HIT-result

Target Description

Type	Detail
Target ID	T37V37
Protein Name	Prostaglandin-H2 D-isomerase
Uniprot ID	P41222
Protein Name Alias	EC 5.3.99.2; Beta-trace protein; Cerebrin-28; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; L-PGDS; Prostaglandin-D2 synthase; PGD2 synthase; PGDS; PGDS2
Gene ID	5730
Gene Symbol	PTGDS
Gene Alias	PDS
TTD	NA
Pfam	PF00061
GO	0019371:cyclooxygenase pathway 0001516:prostaglandin biosynthetic process 0031965:nuclear membrane 0070062:extracellular exosome 0005791:rough endoplasmic reticulum 0005789:endoplasmic reticulum membrane 0004667:prostaglandin-D synthase activity 0005615:extracellular space 0005504:fatty acid binding 0036094:small molecule binding 0045187:regulation of circadian sleep/wake cycle, sleep 0043303:mast cell degranulation 0005501:retinoid binding 0005576:extracellular region 0005794:Golgi apparatus 0048471:perinuclear region of cytoplasm
PDB	2WWP ; 4IMN ; 4ORY ; 4OS8 ; 4ORS ; 4ORU ; 3O22 ; 4ORW ; 4OS0 ; 4IMO ; 4ORR ; 4OS3 ; 3O19 ; 3O2Y ; 5WY9 ; 4ORX
Drugbank	DB00162
KEGG	hsa:5730

Type

Detail

Target ID

T37V37

Protein Name

Prostaglandin-H2 D-isomerase

Uniprot ID

P41222

Protein Name Alias

EC 5.3.99.2; Beta-trace protein; Cerebrin-28; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; L-PGDS; Prostaglandin-D2 synthase; PGD2 synthase; PGDS; PGDS2

Gene ID

5730

Gene Symbol

PTGDS

Gene Alias

PDS

TTD

Pfam

PF00061

0019371:cyclooxygenase pathway

0001516:prostaglandin biosynthetic process

0031965:nuclear membrane

0070062:extracellular exosome

0005791:rough endoplasmic reticulum

0005789:endoplasmic reticulum membrane

0004667:prostaglandin-D synthase activity

0005615:extracellular space

0005504:fatty acid binding

0036094:small molecule binding

0045187:regulation of circadian sleep/wake cycle, sleep

0043303:mast cell degranulation

0005501:retinoid binding

0005576:extracellular region

0005794:Golgi apparatus

0048471:perinuclear region of cytoplasm

PDB

2WWP ; 4IMN ; 4ORY ; 4OS8 ; 4ORS ; 4ORU ; 3O22 ; 4ORW ; 4OS0 ; 4IMO ; 4ORR ; 4OS3 ; 3O19 ; 3O2Y ; 5WY9 ; 4ORX

Drugbank

DB00162

KEGG

hsa:5730

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Name: Niacinamide

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Name: Prostaglandin D2

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Name: Aldosterone

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0338	Qing Ban Xia	清半夏	Ternate pinellia	Pinellia ternata
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0623	Xi Hong Hua	西红花	Saffron	Stigma croci
H0439	Sheng Ban Xia	生半夏	Ternate pinellia	Pinellia ternata
H0155	Ban Xia	半夏	Ternate pinellia	Pinellia ternata
H0364	Rou Cong Rong	肉苁蓉	Desertliving cistanche	Cistanche deserticola
H0159	Ban Xia Qu	半夏曲	Pinellia tuber leaven	Pinellia ternata
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 9)