HIT-result

Type	Detail
Target ID	T46HRF
Protein Name	Growth hormone receptor
Uniprot ID	P10912
Protein Name Alias	GH receptor; Somatotropin receptor
Gene ID	2690
Gene Symbol	GHR
Gene Alias	NA
TTD	T02333: Successful target
Pfam	PF12772 ; PF00041 ; PF09067
GO	0046898:response to cycloheximide 0040014:regulation of multicellular organism growth 0019838:growth factor binding 0070195:growth hormone receptor complex 0019221:cytokine-mediated signaling pathway 0005829:cytosol 0009986:cell surface 0000187:activation of MAPK activity 0046427:positive regulation of receptor signaling pathway via JAK-STAT 0009897:external side of plasma membrane 0050731:positive regulation of peptidyl-tyrosine phosphorylation 0042803:protein homodimerization activity 0042802:identical protein binding 0005615:extracellular space 0032870:cellular response to hormone stimulus 0060396:growth hormone receptor signaling pathway 0031623:receptor internalization 0042445:hormone metabolic process 0016021:integral component of membrane 0036464:cytoplasmic ribonucleoprotein granule 0007259:receptor signaling pathway via JAK-STAT 0005576:extracellular region 0043235:receptor complex 0040018:positive regulation of multicellular organism growth 0060397:growth hormone receptor signaling pathway via JAK-STAT 0019530:taurine metabolic process 0004896:cytokine receptor activity 0004903:growth hormone receptor activity 0005886:plasma membrane 0042976:activation of Janus kinase activity 0070064:proline-rich region binding 0005887:integral component of plasma membrane 0019901:protein kinase binding 0042531:positive regulation of tyrosine phosphorylation of STAT protein 0017046:peptide hormone binding 0006897:endocytosis 0032355:response to estradiol 0019955:cytokine binding 0048009:insulin-like growth factor receptor signaling pathway
PDB	1KF9 ; 3HHR ; 5OHD ; 1AXI ; 1HWG ; 5OEK ; 1A22 ; 2AEW ; 1HWH
Drugbank	DB00082 ; DB00052 ; DB15093 ; DB09098
KEGG	hsa:2690

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0277	Nan Ban Lan Gen	南板蓝根	Indigowoad root	Baphicacanthus cusia
H0952	Dan Xiang Chi	淡香豉	NA	Glycine max
H1096	Ge Hua	葛花	flower bud of lobed kudzuvine	Pueraria lobata
H0405	Shan Dou Gen	山豆根	Tonkin sophora root	Sophora subprostrata
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1066	Gan Cao	甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1021	E Da Xia	莪大夏	NA	Oxytropis falcata
H1152	Bai Jie Zi	白芥子	White mustard seed	Sinapis alba
H0017	Ji Xue Teng	鸡血藤	Suberect spatholobus stem	Spatholobus suberectus
H1070	Gan Cao Gan Gao Fen	甘草干膏粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1247	Huang Qi	黄芪	Membranous milkvetch	Astragalus membranaceus
H1248	Huang Qi Gan Jin Gao	黄芪干浸膏	Membranous milkvetch	Astragalus membranaceus
H0981	Dian Ji Xue Teng Gao Fen	滇鸡血藤膏粉	Suberect spatholobus stem	Spatholobus suberectus
H1007	Dou You	豆油	Soybean oil	Glycine max
H0109	Ku Lian Zi	苦楝子	NA	Melia azedarach
H0027	Jiang Gao	姜膏	Soybean paste	Glycine max
H0019	Ji Xue Teng Gao	鸡血藤膏	Suberect spatholobus stem	Spatholobus suberectus
H1072	Gan Cao Gao	甘草膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1074	Gan Cao Jin Gao	甘草浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0705	Yan Hu Lu Ba	盐胡芦巴	Fenugreek	Trigonella foenum-graecum
H1250	Huang Qi Ti Qu Ye	黄芪提取液	Membranous milkvetch	Astragalus membranaceus
H1069	Gan Cao Gan Gao	甘草干膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0995	Dong Chong Xia Cao	冬虫夏草	Aweto	Cordyceps sinensis
H0018	Ji Xue Teng Gan Gao	鸡血藤干膏	Suberect spatholobus stem	Spatholobus suberectus
H0108	Ku Lian Pi	苦楝皮	Chinaberry-tree bark	Melia azedarach
H0444	Sheng Gan Cao	生甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0026	Jiang	姜	Soybean paste	Glycine max
H1075	Gan Cao Liu Jin Gao	甘草流浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1094	Ge Gen	葛根	Lobed kudzuvine root	Pueraria lobata
H1249	Huang Qi Jin Gao	黄芪浸膏	Membranous milkvetch	Astragalus membranaceus
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0031	Jiang Tan	姜炭	Soybean paste	Glycine max
H0897	Chuan Lian	川楝	Chinaberry	Melia azedarach
H1073	Gan Cao Jie	甘草节	Glycyrrhiza uralensis fisch	Glycyrrhiza uralensis
H1095	Ge Gen Gan Jin Gao	葛根干浸膏	Lobed kudzuvine root	Pueraria lobata
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0944	Dan Dou Gu	淡豆鼓	NA	Glycine max
H1067	Gan Cao Fen	甘草粉	Glycyrrhiza inflata	Glycyrrhiza uralensis
H0571	Tu Gan Cao	土甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1080	Gan Ge	干葛	Lobed kudzuvine root	Pueraria lobata
H1071	Gan Cao Gan Jin Gao	甘草干浸膏	Glycyrrhiza inflata	Glycyrrhiza uralensis
H1174	Hei Da Dou	黑大豆	Black soyabean	Glycine max
H0278	Nan Ban Lan Gen Jin Gao Fen	南板蓝根浸膏粉	Indigowoad root	Baphicacanthus cusia
H0240	Mi Gan Cao	蜜甘草	Glycyrrhiza inflata	Glycyrrhiza uralensis

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 44)