia catechu
H0273	Mu Tong	木通	Fiveleaf akebia	Akebia quinata
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H1114	Guan Gui	官桂	Cassiabarktree	Cinnamomum cassia
H0439	Sheng Ban Xia	生半夏	Ternate pinellia	Pinellia ternata
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H0510	Su He Xiang	苏合香	Oriental sweetgum resin	Liquidambar orientalis
H0415	Shan Nai	山柰	Galanga resurrectionlily	Kaempferia galanga
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0844	Zi Cao	紫草	Redroot gromwell	Lithospermum erythrorhizon
H1055	Bai Guo Ren	白果仁	ginkgo	Ginkgo biloba
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0260	Mo Xiang	没香	Myrrh	Commiphora myrrha
H1136	Gui Pi You	桂皮油	Cinnamon oil	Oleum corticis cinnamomi
H0750	Yin Xing Ye	银杏叶	Folium ginkgo	Ginkgo biloba
H0637	Cha Ye	茶叶	Common tea	Camellia sinensis
H0166	Long Kui	龙葵	Black nightshade	Solanum nigrum
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H1139	Gui Zhi	桂枝	Cassiabarktree twig	Cinnamomum cassia
H0721	Yang Mei Gen	杨梅根	Myrica rubra sieb. et zucc	Myrica rubra
H0237	Mei Gui Hua	玫瑰花	Rugose rose flower	Rosa rugosa
H0692	Xue Ren Shen	血人参	NA	Lespedeza bicolor

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 49)