Target Description

Type Detail
Target ID T67U3B
Protein Name Translocator protein
Uniprot ID P30536
Protein Name Alias Mitochondrial benzodiazepine receptor;  PKBS;  Peripheral-type benzodiazepine receptor;  PBR
Gene ID 706
Gene Symbol TSPO
Gene Alias BZRP;  MBR
TTD T75440: Successful target
Pfam PF03073
GO
0005741:mitochondrial outer membrane

0033574:response to testosterone

0042127:regulation of cell population proliferation

0008503:benzodiazepine receptor activity

0005829:cytosol

0010042:response to manganese ion

0014012:peripheral nervous system axon regeneration

0005497:androgen binding

0006783:heme biosynthetic process

0031397:negative regulation of protein ubiquitination

0032720:negative regulation of tumor necrosis factor production

0008202:steroid metabolic process

0043231:intracellular membrane-bounded organelle

0006700:C21-steroid hormone biosynthetic process

0032374:regulation of cholesterol transport

1903579:negative regulation of ATP metabolic process

0044325:ion channel binding

0005783:endoplasmic reticulum

0071476:cellular hypotonic response

0008347:glial cell migration

0070062:extracellular exosome

0016021:integral component of membrane

0045019:negative regulation of nitric oxide biosynthetic process

0006820:anion transport

0015485:cholesterol binding

0051928:positive regulation of calcium ion transport

0032570:response to progesterone

0060253:negative regulation of glial cell proliferation

0043065:positive regulation of apoptotic process

0048266:behavioral response to pain

0006869:lipid transport

1903147:negative regulation of autophagy of mitochondrion

0071222:cellular response to lipopolysaccharide

2000379:positive regulation of reactive oxygen species metabolic process

0072656:maintenance of protein location in mitochondrion

0006821:chloride transport

0051901:positive regulation of mitochondrial depolarization

0006626:protein targeting to mitochondrion

0042493:response to drug

0007568:aging

0010940:positive regulation of necrotic cell death

0060252:positive regulation of glial cell proliferation

0071294:cellular response to zinc ion

0010266:response to vitamin B1

0060242:contact inhibition

0050810:regulation of steroid biosynthetic process

0005739:mitochondrion

0030325:adrenal gland development

PDB NA
Drugbank DB01178 ; DB01198
KEGG hsa:706

Related Compounds  (Total: 5)

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C0554
Name: Cholesterol
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C0565
Name: Fructose
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C0568
Name: Fructose
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C1135
Name: ginkgolide b
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C1234
Name: Cholesterol


Related Herbs  (Total: 32)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0500 Can Yong蚕蛹 Silkworm chrysalisBombyx mori
H1134 Bai Jiang Can白僵蚕 Silkworm larvaBombyx mori
H0607 Wu Wei Zi Jin Chu Wu五味子浸出物 Five-flavor berrySchisandra chinensis
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0287 Nao Yang Hua闹羊花 Chinese azaleaRhododendron molle
H0417 Shan Yao山药 Common yamDioscorea batatas
H0648 Xiang Si Teng相思藤 Coralhead plant vineAbrus precatorius
H0490 Can Jian蚕茧 Silk cocoonBombyx mori
H0605 Wu Wei Zi五味子 Chinese magnoliavineSchisandra chinensis
H0649 Xiang Si Zi相思子 Coralhead plantAbrus precatorius
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0609 Wu Wei Zi Liu Jin Gao五味子流浸膏 Five-flavor berrySchisandra chinensis
H1200 Bai Mao Gen白茅根 Lalang grass rhizomeImperata cylindrica
H0227 Mang Guo Ye芒果叶 Mango leafMangifera indica
H0495 Can Sha蚕砂 Silkworm excrementBombyx mori
H0104 Bai Zhu白术 Largehead atractylodesAtractylodes macrocephala
H1226 Huai Shan Yao淮山药 rhizome of biglcaf yamRhizoma dioscoreae
H0838 Zhu Zi Shen珠子参 Largeleaf japanese ginseng rhizomeRhizoma panacis majoris
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0809 Zhi Mu知母 Common anemarrhenaAnemarrhena asphodeloides
H0606 Wu Wei Zi Chun Jin Gao五味子醇浸膏 Five-flavor berrySchisandra chinensis
H0972 Di Huang地黄 RehmanniaeRehmannia glutinosa
H0427 Shan Zhu Yu山茱萸 Asiatic cornelian cherryCornus officinalis
H0476 Can E蚕蛾 SilkwormBombyx mori
H0484 Shui Fei Ji水飞蓟 St marysSilybum marianum
H0608 Wu Wei Zi Jin Gao五味子浸膏 Five-flavor berrySchisandra chinensis
H0735 Yi Bei Mu伊贝母 Siberian fritillary equivalent plant: fritillaria walujewiiFritillaria pallidiflora
H0537 Tian Dong天冬 Cochinchinese asparagus rootAsparagus cochinchinensis