HIT-result

Target Description

Type	Detail
Target ID	T77ERW
Protein Name	Protein disulfide-isomerase A3
Uniprot ID	P30101
Protein Name Alias	EC 5.3.4.1; 58 kDa glucose-regulated protein; 58 kDa microsomal protein; p58; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 57; ER protein 57; ERp57; Endoplasmic reticulum resident protein 60; ER protein 60; ERp60
Gene ID	2923
Gene Symbol	PDIA3
Gene Alias	ERP57; ERP60; GRP58
TTD	NA
Pfam	PF00085
GO	0042802:identical protein binding 0005634:nucleus 0015037:peptide disulfide oxidoreductase activity 0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 0070062:extracellular exosome 0004629:phospholipase C activity 0034976:response to endoplasmic reticulum stress 0045335:phagocytic vesicle 0005925:focal adhesion 0034975:protein folding in endoplasmic reticulum 0004197:cysteine-type endopeptidase activity 0006457:protein folding 0002474:antigen processing and presentation of peptide antigen via MHC class I 0005615:extracellular space 0005783:endoplasmic reticulum 0015036:disulfide oxidoreductase activity 0098761:cellular response to interleukin-7 0003723:RNA binding 0055038:recycling endosome membrane 0009986:cell surface 0042470:melanosome 0003756:protein disulfide isomerase activity 2001238:positive regulation of extrinsic apoptotic signaling pathway 0042824:MHC class I peptide loading complex 0005788:endoplasmic reticulum lumen
PDB	6ENY ; 2H8L ; 3F8U ; 2ALB ; 2DMM
Drugbank	DB01593 ; DB14533 ; DB09130 ; DB14487 ; DB14548
KEGG	hsa:2923

Type

Detail

Target ID

T77ERW

Protein Name

Protein disulfide-isomerase A3

Uniprot ID

P30101

Protein Name Alias

EC 5.3.4.1; 58 kDa glucose-regulated protein; 58 kDa microsomal protein; p58; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 57; ER protein 57; ERp57; Endoplasmic reticulum resident protein 60; ER protein 60; ERp60

Gene ID

2923

Gene Symbol

PDIA3

Gene Alias

ERP57; ERP60; GRP58

TTD

Pfam

PF00085

0042802:identical protein binding

0005634:nucleus

0015037:peptide disulfide oxidoreductase activity

0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0070062:extracellular exosome

0004629:phospholipase C activity

0034976:response to endoplasmic reticulum stress

0045335:phagocytic vesicle

0005925:focal adhesion

0034975:protein folding in endoplasmic reticulum

0004197:cysteine-type endopeptidase activity

0006457:protein folding

0002474:antigen processing and presentation of peptide antigen via MHC class I

0005615:extracellular space

0005783:endoplasmic reticulum

0015036:disulfide oxidoreductase activity

0098761:cellular response to interleukin-7

0003723:RNA binding

0055038:recycling endosome membrane

0009986:cell surface

0042470:melanosome

0003756:protein disulfide isomerase activity

2001238:positive regulation of extrinsic apoptotic signaling pathway

0042824:MHC class I peptide loading complex

0005788:endoplasmic reticulum lumen

PDB

6ENY ; 2H8L ; 3F8U ; 2ALB ; 2DMM

Drugbank

DB01593 ; DB14533 ; DB09130 ; DB14487 ; DB14548

KEGG

hsa:2923

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0648	Xiang Si Teng	相思藤	Coralhead plant vine	Abrus precatorius
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H1186	Hong Gen Cao	红根草	Hispid sage	Salvia prionitis
H1170	He Zi	诃子	Medicine terminalia	Terminalia chebula
H0818	Zhi Zi	栀子	Cape jasmine fruit	Gardenia jasminoides
H1007	Dou You	豆油	Soybean oil	Glycine max
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H0424	Shan Zhi	山栀	Cape jasmine	Gardenia jasminoides
H0819	Zhi Zi Jin Gao	栀子浸膏	Cape jasmine fruit	Gardenia jasminoides
H0075	Jing Mi	粳米	Rice	Oryza sativa
H0464	Shi Liu Zi	石榴子	NA	Punica granatum
H0702	Yan Bai Cai	岩白菜	Purple bergenia	Bergenia purpurascens
H0026	Jiang	姜	Soybean paste	Glycine max
H1193	Hou Er Huan Gan Jin Gao	猴耳环干浸膏	NA	Pithecellobium clypearia
H1194	Hou Er Huan Jin Gao	猴耳环浸膏	NA	Pithecellobium clypearia
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H0060	Jin Si Ku Lian	金丝苦楝	NA	Cardiospermum halicacabum
H0461	Shi Jun Zi Ren	使君子仁	NA	Combretum indicum
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H1192	Hou Er Huan	猴耳环	NA	Pithecellobium clypearia
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H1171	He Zi Rou	诃子肉	Medicine terminalia	Terminalia chebula
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H0547	Cang Qing Guo	藏青果	Myrobalan	Terminalia chebula
H0649	Xiang Si Zi	相思子	Coralhead plant	Abrus precatorius

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 27)