HIT-result

Type	Detail
Target ID	T16UHV
Protein Name	Nuclear factor of activated T-cells, cytoplasmic 1
Uniprot ID	O95644
Protein Name Alias	NF-ATc1; NFATc1; NFAT transcription complex cytosolic component; NF-ATc; NFATc
Gene ID	4772
Gene Symbol	NFATC1
Gene Alias	NFAT2; NFATC
TTD	NA
Pfam	PF00554 ; PF16179
GO	0005667:transcription regulator complex 0035556:intracellular signal transduction 0007223:Wnt signaling pathway, calcium modulating pathway 1990837:sequence-specific double-stranded DNA binding 0008134:transcription factor binding 0001225:RNA polymerase II transcription coactivator binding 0016604:nuclear body 0038095:Fc-epsilon receptor signaling pathway 0005829:cytosol 0003184:pulmonary valve morphogenesis 0001228:DNA-binding transcription activator activity, RNA polymerase II-specific 0033173:calcineurin-NFAT signaling cascade 0048273:mitogen-activated protein kinase p38 binding 0005654:nucleoplasm 0005737:cytoplasm 0045893:positive regulation of transcription, DNA-templated 0005528:FK506 binding 0000785:chromatin 0003700:DNA-binding transcription factor activity 0045944:positive regulation of transcription by RNA polymerase II 0005634:nucleus 0001085:RNA polymerase II transcription factor binding 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0006357:regulation of transcription by RNA polymerase II 1905064:negative regulation of vascular associated smooth muscle cell differentiation 0003180:aortic valve morphogenesis 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0030178:negative regulation of Wnt signaling pathway
PDB	5SVE ; 1A66 ; 1NFA
Drugbank	DB00852
KEGG	hsa:4772

