HIT-result

Target Description

Type	Detail
Target ID	T02GMU
Protein Name	Lysosome-associated membrane glycoprotein 2
Uniprot ID	P13473
Protein Name Alias	LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; LGP-96; CD antigen CD107b
Gene ID	3920
Gene Symbol	LAMP2
Gene Alias	NA
TTD	T46052: Clinical Trial target
Pfam	PF01299
GO	0070062:extracellular exosome 0005770:late endosome 0061740:protein targeting to lysosome involved in chaperone-mediated autophagy 0061684:chaperone-mediated autophagy 0044754:autolysosome 0061742:chaperone-mediated autophagy translocation complex 0019904:protein domain specific binding 1990836:lysosomal matrix 0046716:muscle cell cellular homeostasis 0097637:integral component of autophagosome membrane 0005765:lysosomal membrane 0097352:autophagosome maturation 0005615:extracellular space 0072594:establishment of protein localization to organelle 0035577:azurophil granule membrane 0005886:plasma membrane 0048471:perinuclear region of cytoplasm 0019899:enzyme binding 0005764:lysosome 0045121:membrane raft 1905146:lysosomal protein catabolic process 0050821:protein stabilization 0043312:neutrophil degranulation 0016020:membrane 0043202:lysosomal lumen 0031333:negative regulation of protein-containing complex assembly 0031088:platelet dense granule membrane 0031902:late endosome membrane 0006605:protein targeting 0101003:ficolin-1-rich granule membrane 0030670:phagocytic vesicle membrane 0017038:protein import 0031647:regulation of protein stability 0005802:trans-Golgi network 0002576:platelet degranulation 0009267:cellular response to starvation
PDB	2MOF ; 2MOM
Drugbank	NA
KEGG	hsa:3920

Type

Detail

Target ID

T02GMU

Protein Name

Lysosome-associated membrane glycoprotein 2

Uniprot ID

P13473

Protein Name Alias

LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; LGP-96; CD antigen CD107b

Gene ID

3920

Gene Symbol

LAMP2

Gene Alias

TTD

T46052: Clinical Trial target

Pfam

PF01299

0070062:extracellular exosome

0005770:late endosome

0061740:protein targeting to lysosome involved in chaperone-mediated autophagy

0061684:chaperone-mediated autophagy

0044754:autolysosome

0061742:chaperone-mediated autophagy translocation complex

0019904:protein domain specific binding

1990836:lysosomal matrix

0046716:muscle cell cellular homeostasis

0097637:integral component of autophagosome membrane

0005765:lysosomal membrane

0097352:autophagosome maturation

0005615:extracellular space

0072594:establishment of protein localization to organelle

0035577:azurophil granule membrane

0005886:plasma membrane

0048471:perinuclear region of cytoplasm

0019899:enzyme binding

0005764:lysosome

0045121:membrane raft

1905146:lysosomal protein catabolic process

0050821:protein stabilization

0043312:neutrophil degranulation

0016020:membrane

0043202:lysosomal lumen

0031333:negative regulation of protein-containing complex assembly

0031088:platelet dense granule membrane

0031902:late endosome membrane

0006605:protein targeting

0101003:ficolin-1-rich granule membrane

0030670:phagocytic vesicle membrane

0017038:protein import

0031647:regulation of protein stability

0005802:trans-Golgi network

0002576:platelet degranulation

0009267:cellular response to starvation

PDB

2MOF ; 2MOM

Drugbank

KEGG

hsa:3920

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0607	Wu Wei Zi Jin Chu Wu	五味子浸出物	Five-flavor berry	Schisandra chinensis
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0735	Yi Bei Mu	伊贝母	Siberian fritillary equivalent plant: fritillaria walujewii	Fritillaria pallidiflora
H0605	Wu Wei Zi	五味子	Chinese magnoliavine	Schisandra chinensis
H0648	Xiang Si Teng	相思藤	Coralhead plant vine	Abrus precatorius
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0606	Wu Wei Zi Chun Jin Gao	五味子醇浸膏	Five-flavor berry	Schisandra chinensis
H1226	Huai Shan Yao	淮山药	rhizome of biglcaf yam	Rhizoma dioscoreae
H0287	Nao Yang Hua	闹羊花	Chinese azalea	Rhododendron molle
H0809	Zhi Mu	知母	Common anemarrhena	Anemarrhena asphodeloides
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0609	Wu Wei Zi Liu Jin Gao	五味子流浸膏	Five-flavor berry	Schisandra chinensis
H0697	Ya Ma Zi	亚麻子	Common flax seed	Linum usitatissimum
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0608	Wu Wei Zi Jin Gao	五味子浸膏	Five-flavor berry	Schisandra chinensis
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0649	Xiang Si Zi	相思子	Coralhead plant	Abrus precatorius
H0476	Can E	蚕蛾	Silkworm	Bombyx mori

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 23)