Target Description
| Type | Detail |
|---|---|
| Target ID | T36HAE |
| Protein Name | D-amino-acid oxidase |
| Uniprot ID |
P14920 |
| Protein Name Alias | DAAO; DAMOX; DAO; EC 1.4.3.3 |
| Gene ID |
1610 |
| Gene Symbol | DAO |
| Gene Alias | DAMOX |
| TTD | T33124: Clinical Trial target |
| Pfam | PF01266 |
| GO |
0042802:identical protein binding
0005737:cytoplasm 0008104:protein localization 0019478:D-amino acid catabolic process 0042416:dopamine biosynthetic process 0005777:peroxisome 0055130:D-alanine catabolic process 0019752:carboxylic acid metabolic process 0006562:proline catabolic process 0005829:cytosol 0003884:D-amino-acid oxidase activity 0005782:peroxisomal matrix 0070178:D-serine metabolic process 0005778:peroxisomal membrane 0036088:D-serine catabolic process 0071949:FAD binding |
| PDB | 3W4I ; 2E82 ; 2E49 ; 3ZNQ ; 3ZNN ; 2GNZ ; 2DU8 ; 3CUK ; 2E4A ; 3W4J ; 4QFC ; 3ZNO ; 3W4K ; 4QFD ; 3ZNP ; 3G3E ; 5ZJ9 ; 5ZJA ; 6KBP ; 2E48 |
| Drugbank | DB02988 ; DB03531 ; DB03225 ; DB02838 ; DB07979 ; DB04166 ; DB03793 ; DB03147 |
| KEGG | hsa:1610 |
Related Herbs (Total: 67)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0747 | An Xi Xiang | 安息香 | Sumatra snowbel | Styrax benzoin |
| H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
| H0693 | Xue Xie | 血蝎 | Dragon's blood | Daemonorops draco |
| H0139 | Lian Qiao | 连翘 | Weeping forsythia | Forsythia suspensa |
| H0688 | Xuan Shen | 玄参 | Ningpo figwort | Scrophularia ningpoensis |
| H0500 | Can Yong | 蚕蛹 | Silkworm chrysalis | Bombyx mori |
| H1134 | Bai Jiang Can | 白僵蚕 | Silkworm larva | Bombyx mori |
| H0022 | Jia Ju | 假蒟 | Sarmentose pepper | Piper sarmentosum |
| H0461 | Shi Jun Zi Ren | 使君子仁 | NA | Combretum indicum |
| H0053 | Jin Lian Hua | 金莲花 | Chinese globeflower | Trollius chinensis |
| H0937 | Da Qing Ye | 大青叶 | Indigo-coloured woad leaf | Isatis indigotica |
| H0607 | Wu Wei Zi Jin Chu Wu | 五味子浸出物 | Five-flavor berry | Schisandra chinensis |
| H0853 | Zi Wan | 紫菀 | Tatarion aster | Aster tataricus |
| H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0137 | Ban Lan Gen | 板蓝根 | Indigowoad root | Isatis indigotica |
| H0490 | Can Jian | 蚕茧 | Silk cocoon | Bombyx mori |
| H1162 | Hang Shao | 杭芍 | White peony root | Paeonia albiflora |
| H0605 | Wu Wei Zi | 五味子 | Chinese magnoliavine | Schisandra chinensis |
| H0076 | Jing Tian San Qi | 景天三七 | Chrusanthemum-like groundsel | Gynura segetum |
| H0154 | Ai Ye You | 艾叶油 | Argy wormwood leaf | Artemisia argyi |
| H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
| H0609 | Wu Wei Zi Liu Jin Gao | 五味子流浸膏 | Five-flavor berry | Schisandra chinensis |
| H0265 | Mu Da Qing Ye | 木大青叶 | Indigo-coloured woad leaf equivalent | Isatis indigotica |
| H0495 | Can Sha | 蚕砂 | Silkworm excrement | Bombyx mori |
| H0973 | Di Huang Tan | 地黄炭 | Rehmanniae | Rehmannia glutinosa |
| H0429 | Shao Yao | 芍药 | Red peony root | Paeonia obovata |
| H1156 | Ai Di Huang | 矮地黄 | Rehmanniae | Rehmannia glutinosa |
| H0784 | Chi Shao | 赤芍 | Red peony root | Paeonia obovata |
| H1133 | Gui Jian Yu | 鬼箭羽 | Winged euonymus | Euonymus alatus |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0768 | Yuan Shen | 元参 | Figwort root | Scrophularia ningpoensis |
| H1223 | Huai Hun Cao | 还魂草 | NA | Aster tataricus |
| H0023 | Bai Shao Gan Jin Gao | 白芍干浸膏 | Common peony | Paeonia lactiflora |
| H0131 | Ban Lan | 板蓝 | Indigowoad root | Isatis indigotica |
| H0498 | Si Ji Cai | 四季菜 | Ghostplant wormwood | Artemisia lactiflora |
| H0103 | Ai Ye | 艾叶 | Argy wormwood leaf | Artemisia argyi |
| H0711 | Yuan Hua Zhi Tiao | 芫花枝条 | stem of lilac daphne | Daphne genkwa |
| H0263 | Mu Ban Lan Gen | 木板蓝根 | Indigowoad root | Isatis indigotica |
| H1036 | Fen Dan Pi | 粉丹皮 | Tree peony bark | Paeonia suffruticosa |
| H0021 | Bai Shao | 白芍 | Common peony | Paeonia lactiflora |
| H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
| H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
| H0606 | Wu Wei Zi Chun Jin Gao | 五味子醇浸膏 | Five-flavor berry | Schisandra chinensis |
| H0918 | Cu Yuan Hua | 醋芫花 | Lilac daphne | Daphne genkwa |
| H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
| H0972 | Di Huang | 地黄 | Rehmanniae | Rehmannia glutinosa |
| H1079 | Gan Di Huang | 干地黄 | Adhesive rehmannia dried root | Rehmannia glutinosa |
| H0708 | Yuan Hua Gen | 芫花根 | Lilac daphne root | Daphne genkwa |
| H0710 | Yuan Hua Tiao | 芫花条 | stem of lilac daphne | Daphne genkwa |
| H0578 | Tu San Qi | 土三七 | Chrusanthemum-like groundsel | Gynura segetum |
| H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
| H0476 | Can E | 蚕蛾 | Silkworm | Bombyx mori |
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0565 | Tu Bie Chong | 土鳖虫 | Cockroach | Eupolyphaga sinensis |
| H0250 | Mi Zi Wan | 蜜紫菀 | Tatarian aster | Aster tataricus |
| H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
| H0608 | Wu Wei Zi Jin Gao | 五味子浸膏 | Five-flavor berry | Schisandra chinensis |
| H0707 | Yuan Hua | 芫花 | Lilac daphne | Daphne genkwa |
| H0679 | Xing Ren | 杏仁 | Apricot seed | Prunus armeniaca |
| H0024 | Jia 蒟ye | 假蒟叶 | Sarmentose pepper | Piper sarmentosum |
| H0473 | Shu Di Huang | 熟地黄 | Adhesive rehmannia cocked root | Rehmannia glutinosa |
| H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
| H0696 | Ya Jiao Ai | 鸭脚艾 | Ghostplant wormwood | Artemisia lactiflora |
| H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
| H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
| H1026 | Fan Hun Cao | 返魂草 | Tatarian aster | Aster tataricus |