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H1227	Huai Zhi	槐枝	NA	Sophora japonica
H0651	Xiang Yuan	香橼	Wilson citron	Citrus medica
H1015	Du Zhong	杜仲	Eucommia	Eucommia ulmoides
H0937	Da Qing Ye	大青叶	Indigo-coloured woad leaf	Isatis indigotica
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H1254	Huang Qin Tan	黄芩炭	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H1217	Bai Mei Hua	白梅花	Japanese apricot flower	Prunus mume
H1164	He Geng	荷梗	Hindu lotus petiole	Nelumbo nucifera
H0429	Shao Yao	芍药	Red peony root	Paeonia obovata
H0644	Xiang Mao	香茅	Lemongrass	Cymbopogon citratus
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H0153	Ling Zhi(1)	灵芝	Lucid ganoderma	Ganoderma lucidum
H1251	Huang Qin	黄芩	Root of Baikal skullcaap	Scutellaria baicalensis
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin
H0310	Pian Qin	片芩	Scutellaria amoena	Scutellaria baicalensis
H0130	Lei Gong Teng	雷公藤	Common threewingnut	Tripterygium wilfordii
H0667	Xiao Qing Pi	小青皮	Green tangerine peel	Pericarpium citri reticulatae viride
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H0904	Ci Ji Li	刺蒺藜	Puncturevine caltrap	Tribulus terrestris
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0530	Tao Ren Shuang	桃仁霜	Peach kernel	Prunus persica
H0887	Chuan Xin Lian Gan Jin Gao	穿心莲干浸膏	Common andrographis	Andrographis paniculata
H0301	Ou	藕	Hindu lotus large rhizome	Nelumbo nucifera
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0137	Ban Lan Gen	板蓝根	Indigowoad root	Isatis indigotica
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H1102	Gu Sui Bu	骨碎补	Fortune’s drynaria rhizome	Drynaria fortunei
H0011	Ji Li	蒺藜	Puncturevine caltrop fruit	Tribulus terrestris
H1222	Huai Hua	槐花	flower bud of japanese pagodatree	Sophora japonica
H0531	Tao Zhi	桃枝	Peach juvenile branch	Prunus persica
H0131	Ban Lan	板蓝	Indigowoad root	Isatis indigotica
H1224	Huai Jiao	槐角	pod of japanese pagodatree	Sophora japonica
H0347	Qing Pi	青皮	Green tangerine peel	Pericarpium citri reticulatae viride
H1169	He Ye	荷叶	Hindu lotus leaf	Nelumbo nucifera
H0141	Lian Zi Xin	莲子心	Hindu lotus plumule	Nelumbo nucifera
H0089	Ju Hong	橘红	NA	Citri exocarpium rubrum
H0339	Qing Dai	青黛	Natural indigo	Indigo naturalis
H0527	Tao	桃	Peach	Prunus persica
H0889	Chuan Xin Lian Jin Gao	穿心莲浸膏	Common andrographis	Andrographis paniculata
H0046	Jin Gan	金柑	Japanese kumquat	Fortunella japonica
H1252	Huang Qin Jin Gao	黄芩浸膏	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H1121	Bai Ji Li	白蒺藜	Tribulus fruit	Tribulus terrestris
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H1016	Du Zhong Tan	杜仲炭	Eucommia	Eucommia ulmoides
H0604	Wu Wei Teng	五味藤	NA	Securidaca inappendiculata
H0602	Wu Mei Rou	乌梅肉	Ebony	Prunus mume
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0052	Jin Ju	金橘	Oval kumquat	Fortunella margarita
H1017	Du Zhong Ye	杜仲叶	Eucommia leaf	Eucommia ulmoides
H0304	Ou Pian	藕片	Hindu lotus large rhizome	Nelumbo nucifera
H1247	Huang Qi	黄芪	Membranous milkvetch	Astragalus membranaceus
H0976	Di Qing Pi	地青皮	NA	Pericarpium citri reticulatae viride
H0886	Chuan Xin Lian	穿心莲	Common andrographis	Andrographis paniculata
H0302	Ou Fen	藕粉	Hindu lotus large rhizome	Nelumbo nucifera
H0784	Chi Shao	赤芍	Red peony root	Paeonia obovata
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0719	Chen Pi	陈皮	Dried tangerine peel	Pericarpium citri reticulatae
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H1253	Huang Qin Jin Gao Fen	黄芩浸膏粉	Extract of root of Baikal skullcaap	Scutellaria baicalensis
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0164	Ban Zhi Lian	半枝莲	Barbed skullcap	Scutellaria barbata
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0601	Wu Mei	乌梅	Japanese apricot	Prunus mume
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum
H1215	Hua Ju Hong	化橘红	Pummelo peel	Exocarpium citri grandis
H0652	Xiang Yuan Pi	香橼皮	Wilson citron	Citrus medica
H1225	Huai Mi	槐米	NA	Sophora japonica
H0890	Chuan Xin Lian Nong Suo Ye	穿心莲浓缩液	Common andrographis	Andrographis paniculata
H1250	Huang Qi Ti Qu Ye	黄芪提取液	Membranous milkvetch	Astragalus membranaceus
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H0529	Tao Ren	桃仁	Peach kernel	Prunus persica
H0265	Mu Da Qing Ye	木大青叶	Indigo-coloured woad leaf equivalent	Isatis indigotica
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0091	Ju Hong Pi	橘红皮	Red tangerine peel	Exocarpium citri rubrum
H0140	Lian Zi	莲子	Hindu lotus seed	Nelumbo nucifera
H0263	Mu Ban Lan Gen	木板蓝根	Indigowoad root	Isatis indigotica
H0192	Lv Yi Zhi Shi	绿衣枳实	NA	Poncirus trifoliata
H0467	Shi Shang Bai	石上柏	Doederlein's spikemoss herb	Herba selaginellae doederleinii
H0324	Qian Jin Ba	千斤拔	root of philippine flemingia	Radix moghaniae philippinensis
H1249	Huang Qi Jin Gao	黄芪浸膏	Membranous milkvetch	Astragalus membranaceus
H1248	Huang Qi Gan Jin Gao	黄芪干浸膏	Membranous milkvetch	Astragalus membranaceus
H0152	Ling Zhi Jin Gao	灵芝浸膏	NA	Ganoderma lucidum
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium

Target Description

Related Compounds (Total: 8)

Related Herbs (Total: 96)