HIT-result

ID: C0039	Common name: Ellagic Acid
IUPAC: NA	CAS: CAS:476-66-4
Chembl ID: CHEMBL6246	Pubchem ID: CID:5281855
Formula: C14H6O8	TCM-ID: TCMC1102
Smiles: C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O
Alias: 2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione; 2,3,7,8-Tetrahydroxy-chromeno[5,4,3-cde]chromene-5,10-dione; Alizarin yellow; Alizarine Yellow; Benzoaric acid; C.I. 55005; C.I. 75270; Elagostasine; Eleagic acid; Ellagic acid; Ellagic acid LT; G 91006; Gallogen; Gallogen (astringent); LDN 0097519; Lagistase; [1,1'-Biphenyl]-2,2'-dicarboxylic acid, 4,4',5,5',6,6'-hexahydroxy-, di-δ-lactone	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T95Y0K	Sphingosine kinase 1	SPHK1	Q9NYA1	A	1 Reference(s)
T20JZ2	Androgen receptor	AR	P10275	A	1 Reference(s)
T06Q1R	Amine oxidase [flavin-containing] B	MAOB	P27338	A	1 Reference(s)
T21K0F	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	ATP2A3	Q93084	A	1 Reference(s)
T92X7D	Nucleoside diphosphate kinase A	NME1	P15531	A	1 Reference(s)
T14AON	Nucleoside diphosphate kinase, mitochondrial	NME4	O00746	A	1 Reference(s)
T13KGH	Tyrosinase	TYR	P14679	A	1 Reference(s)
T01QLH	Estrogen receptor	ESR1	P03372	A	1 Reference(s)
T76EHP	Glutathione S-transferase A1	GSTA1	P08263	B	1 Reference(s)
T48XM4	Glutathione S-transferase Mu 2	GSTM2	P28161	B	1 Reference(s)
T25H22	Protein kinase C beta type	PRKCB	P05771	B	1 Reference(s)
T87WYU	Glutathione S-transferase Mu 1	GSTM1	P09488	B	1 Reference(s)
T24CYX	Chitin synthase 2	CHS2	P14180	B	1 Reference(s)
T46AQJ	Glutathione S-transferase P	GSTP1	P09211	B	1 Reference(s)
T62F1Y	Glutathione S-transferase A2	GSTA2	P09210	B	1 Reference(s)
T79KQO	NF-kappa-B inhibitor alpha	NFKBIA	P25963	B	1 Reference(s)
T10KMJ	Insulin-like growth factor II	IGF2	P01344	B	1 Reference(s)
T54CIF	Interleukin-8	CXCL8	P10145	C	1 Reference(s)
T50WOV	ATP-dependent translocase ABCB1	ABCB1	P08183	C	1 Reference(s)
T29MD1	Mitogen-activated protein kinase 8	MAPK8	P45983	C	1 Reference(s)
T42FMQ	Mitogen-activated protein kinase kinase kinase 1	MAP3K1	Q13233	C	1 Reference(s)
T12T4H	Brain-derived neurotrophic factor	BDNF	P23560	C	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0104	Bai Zhu	白术	Largehead atractylodes	Atractylodes macrocephala
H0256	Ming Dang Shen	明党参	Medicinal changium	Changium smyrnioides
H0219	Man Shan Hong	满山红	Dahurian rhododendron	Rhododendron dauricum
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0868	Chuan Du Huo	川独活	Doubleteeth pubescent angelica	Angelica pubescens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1170	He Zi	诃子	Medicine terminalia	Terminalia chebula
H0342	Qing Hao	青蒿	sweet wormwood	Artemisia carvifolia
H0656	Xiao Bo Gen	小檗根	Barberry root	Berberis julianae
H0344	Qing Guo	青果	Olive	Canarium album
H0772	Yue Ji Hua	月季花	Chinese rose	Rosa chinensis
H0237	Mei Gui Hua	玫瑰花	Rugose rose flower	Rosa rugosa
H0974	Di Jin Cao	地锦草	Humifuse euphorbia	Euphorbia humifusa
