HIT-result

Target id	Protein Name	Gene Symbol	Uniprot ID	No.of Literature Evidence
T49TDM	Matrix metalloproteinase-9	MMP9	P14780	3 Reference(s)
T75PC7	NA	MIR21	NA	2 Reference(s)
T88AJI	Hypoxia-inducible factor 1-alpha	HIF1A	Q16665	7 Reference(s)
T06RMZ	Nuclear factor NF-kappa-B p105 subunit	NFKB1	P19838	12 Reference(s)
T11BI7	Toll-like receptor 4	TLR4	O00206	4 Reference(s)
T36Y8O	Fanconi anemia group D2 protein	FANCD2	Q9BXW9	2 Reference(s)
T02QBS	Cytochrome P450 1A2	CYP1A2	P05177	2 Reference(s)
T47H3O	Heat shock protein HSP 90-alpha	HSP90AA1	P07900	7 Reference(s)
T96OOK	Signal transducer and activator of transcription 3	STAT3	P40763	2 Reference(s)
T28I32	Nuclear receptor subfamily 2 group C member 2	NR2C2	P49116	1 Reference(s)
T85U8U	Caspase-3	CASP3	P42574	8 Reference(s)
T23P74	Caspase-9	CASP9	P55211	5 Reference(s)
T88TDZ	RAC-alpha serine/threonine-protein kinase	AKT1	P31749	2 Reference(s)
T71BDH	Mitogen-activated protein kinase 14	MAPK14	Q16539	1 Reference(s)
T67JR8	Heat shock factor protein 1	HSF1	Q00613	2 Reference(s)
T18CWB	Transcriptional activator Myb	MYB	P10242	3 Reference(s)
T79WXA	Mitogen-activated protein kinase 1	MAPK1	P28482	1 Reference(s)
T50SJ8	5'-AMP-activated protein kinase catalytic subunit alpha-2	PRKAA2	P54646	1 Reference(s)
T97FEF	Broad substrate specificity ATP-binding cassette transporter ABCG2	ABCG2	Q9UNQ0	1 Reference(s)
T57L0X	Oxysterols receptor LXR-alpha	NR1H3	Q13133	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	1 Reference(s)
T25Y64	Cholinesterase	BCHE	P06276	1 Reference(s)
T45G32	Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	2 Reference(s)
T27IAF	Lactoylglutathione lyase	GLO1	Q04760	1 Reference(s)
T95A04	Solute carrier organic anion transporter family member 2B1	SLCO2B1	O94956	1 Reference(s)
T98RXH	Focal adhesion kinase 1	PTK2	Q05397	1 Reference(s)
T31YO2	Solute carrier organic anion transporter family member 1A2	SLCO1A2	P46721	1 Reference(s)
T92UWJ	Beta-2 adrenergic receptor	ADRB2	P07550	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	1 Reference(s)
T04H8Y	Beta-secretase 1	BACE1	P56817	2 Reference(s)
T43ZNV	Proteasome subunit beta type-1	PSMB1	P20618	1 Reference(s)
T71K92	Apoptosis regulator Bcl-2	BCL2	P10415	4 Reference(s)
T80TUC	Apoptosis regulator BAX	BAX	Q07812	3 Reference(s)
T20JZ2	Androgen receptor	AR	P10275	2 Reference(s)
T42EAZ	Vascular endothelial growth factor A	VEGFA	P15692	1 Reference(s)
T94DIJ	Protein CIP2A	CIP2A	Q8TCG1	2 Reference(s)
T54OSZ	Pleckstrin	PLEK	P08567	1 Reference(s)
T63FNY	NSFL1 cofactor p47	NSFL1C	Q9UNZ2	1 Reference(s)
T25C2G	Nuclear receptor subfamily 4 group A member 1	NR4A1	P22736	1 Reference(s)
T38T1U	Caspase-8	CASP8	Q14790	1 Reference(s)
T53AOE	Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide	TGFB1	P01137	2 Reference(s)
T31SX8	Bone morphogenetic protein 2	BMP2	P12643	1 Reference(s)
