HIT-result

Type	Detail
Target ID	T36B1Q
Protein Name	Baculoviral IAP repeat-containing protein 5
Uniprot ID	O15392
Protein Name Alias	Apoptosis inhibitor 4; Apoptosis inhibitor survivin
Gene ID	332
Gene Symbol	BIRC5
Gene Alias	API4; IAP4
TTD	T02677: Clinical Trial target
Pfam	PF00653
GO	0005634:nucleus 0050897:cobalt ion binding 0046872:metal ion binding 0019221:cytokine-mediated signaling pathway 0007094:mitotic spindle assembly checkpoint 0005829:cytosol 0000086:G2/M transition of mitotic cell cycle 0007605:sensory perception of sound 0051303:establishment of chromosome localization 0051087:chaperone binding 0032991:protein-containing complex 0008017:microtubule binding 0008270:zinc ion binding 0045892:negative regulation of transcription, DNA-templated 0000777:condensed chromosome kinetochore 0042803:protein homodimerization activity 0043066:negative regulation of apoptotic process 0046982:protein heterodimerization activity 0042802:identical protein binding 0005654:nucleoplasm 0031503:protein-containing complex localization 0019899:enzyme binding 0000281:mitotic cytokinesis 0006468:protein phosphorylation 0007052:mitotic spindle organization 0005876:spindle microtubule 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0015631:tubulin binding 0000278:mitotic cell cycle 0032133:chromosome passenger complex 0005814:centriole 0051726:regulation of cell cycle 0051301:cell division 0030496:midbody 0000775:chromosome, centromeric region 0031267:small GTPase binding 0031536:positive regulation of exit from mitosis 0007059:chromosome segregation 0000228:nuclear chromosome 0042981:regulation of apoptotic process 0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0008284:positive regulation of cell population proliferation 0045931:positive regulation of mitotic cell cycle 0005737:cytoplasm 0005881:cytoplasmic microtubule 0031021:interphase microtubule organizing center
PDB	6YIH ; 4A0I ; 1E31 ; 1XOX ; 3UIJ ; 6SHO ; 3UEE ; 1F3H ; 3UIK ; 4A0N ; 4A0J ; 2RAW ; 3UEF ; 3UII ; 2QFA ; 6YIF ; 2RAX ; 3UEH ; 3UEC ; 3UIH ; 3UIG ; 3UEI ; 3UED ; 6YIE ; 3UEG
Drugbank	DB00206 ; DB05141 ; DB04115
KEGG	hsa:332

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0617	Qian Cao Teng	茜草藤	NA	Rubia cordifolia
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu
H0926	Da Huang	大黄	Medicinal rhubarb	Rheum officinale
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0932	Ba Qia	菝葜	Chinaroot greenbrier	Smilax china
H0315	Pu Gong Ying Jin Gao	蒲公英浸膏	Mongolian dandelion	Taraxacum mongolicum
H0432	She Gan	射干	Blackberrylily	Belamcanda chinensis
H1176	Hei Hu Jiao	黑胡椒	Black pepper	Piper nigrum
H1077	Bai Hu Jiao	白胡椒	white pepper	Piper nigrum
H0269	Mu Gua	木瓜	Chinese floweringquince	Chaenomeles sinensis
H0960	Dang Shen Qing Gao	党参清膏	Root of hairy asiabell	Codonopsis pilosula
H0570	Tu Fu Ling	土茯苓	Glabrous greenbrier	Smilax glabra
H0270	Mu Hu Die	木蝴蝶	Indian trumpetflower	Oroxylum indicum
H0693	Xue Xie	血蝎	Dragon's blood	Daemonorops draco
H1244	Huang Miao	黄苗	NA	Taraxacum mongolicum
H0275	Mu Zei	木贼	Common scouring rush	Equisetum hiemale
H1213	Hu Zhang	虎杖	Japanese fleeceflower	Polygonum cuspidatum
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0226	Man Yue Mei	蔓越莓	Cranberry	Vaccinium oxycoccos
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1166	He Shou Wu	何首乌	Tuber fleeceflower	Polygonum multiflorum
H0130	Lei Gong Teng	雷公藤	Common threewingnut	Tripterygium wilfordii
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0472	Shu Da Huang	熟大黄	NA	Rheum palmatum
H1204	Hu Jiao	胡椒	Black pepper	Piper nigrum
H0314	Pu Gong Ying	蒲公英	Mongolian dandelion	Taraxacum mongolicum
H0626	Xi Nan Huang Qin	西南黄芩	Yunnan skullcap	Scutellaria amoena
H0434	She Pu Tao	蛇葡萄	Ampelopsis	Ampelopsis brevipedunculata
H0284	Nan She Teng	南蛇藤	Oriental bittersweet	Celastrus orbiculatus
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0927	Da Huang Jin Gao	大黄浸膏	Medicinal rhubarb	Rheum officinale
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0765	Chi Dou	赤豆	Assuki bean	Vigna angularis
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H0416	Shan Shen	山参	NA	Panax ginseng
H0353	Que Mei Teng Gen	雀梅藤根	Hedge sageretia	Sageretia thea
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0928	Da Huang Liu Jin Gao	大黄流浸膏	Medicinal rhubarb	Rheum officinale
H0258	Mo Han Lian	墨旱莲	Yerbadetajo	Eclipta prostrata
H0958	Dang Shen	党参	Pilose asiabell	Codonopsis pilosula
H1117	Guan Zhong	贯众	Male fern rhizome	Dryopteris crassirhizoma
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H0295	Bi Ba	荜茇	Long pepper	Piper longum
H0883	Chuan She Gan	川射干	Blackberrylily	Belamcanda chinensis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description

Related Compounds (Total: 12)

Related Herbs (Total: 45)