H0068	Jin Ying Zi Rou	金樱子肉	Cherokee rose seed	Rosa laevigata
H0069	Jin Ying Zi Ti Qu Ye	金樱子提取液	Cherokee rose seed	Rosa laevigata
H0163	Long Dan Jin Gao	龙胆浸膏	Rough gentian	Gentiana scabra
H1025	Fan Bai Cao	翻白草	Discolor cinquefoil	Potentilla discolor
H1137	Gui Yuan	桂圆	NA	Dimocarpus longan
H0195	Ma Chi Xian	马齿苋	Purslane	Portulaca oleracea
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H1091	Gao Li Shen	高丽参	Korea ginseng	Radix ginseng korea
H1097	Gong Ding Xiang	公丁香	NA	Syzygium aromaticum
H0975	Di Mian Cao	地绵草	NA	Euphorbia humifusa
H0343	Qing Hao Zi	青蒿子	sweet wormwood	Artemisia carvifolia
H0464	Shi Liu Zi	石榴子	NA	Punica granatum
H0941	Da Zao	大枣	Chinese date	Ziziphus jujuba
H0759	Yu Gan Zi	余甘子	Emblic leafflower fruit	Fructus phyllanthi
H0345	Qing Guo Tan	青果炭	white olive	Canarium album
H0959	Dang Shen Lu Tou	党参芦头	Rhizome of pilose asiabell	Rhizoma codonopsis pilosulae
H0267	Mu Ding Xiang	母丁香	Clove fruit	Fructus caryophylli
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H1035	Bai Fu Ling	白茯苓	white indian bread	Wolfiporia cocos
H0060	Jin Si Ku Lian	金丝苦楝	NA	Cardiospermum halicacabum
H0066	Jin Ying Gen	金樱根	root of cherokee rose	Radix rosae laevigatae
H0461	Shi Jun Zi Ren	使君子仁	NA	Combretum indicum
H0070	Jing Da Ji	京大戟	Peking euphorbia root	Radix euphorbiae pekinensis
H0967	Di Er Cao	地耳草	Japanese stJohn’swort	Hypericum japonicum
H0227	Mang Guo Ye	芒果叶	Mango leaf	Mangifera indica
H0288	Niu Bang Cao	牛蒡草	greater burdock	Arctium lappa
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0463	Shi Liu Pi	石榴皮	Pomegranate peel	Punica granatum
H0934	Da Ji	大戟	Peking spurge root	Radix euphorbiae pekinensis
H0784	Chi Shao	赤芍	Red peony root	Paeonia obovata
H0990	Ding Xiang	丁香	Clove tree	Syzygium aromaticum
H1221	Hua Xiang Shu Guo Xu	化香树果序	NA	Platycarya strobilacea
H0162	Long Dan	龙胆	Rough gentian	Gentiana scabra
H1056	Fu Pen Zi	覆盆子	Red-and-Yellow garden raspberry	Rubus idaeus
H1082	Gan Lan	橄榄	Cabbage	Canarium album
H0515	Suan Shi Liu	酸石榴	Pomegranate	Punica granatum
H0462	Shi Liu	石榴	Pomegranate fruit	Punica granatum
H0634	Xian He Cao	仙鹤草	Japanese argimonia	Agrimonia pilosa var. japonica
H0252	Mian Da Ji	绵大戟	NA	Euphorbia pekinensis
H1171	He Zi Rou	诃子肉	Medicine terminalia	Terminalia chebula
H0128	Lao Guan Cao	老鹳草	Wilford cranesbill	Geranium wilfordii
H1220	Hua Xiang Shu Guo	化香树果	NA	Platycarya strobilacea
H1034	Fei Yang Cao	飞杨草	NA	Euphorbia hirta
H0429	Shao Yao	芍药	Red peony root	Paeonia obovata
H0635	Xian He Cao Jin Gao Fen	仙鹤草浸膏粉	Japanese argimonia	Agrimonia pilosa var. japonica
H0547	Cang Qing Guo	藏青果	Myrobalan	Terminalia chebula
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0067	Jin Ying Zi	金樱子	Cherokee rose seed	Rosa laevigata
H1009	Du Huo	独活	Doubleteeth pubescent angelica	Angelica pubescens
H1130	Guang Zao	广枣	fruit of axillary choerospondias	Fructus choerospondiatis

Compound Description

Related Targets (Total: 22)

Related Herbs (Total: 64)