T04MBA	Vascular endothelial growth factor receptor 2	KDR	P35968	1 Reference(s)
T84WE9	Vascular endothelial growth factor receptor 1	FLT1	P17948	1 Reference(s)
T26EZU	Myc proto-oncogene protein	MYC	P01106	1 Reference(s)
T01S8U	Metalloproteinase inhibitor 2	TIMP2	P16035	1 Reference(s)
T04WT7	Fibronectin	FN1	P02751	2 Reference(s)
T15TWZ	Collagen alpha-4(IV) chain	COL4A4	P53420	1 Reference(s)
T31P1D	Metalloproteinase inhibitor 1	TIMP1	P01033	1 Reference(s)
T80GUN	72 kDa type IV collagenase	MMP2	P08253	1 Reference(s)
T80OJF	Interstitial collagenase	MMP1	P03956	1 Reference(s)
T08Q7W	Prostaglandin G/H synthase 2	PTGS2	P35354	1 Reference(s)
T14JSQ	Baculoviral IAP repeat-containing protein 2	BIRC2	Q13490	1 Reference(s)
T36B1Q	Baculoviral IAP repeat-containing protein 5	BIRC5	O15392	1 Reference(s)
T74D4Y	CASP8 and FADD-like apoptosis regulator	CFLAR	O15519	1 Reference(s)
T74I49	Bcl-2-like protein 1	BCL2L1	Q07817	1 Reference(s)
T93WZG	G1/S-specific cyclin-D1	CCND1	P24385	1 Reference(s)
T15JRW	Interferon alpha-inducible protein 27, mitochondrial	IFI27	P40305	2 Reference(s)
T18KNE	NA	MIR146A	NA	2 Reference(s)
T06DT5	Phorbol-12-myristate-13-acetate-induced protein 1	PMAIP1	Q13794	2 Reference(s)
T06ADX	Tyrosine-protein kinase receptor UFO	AXL	P30530	3 Reference(s)
T27I35	NA	MIR223	NA	2 Reference(s)
T77UWH	CCAAT/enhancer-binding protein beta	CEBPB	P17676	1 Reference(s)
T43N2D	Epidermal growth factor receptor	EGFR	P00533	2 Reference(s)
T02GAB	NA	MIR17HG	NA	1 Reference(s)
T14ENF	Microtubule-associated protein 2	MAP2	P11137	1 Reference(s)
T78ZF2	Protein kinase C alpha type	PRKCA	P17252	1 Reference(s)
T93VFT	Endothelin-1	EDN1	P05305	1 Reference(s)
T00OVG	Semaphorin-3A	SEMA3A	Q14563	1 Reference(s)
T67HXL	Glial cell line-derived neurotrophic factor	GDNF	P39905	1 Reference(s)
T09BRP	NA	PKB_RS07820	NA	1 Reference(s)
T50DXZ	NA	MIR126	NA	1 Reference(s)
T53KY7	Cystic fibrosis transmembrane conductance regulator	CFTR	P13569	1 Reference(s)
T28RI5	Zinc finger E-box-binding homeobox 1	ZEB1	P37275	1 Reference(s)
T75NEV	Aquaporin-1	AQP1	P29972	1 Reference(s)
T30AEN	Aquaporin-5	AQP5	P55064	1 Reference(s)
T63GUB	Proto-oncogene c-Fos	FOS	P01100	1 Reference(s)
T16UHV	Nuclear factor of activated T-cells, cytoplasmic 1	NFATC1	O95644	1 Reference(s)
T33OSQ	Sterol regulatory element-binding protein 1	SREBF1	P36956	1 Reference(s)

Herb ID: H0130	Chinese Character: 雷公藤
English Name: Common threewingnut	Latin Name: Tripterygium wilfordii
Chinese Pin Yin : Lei Gong Teng	TCM-ID: TCMH1255
Therapeutic Function in Chinese : 祛风湿	Therapeutic Function in English: For dispelling wind-dampness
Herb Function: Expel wind-dampness, relieve swelling, alleviate pain and dredge the meridian passage

Herb Description

Related Targets (Total: 79)

Related Compounds (Total: 5)