Compound Description

ID:   C0399 Common name:   Sesamin
IUPAC:  5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole CAS:  CAS:607-80-7
Chembl ID:   CHEMBL252915 Pubchem ID:   CID:72307
Formula:  C20H18O6 TCM-ID:  TCMC2066
Smiles:  C1C2C(COC2C3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6
Alias:

1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, [1S-(1α,3aα,4α,6aα)]-;

1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-, (1S,3aR,4S,6aR)-;

(1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis[1,3-benzodioxole];

1H,3H-Furo[3,4-c]furan, 1,3-benzodioxole deriv.;

(+)-Sesamin;

Fagarol;

NSC 36403;

Sesamin;

Sesamin, (+)-;

Sesavita;

Sezamin;

Tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan;

Zengxiaomin;

d-Sesamin;

δ-Sesamin
Structure:

Related Targets  (Total: 24)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T11GYO Peroxisomal acyl-coenzyme A oxidase 1ACOX1 Q15067
A 1 Reference(s)
T08UWG NADPH oxidase 3NOX3 Q9HBY0
A 1 Reference(s)
T87UKX Glucose-6-phosphate 1-dehydrogenaseG6PD P11413
A 1 Reference(s)
T92UBJ Acetyl-CoA carboxylase 1ACACA Q13085
A 1 Reference(s)
T16MRJ Trifunctional enzyme subunit beta, mitochondrialHADHB P55084
B 1 Reference(s)
T20HY9 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrialDECR1 Q16698
B 1 Reference(s)
T43FA8 Medium-chain specific acyl-CoA dehydrogenase, mitochondrialACADM P11310
B 1 Reference(s)
T60LKM Peroxisomal bifunctional enzymeEHHADH Q08426
B 1 Reference(s)
T93WZG G1/S-specific cyclin-D1CCND1 P24385
B 1 Reference(s)
T90ZS8 Endothelin-converting enzyme 1ECE1 P42892
B 1 Reference(s)
T09H2Z Nitric oxide synthase, inducibleNOS2 P35228
B 1 Reference(s)
T74JJN Fatty acid synthaseFASN P49327
B 1 Reference(s)
T14W2H ATP-citrate synthaseACLY P53396
B 1 Reference(s)
T69DAO Enoyl-CoA delta isomerase 1, mitochondrialECI1 P42126
B 1 Reference(s)
T64UH1 Nitric oxide synthase, endothelialNOS3 P29474
C 1 Reference(s)
T44KU9 Cytochrome P450 2B6CYP2B6 P20813
C 1 Reference(s)
T61OY3 UDP-glucuronosyltransferase 1A1UGT1A1 P22309
C 1 Reference(s)
T69NG6 Interleukin-10IL10 P22301
C 1 Reference(s)
T20TB8 NADPH oxidase 1NOX1 Q9Y5S8
C 1 Reference(s)
T33OSQ Sterol regulatory element-binding protein 1SREBF1 P36956
C 1 Reference(s)
T22OPB Nuclear factor erythroid 2-related factor 2NFE2L2 Q16236
C 1 Reference(s)
T93YV8 Tumor necrosis factor receptor superfamily member 11BTNFRSF11B O00300
C 1 Reference(s)
T86ROZ Heme oxygenase 1HMOX1 P09601
C 1 Reference(s)
T03G09 Tumor necrosis factor ligand superfamily member 11TNFSF11 O14788
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 31)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H1055 Bai Guo Ren白果仁 ginkgoGinkgo biloba
H1207 Hu Ma胡麻 white seed of oriental sesameSesamum indicum
H1208 Hu Ma Ren胡麻仁 white seed of oriental sesameSesamum indicum
H0096 Ju San Qi菊三七 NAGynura japonica
H0788 Zhang Nao Zi樟脑子 CamphorarCinnamomum camphora
H0295 Bi Ba荜茇 Long pepperPiper longum
H0918 Cu Yuan Hua醋芫花 Lilac daphneDaphne genkwa
H0158 Liu Ling Ju六棱菊 NALaggera alata
H1051 Bai Guo白果 Ginkgo nutGinkgo biloba
H0583 Tu Si Zi Teng菟丝子藤 Dodder seedCuscuta australis
H0790 Zhang Shu Zi樟树子 Camphor treeCinnamomum camphora
H0629 Xi Xin细辛 Siebold wildgingerAsarum sieboldii
H0789 Zhang Shu Gen樟树根 Camphor treeCinnamomum camphora
H0848 Zi Jin Niu紫金牛 Japanese ardisiaArdisia japonica
H0967 Di Er Cao地耳草 Japanese stJohn’swortHypericum japonicum
H0581 Tu Si Zi菟丝子 Dodder seedCuscuta australis
H0693 Xue Xie血蝎 Dragon's bloodDaemonorops draco
H0707 Yuan Hua芫花 Lilac daphneDaphne genkwa
H0710 Yuan Hua Tiao芫花条 stem of lilac daphneDaphne genkwa
H0787 Zhang Nao樟脑 CamphorarCinnamomum camphora
H0750 Yin Xing Ye银杏叶 Folium ginkgoGinkgo biloba
H1181 Hei Zhi Ma黑芝麻 Oriental sesameSesamum indicum
H1086 Bai Hua Cai Zi白花菜子 Common spiderflower seedCleome gynandra
H0580 Tu Si Rou菟丝肉 Dodder seedCuscuta australis
H0098 Ju Ye San Qi菊叶三七 NAGynura japonica
H0708 Yuan Hua Gen芫花根 Lilac daphne rootDaphne genkwa
H0022 Jia Ju假蒟 Sarmentose pepperPiper sarmentosum
H0024 Jia 蒟ye假蒟叶 Sarmentose pepperPiper sarmentosum
H0786 Zhang Mu樟木 Ligum cinmamomi camphoraeCinnamomum camphora
H0233 Mao Liang Mian Zhen毛两面针 NAZanthoxylum nitidum
H0711 Yuan Hua Zhi Tiao芫花枝条 stem of lilac daphneDaphne genkwa