Target Description

Type Detail
Target ID T10MFU
Protein Name DCC-interacting protein 13-beta
Uniprot ID Q8NEU8
Protein Name Alias Dip13-beta;  Adapter protein containing PH domain, PTB domain and leucine zipper motif 2
Gene ID 55198
Gene Symbol APPL2
Gene Alias DIP13B
TTD NA
Pfam PF00169 ; PF00640
GO
0042802:identical protein binding

0005634:nucleus

0060100:positive regulation of phagocytosis, engulfment

0045088:regulation of innate immune response

0070062:extracellular exosome

0007179:transforming growth factor beta receptor signaling pathway

0120162:positive regulation of cold-induced thermogenesis

0044354:macropinosome

0031410:cytoplasmic vesicle

0046322:negative regulation of fatty acid oxidation

1900077:negative regulation of cellular response to insulin stimulus

0001726:ruffle

0051289:protein homotetramerization

0046325:negative regulation of glucose import

0007049:cell cycle

0050768:negative regulation of neurogenesis

0035729:cellular response to hepatocyte growth factor stimulus

0034143:regulation of toll-like receptor 4 signaling pathway

0006606:protein import into nucleus

0044877:protein-containing complex binding

0009631:cold acclimation

0036186:early phagosome membrane

0005886:plasma membrane

2000045:regulation of G1/S transition of mitotic cell cycle

0031982:vesicle

0002024:diet induced thermogenesis

0033211:adiponectin-activated signaling pathway

0016020:membrane

0031901:early endosome membrane

0001786:phosphatidylserine binding

0032587:ruffle membrane

2000178:negative regulation of neural precursor cell proliferation

0023052:signaling

0042803:protein homodimerization activity

1905303:positive regulation of macropinocytosis

0007165:signal transduction

0042593:glucose homeostasis

1905451:positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

0035091:phosphatidylinositol binding

0010762:regulation of fibroblast migration

1900016:negative regulation of cytokine production involved in inflammatory response

0005768:endosome

0032009:early phagosome

0010008:endosome membrane

PDB 5C5B ; 4H8S
Drugbank NA
KEGG hsa:55198

Related Compounds  (Total: 1)

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C0721
Name: Baicalin


Related Herbs  (Total: 1)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0155 Ban Xia半夏 Ternate pinelliaPinellia ternata