Target Description

Type Detail
Target ID T18CWB
Protein Name Transcriptional activator Myb
Uniprot ID P10242
Protein Name Alias Proto-oncogene c-Myb
Gene ID 4602
Gene Symbol MYB
Gene Alias NA
TTD T99740: Clinical Trial target
Pfam PF07988 ; PF00249 ; PF09316
GO
0006355:regulation of transcription, DNA-templated

0060252:positive regulation of glial cell proliferation

0071300:cellular response to retinoic acid

0051571:positive regulation of histone H3-K4 methylation

0070301:cellular response to hydrogen peroxide

0001666:response to hypoxia

0005829:cytosol

1904899:positive regulation of hepatic stellate cell proliferation

0001228:DNA-binding transcription activator activity, RNA polymerase II-specific

2000845:positive regulation of testosterone secretion

0005654:nucleoplasm

0000278:mitotic cell cycle

1901533:negative regulation of hematopoietic progenitor cell differentiation

0048661:positive regulation of smooth muscle cell proliferation

0045893:positive regulation of transcription, DNA-templated

0043525:positive regulation of neuron apoptotic process

0006338:chromatin remodeling

1902036:regulation of hematopoietic stem cell differentiation

0045944:positive regulation of transcription by RNA polymerase II

0016363:nuclear matrix

0005634:nucleus

0051574:positive regulation of histone H3-K9 methylation

0032967:positive regulation of collagen biosynthetic process

0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding

0045892:negative regulation of transcription, DNA-templated

0000122:negative regulation of transcription by RNA polymerase II

2000491:positive regulation of hepatic stellate cell activation

0000981:DNA-binding transcription factor activity, RNA polymerase II-specific

0071636:positive regulation of transforming growth factor beta production

0045624:positive regulation of T-helper cell differentiation

PDB NA
Drugbank NA
KEGG hsa:4602

Related Compounds  (Total: 4)

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C0792
Name: Celastrol
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C1197
Name: Brucine
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C1221
Name: Catechol
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C1222
Name: Celastrol


Related Herbs  (Total: 38)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0530 Tao Ren Shuang桃仁霜 Peach kernelPrunus persica
H0016 Ji Xue Cao积雪草 Asiatic pennywortCentella asiatica
H0269 Mu Gua木瓜 Chinese floweringquinceChaenomeles sinensis
H0421 Shan Zha Qing Gao山楂清膏 Chinese hawthornCrataegus pinnatifida
H0663 Xiao Ji小蓟 Setose thistleCirsium setosum
H0420 Shan Zha Chou Gao山楂稠膏 Chinese hawthornCrataegus pinnatifida
H0226 Man Yue Mei蔓越莓 CranberryVaccinium oxycoccos
H0158 Liu Ling Ju六棱菊 NALaggera alata
H0941 Da Zao大枣 Chinese dateZiziphus jujuba
H0626 Xi Nan Huang Qin西南黄芩 Yunnan skullcapScutellaria amoena
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0529 Tao Ren桃仁 Peach kernelPrunus persica
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0314 Pu Gong Ying蒲公英 Mongolian dandelionTaraxacum mongolicum
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H1229 Bai Mu Xiang白木香 Chinese eaglewoodAquilaria sinensis
H0772 Yue Ji Hua月季花 Chinese roseRosa chinensis
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0531 Tao Zhi桃枝 Peach juvenile branchPrunus persica
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0284 Nan She Teng南蛇藤 Oriental bittersweetCelastrus orbiculatus
H0130 Lei Gong Teng雷公藤 Common threewingnutTripterygium wilfordii
H0617 Qian Cao Teng茜草藤 NARubia cordifolia
H0315 Pu Gong Ying Jin Gao蒲公英浸膏 Mongolian dandelionTaraxacum mongolicum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0419 Shan Zha山楂 Chinese hawthornCrataegus pinnatifida
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H0527 Tao PeachPrunus persica
H0733 Ye Shan Zha野山楂 nippon bawthornCrataegus pinnatifida
H1244 Huang Miao黄苗 NATaraxacum mongolicum
H0353 Que Mei Teng Gen雀梅藤根 Hedge sageretiaSageretia thea
H0695 Ya Dan Zi鸦胆子 Java bruceaBrucea javanica
H0422 Shan Zha Tan山楂炭 Chinese hawthornCrataegus pinnatifida
H1127 Guang Shan Zha广山楂 Chinese hawthornCrataegus pinnatifida