Target Description
| Type | Detail |
|---|---|
| Target ID | T50MQN |
| Protein Name | NPC1-like intracellular cholesterol transporter 1 |
| Uniprot ID |
Q9UHC9 |
| Protein Name Alias | Niemann-Pick C1-like protein 1 |
| Gene ID |
29881 |
| Gene Symbol | NPC1L1 |
| Gene Alias | NA |
| TTD | T33901: Successful target |
| Pfam | PF16414 ; PF12349 ; PF02460 |
| GO |
0031526:brush border membrane
0098856:intestinal lipid absorption 0030299:intestinal cholesterol absorption 0030659:cytoplasmic vesicle membrane 0042493:response to drug 0044214:spanning component of plasma membrane 0008144:drug binding 0042157:lipoprotein metabolic process 0014850:response to muscle activity 0031267:small GTPase binding 0031489:myosin V binding 0071501:cellular response to sterol depletion 0030301:cholesterol transport 0006695:cholesterol biosynthetic process 0016324:apical plasma membrane 0005886:plasma membrane |
| PDB | 3QNT |
| Drugbank | DB00163 ; DB11635 ; DB00973 |
| KEGG | hsa:29881 |
Related Compounds (Total: 3)
C0554
Name: Cholesterol
C0739
Name: (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione
C1234
Name: Cholesterol
Related Herbs (Total: 29)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
| H0500 | Can Yong | 蚕蛹 | Silkworm chrysalis | Bombyx mori |
| H1134 | Bai Jiang Can | 白僵蚕 | Silkworm larva | Bombyx mori |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0287 | Nao Yang Hua | 闹羊花 | Chinese azalea | Rhododendron molle |
| H0648 | Xiang Si Teng | 相思藤 | Coralhead plant vine | Abrus precatorius |
| H0490 | Can Jian | 蚕茧 | Silk cocoon | Bombyx mori |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0649 | Xiang Si Zi | 相思子 | Coralhead plant | Abrus precatorius |
| H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0495 | Can Sha | 蚕砂 | Silkworm excrement | Bombyx mori |
| H1226 | Huai Shan Yao | 淮山药 | rhizome of biglcaf yam | Rhizoma dioscoreae |
| H0838 | Zhu Zi Shen | 珠子参 | Largeleaf japanese ginseng rhizome | Rhizoma panacis majoris |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0697 | Ya Ma Zi | 亚麻子 | Common flax seed | Linum usitatissimum |
| H0556 | Tie Xian Cao | 铁线草 | NA | Adiantum capillus-veneris |
| H0895 | Chuan Yu Jin | 川郁金 | Turmeric | Curcuma longa |
| H0809 | Zhi Mu | 知母 | Common anemarrhena | Anemarrhena asphodeloides |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0761 | Yu Jin | 郁金 | AromaticTurmeric | Curcuma aromatica |
| H0028 | Jiang Huang | 姜黄 | Common turmeric | Curcuma longa |
| H0476 | Can E | 蚕蛾 | Silkworm | Bombyx mori |
| H0484 | Shui Fei Ji | 水飞蓟 | St marys | Silybum marianum |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
| H0735 | Yi Bei Mu | 伊贝母 | Siberian fritillary equivalent plant: fritillaria walujewii | Fritillaria pallidiflora |