Compound Description
| ID: C1208 | Common name: Calycosin |
| IUPAC: 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one | CAS: CAS:20575-57-9 |
| Chembl ID: CHEMBL241608 | Pubchem ID: CID:5280448 |
| Formula: C16H12O5 | TCM-ID: TCMC855 |
| Smiles: COc1ccc(cc1O)c1coc2c(c1=O)ccc(c2)O | |
| Alias:
Isoflavone, 3',7-dihydroxy-4'-methoxy-;
7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3',7-Dihydroxy-4'-methoxyisoflavone; 3'-Hydroxyformononetin; 7,3'-Dihydroxy-4'-methoxyisoflavone; 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)benzopyran-4-one; Calycosin; Cyclosin; Cyclosin (isoflavone) |
Structure:
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Related Targets (Total: 6)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T61J7T | Mothers against decapentaplegic homolog 2 | SMAD2 |
Q15796 |
A | 1 Reference(s) |
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
A | 1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
C | 1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
C | 1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
C | 1 Reference(s) |
| T40G6B | Prostaglandin reductase 1 | PTGR1 |
Q14914 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 41)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0402 | Sha Yuan Zi | 沙苑子 | Flatstem milkvetch seed | Semen astragali complanati |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1250 | Huang Qi Ti Qu Ye | 黄芪提取液 | Membranous milkvetch | Astragalus membranaceus |
| H0111 | Ku Shen | 苦参 | Lightyellow sophora | Sophora flavescens |
| H0277 | Nan Ban Lan Gen | 南板蓝根 | Indigowoad root | Baphicacanthus cusia |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0533 | Teng Ku Shen | 藤苦参 | NA | Sophora flavescens |
| H0401 | Sha Yuan Ji Li | 沙苑蒺藜 | Seed of flaststem milkvetch | Semen astragali complanati |
| H1152 | Bai Jie Zi | 白芥子 | White mustard seed | Sinapis alba |
| H0201 | Ma Huang Jin Gao | 麻黄浸膏 | Chinese ephedra | Ephedra sinica |
| H0200 | Ma Huang Gen | 麻黄根 | Chinese ephedra root | Ephedra sinica |
| H0956 | Dang Gui Gan Jin Gao | 当归干浸膏 | NA | Angelica sinensis |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0561 | Tong Ji Li | 潼蒺藜 | Flatstem milkvetch seed | Semen astragali complanati |
| H0018 | Ji Xue Teng Gan Gao | 鸡血藤干膏 | Suberect spatholobus stem | Spatholobus suberectus |
| H1247 | Huang Qi | 黄芪 | Membranous milkvetch | Astragalus membranaceus |
| H0957 | Dang Gui Teng | 当归藤 | NA | Embelia parviflora |
| H0198 | Ma Huang Gao | 麻黄膏 | Chinese ephedra | Ephedra sinica |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0019 | Ji Xue Teng Gao | 鸡血藤膏 | Suberect spatholobus stem | Spatholobus suberectus |
| H0197 | Ma Huang | 麻黄 | Chinese ephedra | Ephedra sinica |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0826 | Chu Mu Dan | 臭牡丹 | rose glorybower | Clerodendrum bungei |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0278 | Nan Ban Lan Gen Jin Gao Fen | 南板蓝根浸膏粉 | Indigowoad root | Baphicacanthus cusia |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0955 | Dang Gui | 当归 | Chinese angelica | Angelica sinensis |
| H1142 | Guo Jiang Long | 过江龙 | Complanate clubmoss | Millettia dielsiana |
| H0981 | Dian Ji Xue Teng Gao Fen | 滇鸡血藤膏粉 | Suberect spatholobus stem | Spatholobus suberectus |
| H0017 | Ji Xue Teng | 鸡血藤 | Suberect spatholobus stem | Spatholobus suberectus |
| H1021 | E Da Xia | 莪大夏 | NA | Oxytropis falcata |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1249 | Huang Qi Jin Gao | 黄芪浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0246 | Mi Ma Huang | 蜜麻黄 | Ephedra equisetin | Ephedra sinica |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H0705 | Yan Hu Lu Ba | 盐胡芦巴 | Fenugreek | Trigonella foenum-graecum |
| H1248 | Huang Qi Gan Jin Gao | 黄芪干浸膏 | Membranous milkvetch | Astragalus membranaceus |
| H0575 | Tu Ku Shen | 土苦参 | all-grass of hooker winghead | Sophora flavescens |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
Ckey description of the interaction between compound and target