HIT-result

Type	Detail
Target ID	T69CTT
Protein Name	Acetyl-CoA acetyltransferase, mitochondrial
Uniprot ID	P24752
Protein Name Alias	EC 2.3.1.9; Acetoacetyl-CoA thiolase; T2
Gene ID	38
Gene Symbol	ACAT1
Gene Alias	ACAT; MAT
TTD	T11487: Clinical Trial target
Pfam	PF00108 ; PF02803
GO	0030955:potassium ion binding 0070062:extracellular exosome 0006085:acetyl-CoA biosynthetic process 0005739:mitochondrion 0009083:branched-chain amino acid catabolic process 0015936:coenzyme A metabolic process 0016453:C-acetyltransferase activity 1902860:propionyl-CoA biosynthetic process 0003985:acetyl-CoA C-acetyltransferase activity 0046951:ketone body biosynthetic process 0005759:mitochondrial matrix 0034435:cholesterol esterification 0006550:isoleucine catabolic process 0046952:ketone body catabolic process 0015937:coenzyme A biosynthetic process 0046356:acetyl-CoA catabolic process 1902224:ketone body metabolic process 0006635:fatty acid beta-oxidation
PDB	2IB7 ; 2F2S ; 2IBW ; 2IB9 ; 2IBU ; 2IBY ; 2IB8
Drugbank	DB09061 ; DB14011 ; DB14009 ; DB00795
KEGG	hsa:38

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0609	Wu Wei Zi Liu Jin Gao	五味子流浸膏	Five-flavor berry	Schisandra chinensis
H0648	Xiang Si Teng	相思藤	Coralhead plant vine	Abrus precatorius
H0605	Wu Wei Zi	五味子	Chinese magnoliavine	Schisandra chinensis
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0606	Wu Wei Zi Chun Jin Gao	五味子醇浸膏	Five-flavor berry	Schisandra chinensis
H1226	Huai Shan Yao	淮山药	rhizome of biglcaf yam	Rhizoma dioscoreae
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0608	Wu Wei Zi Jin Gao	五味子浸膏	Five-flavor berry	Schisandra chinensis
H0735	Yi Bei Mu	伊贝母	Siberian fritillary equivalent plant: fritillaria walujewii	Fritillaria pallidiflora
H0838	Zhu Zi Shen	珠子参	Largeleaf japanese ginseng rhizome	Rhizoma panacis majoris
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0607	Wu Wei Zi Jin Chu Wu	五味子浸出物	Five-flavor berry	Schisandra chinensis
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0649	Xiang Si Zi	相思子	Coralhead plant	Abrus precatorius
H0287	Nao Yang Hua	闹羊花	Chinese azalea	Rhododendron molle

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 24)